06/03/2019

PhD in Biomedical Engineering - Understanding the interaction between extracellular matrix molecules that modulate tissue turnover


  • ORGANISATION/COMPANY
    University of Melbourne
  • RESEARCH FIELD
    ChemistryBiochemistry
    EngineeringBiomedical engineering
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    31/12/2020 00:00 - Europe/Athens
  • LOCATION
    Australia › Parkville
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/01/2020

OFFER DESCRIPTION

PhD positions are currently available with Dr Brooke Farrugia in the Department of Biomedical Engineering at The University of Melbourne 

 

The Project

The extracellular matrix provides mechanical support and structure to the tissue microenvironment and is assembled from various proteins and glycoproteins, of which collagen and proteoglycans (PGs) are prominent functional components. PGs are decorated with sulphated glycosaminoglycans (GAGs) that are heterogeneous in structure, depending on the cell and tissue type of origin, and vary in a dynamic spatiotemporal manner. The structure of GAGs can be altered by intracellular enzymes before they are secreted, and by enzymes in the extracellular space. Remodelling of the extracellular matrix is a dynamic and ongoing process for many tissues, for which there is a critical interplay between the cells and cues they receive from their surrounding environment.

This project will investigate interactions that occur between the extracellular matrix molecules, collagen and the glycosaminoglycan chondroitin sulphate, to understand the mechanisms that control tissue regeneration and remodelling.

This project would suit a student with a Biochemistry background, or a student that is willing to become familiar and proficient in experimental techniques including, but not limited to cell culture, in vivo models, ELISA, Western Blot, chromatography, PCR,  glycobiology, and CRISPR

 

Application

Applicants must satisfy the requirements to enrol in a graduate research program at the University of Melbourne - for more information on the entry requirements and how to enrol - https://study.unimelb.edu.au/how-to-apply/graduate-research/international-applications

Applicants should also satisfy the requirements and apply for a Graduate Research Scholarship - for more information on eligibility and how to apply - https://scholarships.unimelb.edu.au/awards/graduate-research-scholarships

To be considered as being competitive for a scholarship international students need to have the equivalent of at least 85%. The University of Melbourne calculates their scholarship scores on a case by case basis and primarily using academic transcripts, publications are also taken into consideration, and may marginally increase the score.

All applications for a Graduate Research Scholarship require evidence of support from the research supervisor. Highly motivated candidates who are interested in completing a PhD in Biomedical Engineering and meet the criteria for enrolment are invited to contact Dr Farrugia.

Please email your CV, academic transcript and a brief outline of your previous research experience and your future research goals to brooke.farrugia@unimelb.edu.au 

 

 

More Information

Eligibility criteria

Applicants must satisfy the requirements to enrol in a graduate research program at the University of Melbourne - for more information on the entry requirements and how to enrol - https://study.unimelb.edu.au/how-to-apply/graduate-research/international-applications

Applicants should also satisfy the requirements and apply for a Graduate Research Scholarship - for more information on eligibility and how to apply - https://scholarships.unimelb.edu.au/awards/graduate-research-scholarships

Offer Requirements

Skills/Qualifications

This project would suit a student with a Biochemistry background, or a student that is willing to become familiar and proficient in experimental techniques including, but not limited to cell culture, in vivo models, ELISA, Western Blot, chromatography, PCR, glycobiology, and CRISPR

Specific Requirements

Applicants must have completed 4-year undergrad or Masters (with a research component) degree

Applicants must satisfy the requirements to enrol in a graduate research program at the University of Melbourne - for more information on the entry requirements and how to enrol - https://study.unimelb.edu.au/how-to-apply/graduate-research/international-applications

Applicants should also satisfy the requirements and apply for a Graduate Research Scholarship - for more information on eligibility and how to apply - https://scholarships.unimelb.edu.au/awards/graduate-research-scholarships

To be considered as being competitive for a scholarship international students need to have the equivalent of at least 85%. The University of Melbourne calculates their scholarship scores on a case by case basis and primarily using academic transcripts, publications are also taken into consideration, and may marginally increase the score.

All applications for a Graduate Research Scholarship require evidence of support from the research supervisor. Highly motivated candidates who are interested in completing a PhD in Biomedical Engineering and meet the criteria for enrolment are invited to contact Dr Farrugia.

Map Information

Job Work Location Personal Assistance locations
Work location(s)
3 position(s) available at
University of Melbourne
Australia
Victoria
Parkville
3010

EURAXESS offer ID: 385642

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