- JOB
- Belgium
Job Information
- Organisation/Company
- KU Leuven
- Research Field
- Medical sciences » Medicine
- Researcher Profile
- First Stage Researcher (R1)
- Country
- Belgium
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Hours Per Week
- 38 hours/week
- Is the job funded through the EU Research Framework Programme?
- Not funded by a EU programme
- Reference Number
- BAP-2024-249
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
The complex relationship between epigenetic histone modifications and osteoarthritis (OA) calls for a deeper understanding of histone modifications in healthy and OA-afflicted cartilage. Previous work form our team highlight the key role of histone methyltransferase DOT1L as modulator of Wnt signaling in the disease. However, despite these insights, the precise role of other histone modifications and their interactions in the pathological process from a healthy towards an osteoarthritic joint remain elusive. By performing extensive screens and introducing state-of-the-art technologies such as EpiTOF we identify novel epigenetic factors with likely roles in the disease process. Understanding the mechanisms associated with these histone modifications could unveil novel therapeutic targets, ultimately alleviating OA burden and enhancing patient outcomes.
Where to apply
- Website
Requirements
- Research Field
- Biological sciences
- Education Level
- Master Degree or equivalent
- Languages
- ENGLISH
- Level
- Excellent
- Research Field
- Biological sciences
- Years of Research Experience
- 1 - 4
Additional Information
- A full-time PhD research contract for one year with the possibility to extend (at least) 3 more years thereafter. The position is immediately available. You are stimulated to apply for a predoctoral fellowship.
- The opportunity to work on a high impact, beyond state-of-the-art project with experienced mentors in a successful team.
- We support PhD students with excellent (daily) guidance and training, and provide the opportunity to participate in (inter)national collaborations and conferences.
- A stimulating international, multidisciplinary and dynamic research environment where quality, professionalism and collaborative team spirit are encouraged.
- You have an excellent academic record and hold a Master's degree in any area of biology or biomedical sciences. Candidates who have not yet completed their master's thesis at the time of this application are encouraged to apply.
- Previous laboratory hands-on experience with cell culture and biochemical assays is desired, but not essential. Experience with laboratory animals and holding a Felasa B certificate is also a plus.
- You are a proactive, ambitious, dynamic person and show spirit for initiative and problem-solving. You take great care and precision in your work, and are able to work independently but also as part of a team.
- You have excellent oral and written communication skills in English.
For more information please contact Prof. dr. Rik Lories, tel.: +32 16 37 26 73, mail: rik.lories@kuleuven.be or Prof. dr. Silvia Monteagudo, tel.: +32 16 37 27 34, mail: silvia.monteagudo@kuleuven.be.Please send a copy of your application to silvia.monteagudo@kuleuven.be and rik.lories@kuleuven.be, which should include 1) a full CV including previous research experience 2) a concise cover letter describing your motivation, career objectives and contact details of 2 professional references.
You can apply for this job no later than 01/06/2024 via the online application tool
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- KU Leuven
- Country
- Belgium
- State/Province
- Vlaams Brabant
- City
- Leuven
- Postal Code
- 3000
- Street
- Leuven
- Geofield
Contact
- State/Province
- Leuven
- City
- Vlaams Brabant
- Street
- Leuven
- Postal Code
- 3000
- rik.lories@kuleuven.be