How to become an effective science-policy advisor? The science-policy interactions have a longstanding relationship with complex dynamics. The COVID pandemic was only one of the ‘wicked problem’, where decision-makers called for science-informed advice. This report showcases 16 lessons learnt from the event Good Advice for (Young) Science-Policy Advisors, organised by Science Europe, FORMAS and Marie Curie Alumni Association on 29 April 2022.