The scientific objective of FLIMagin3D is to synergistically evolve key aspects in FLIM imaging across disciplines by advancing the acquisition of FLIM data and the analysis pipeline, by developing improved platforms that facilitate imaging for a wide range of (bio)medical, chemical and biophysical applications, and by advancing the state-of-the-art in FLIM biosensors. Through real-world biological and biomedical research lines across the partners we can showcase the validity and power of our developments and unify in streamlining FLIM as an accessible and robust tool.
FLIM (Fluorescence Lifetime Imaging Microscopy) is an imaging technique based on the differences in the exponential decay rate of the photon emission of a fluorophore from a sample, extremely useful to map protein-protein interactions and biochemical reactions in living cells. One can gain a wealth of information about dynamic live 3D systems – small organisms and interspecies communities, multicellular aggregates, organoids and assembloids, biofabricated microtissues and indeed live tissues.
This aim will be achieved by the following Research Objectives (RO):
- To create, characterise, standardise and test cost-effective platforms adaptability to all of the various user communities, and to enhance existing imaging capabilities [Doctoral Candidates (DC)2, 6, 9]]
- Optimise the data acquisition and user-data interface whereby large amounts of data are quickly and correctly acquired, processed and interpreted under control of intelligent software [DCs 1, 7, 8, 10]
- Establish a library of tools to act as biosensors, perturbers (‘actuators’) and microenvironments to assess biological activities and processes, and interrogate such activity non-invasively and reproducibly. [DCs 3, 4,5, 10]
These positions have a flexible start from 1st July - 1st September 2023.
Who is eligible
Candidates of any nationality completing the following criteria:
- Candidates must not have resided or carried out their main activity (work, studies, etc.) in the country of the first recruiting organization for more than 12 months in the 3 years immediately prior to their recruitment. The date of recruitment means the first day of the employment of the researcher for the purposes of the action (i.e. the starting date indicated in the employment contract/equivalent direct contract).
- Candidates shall, at the date of recruitment by the host organization, be in the first four years of their research careers and have not been awarded a doctoral degree.
- Candidates must have a master's degree or equivalent diploma in biomedical engineering, computer engineering, biomedical sciences, biochemistry, Materials or related disciplines.
- Candidates may be required to provide documentation proving their eligibility for recruitment, i.e. to provide supporting documentation proving their place(s) of residence or work during the previous 3 years.
- Candidates must have a high level of proficiency in written and spoken English, which will be assessed with the application and the interview, respectively.
- Candidates must submit their applications through the project website: www.flIMAGIN3D.com Each candidate can apply to a maximum of three individual PhD projects.)
Deadline: 15 April 2023
More information: https://flimagin3d.com/