The Innovative Training Network (ITN) Training towards Innovative Personalized Antibiotic Therapy (TIPAT) has started March 1, 2020. TIPAToffers a cutting-edge training-by-research program for 15 Early stage researchers (ESRs) / PhD candidates, of which 13 positions are still available. TIPAT is part of the Marie Skłodowska-Curie International Training Network (ITN) of the European Commission. ESRs in TIPAT will be part of an international network of universities, hospitals and companies. The duration of all ESR positions is 36 or 48 months depending on the host institute, and should lead to a PhD degree.
Hosting institutes
ESR positions are available at the following institutes:
Leiden University (The Netherlands): ESR6, ESR7, ESR15
Uppsala University (Sweden): ESR9, ESR10, ESR14
Medical University of Wien (Austria): ESR1, ESR2, ESR8
Paul Ehrlich Institute (Germany): ESR11, ESR12
Jena University Hospital (Germany): ESR5, ESR13
University of Udine (Italy): ESR3, ESR4
Available ESR projects
ESR 1: Host factors predicting target site penetration of antibiotics in difficult to treat patient populations
Host institution: Medical University of Wien (www.meduniwien.ac.at)
Planned start of employment: 01-09-2020
Requested background/experience: medicine, clinical pharmacology
Lead supervisor: Prof. Markus Zeitlinger (markus.zeitlinger@meduniwien.ac.at)
ESR 2: Host factors impacting protein binding of highly protein bound drugs in‐vivo
Host institution: Medical University of Wien (www.meduniwien.ac.at)
Planned start of employment: 01-09-2020
Requested background/experience: medicine, clinical pharmacology
Lead supervisor: Prof. Markus Zeitlinger (markus.zeitlinger@meduniwien.ac.at)
ESR 3: Integrating TDM and PK/PD to predict outcomes in sepsis and HAP/VAP
Host institution: University of Udine (www.uniud.it)
Planned start of employment: 01-09-2020
Requested background/experience: medicine, clinical pharmacology, pharmacometrics
Lead supervisor: Prof. Federico Pea (federico.pea@uniud.it)
ESR 4: Characterizing exposure‐PKPD‐biomarker relationships in special patient populations
Host institution: University of Udine (www.uniud.it)
Planned start of employment: 01-09-2020
Requested background/experience: clinical pharmacology, medicine, pharmacometrics
Lead supervisor: Prof. Federico Pea (federico.pea@uniud.it)
ESR 5: Development and validation of a clinical MBEC assay for individualization of biofilm associated infections
Host institution: Jena University Hospital (www.uniklinikum-jena.de)
Planned start of employment: 01-09-2020
Requested background/experience: medicine, clinical pharmacology, microbiology
Lead supervisor: Prof. Mathias Pletz (Mathias.Pletz@med.uni-jena.de)
ESR 6: Translating clinical susceptibility metrics to mechanistic knowledge to support treatment individualization
Host institution: Leiden University (www.leidenuniv.nl)
Planned start of employment: 01-03-2020 [position filled]
Requested background/experience: pharmacology, microbiology
Lead supervisor: Dr. Coen van Hasselt (coen.vanhasselt@lacdr.leidenuniv.nl)
ESR 8: Establishing PK/PD thresholds based on target site concentrations instead of plasma
Host institution: Medical University of Wien (www.meduniwien.ac.at)
Planned start of employment: 01-09-2020
Requested background/experience: clinical pharmacology
Lead supervisor: Prof. Markus Zeitlinger (markus.zeitlinger@meduniwien.ac.at)
ESR 9: Studies of MICs, biomarkers and PK of ceftazidim‐avibactam (CEF‐AVI) in pneumonia caused by K. pneumoniae
Host institution: Uppsala University (www.uu.se)
Planned start of employment: 01-09-2020
Requested background/experience: medicine, pharmacy, pharmacokinetics, pharmacometrics
Lead supervisors: Prof. Lena Friberg (lena.friberg@farmbio.uu.se); Dr. Elisabeth Nielsen (Elisabet.Nielsen@farmbio.uu.se)
ESR 10: Model‐based translation of antibiotics‐bacteria‐neutrophil interactions in vivo
Host institution: Uppsala University (www.uu.se)
Planned start of employment: 01-09-2020
Requested background/experience: pharmacy, engineering, pharmacokinetics, pharmacometrics
Lead supervisors: Prof. Lena Friberg (lena.friberg@farmbio.uu.se); Dr. Elisabeth Nielsen (Elisabet.Nielsen@farmbio.uu.se)
ESR 11: Biomarkers for early prediction of therapeutic efficacy
Host institution: Paul Ehrlich Institute (www.pei.de)
Planned start of employment: 01-09-2020
Requested background/experience: microbiology, immunology, animal models
Lead supervisor: Prof. Isabelle Bekeredjian-Ding (Isabelle.Bekeredjian-Ding@pei.de)
ESR 12: Influence of species‐specific virulence factors on host response under antibiotic treatment
Host institution: Paul Ehrlich Institute (www.pei.de)
Planned start of employment: 01-09-2020
Requested background/experience: microbiology, immunology, animal models
Lead supervisor: Prof. Isabelle Bekeredjian-Ding (Isabelle.Bekeredjian-Ding@pei.de)
ESR 13: Host response biomarkers for bacterial infections using RNA profiling and Raman spectroscopy
Host institution: Jena University Hospital (www.uniklinikum-jena.de)
Planned start of employment: 01-09-2020
Requested background/experience: medicine, immunology
Lead supervisor: Mathias Pletz (Mathias.Pletz@med.uni-jena.de)
ESR 15 : Systems model for host‐pathogen‐drug interactions to characterize biomarkers and treatment response in bacteremia and sepsis
Host institution: Leiden University (www.leidenuniv.nl)
Planned start of employment: 01-09-2020
Requested background/experience: pharmacology, mathematical modeling, microbiology
Lead supervisor: Dr. Coen van Hasselt (coen.vanhasselt@lacdr.leidenuniv.nl)
Eligibility
At the time of commencing their employment, researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of their (recruiting) host organisation for more than 12 months in the 3 years prior to their recruitment.
Applicants must be in the first four years (full-time equivalent research experience) of their research career and have not been awarded a doctoral degree at the first day of their employment contract. This research experience is measured from the date when they obtain the degree which formally entitles them to embark on a doctorate (either in the country in which the degree was obtained or in the country in which the researcher is recruited), even if a doctorate was never started or envisaged. Research experience is measured to the first day of the employment contract of the researcher.
Usual MSCA eligibility criteria apply and will be verified during the application process. For more information on MSCA, please see: http://ec.europa.eu/mariecurieactions.
Benefits
The successful candidates will receive a 36-month, full-time employment contract as per Marie Skłodowska-Curie Actions (MSCA) regulations for early stage researchers. The monthly salary will be confirmed upon offer, paid in the currency of the host country, and with a correction factor applied to the host country.
In addition to their individual scientific projects, TIPAT ESRs will collaborate with world-leading research groups and industries within the consortium through secondments. All ESRs will benefit from further extensive and varied continuing education, completing a series of carefully designed training modules and transferable skills courses; they will participate in symposia, workshops, and international conferences and will have meaningful exposure to the industrial environment through TIPAT industrial partners.
Application
To apply, please apply through to the individual ESR position description available through hyperlinks for each position in the list of ESR projects above, which is in most case the application webpage for the hosting institute. These local/individual advertisements will have further details including local PhD admission criteria and specific application deadlines and application procedure.
In your application please include the following files:
A motivation letter (1 page maximum), please include in your letter alternative ESR TIPAT positions of interest to you if not selected, if any.
A CV according to the Europass format
Two reference letters (at least one from your Master thesis supervisor)
An up-to-date of grades in your bachelor and master programs
Optional: English proficiency test results (TOEFL, IELTS)
The application deadline is May 20, 2020. We may extend this deadline depending on the developments of the COVID19 pandemic.
The application procedure is as follows:
A notification for receiving your application is send after the application deadline.
Applicants are notified if they are invited for video-conferencing interviews by May 30
Interviews are schedule to be completed by June 15
Hiring process is completed by June 30
Please note these dates may change if the application deadline is extended.