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PhD position in the MSCA Doctoral Network “MobiliTraIN”: Establishing Measurement Standards for Small Molecule Bioanalytical Methods Based on Ion Mobility-Mass Spectrometry

23 Jan 2024

Job Information

Organisation/Company
BOKU Vienna
Department
Chemistry
Research Field
Chemistry » Analytical chemistry
Biological sciences » Biological engineering
Researcher Profile
First Stage Researcher (R1)
Country
Austria
Application Deadline
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
40
Offer Starting Date
Is the job funded through the EU Research Framework Programme?
HE / MSCA
Marie Curie Grant Agreement Number
101119562
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

BOKU Vienna offers a PhD position in the framework of the MSCA Doctoral Network MobiliTraIN(Ion Mobility Mass Spectrometry Training Network). The project aims to bring a new fundamental understanding of ion mobility-high resolution mass spectrometry (IM-HRMS), provide reference materials and guidelines for standardisation, develop state-of-the-art methods for the application of IM-HRMS in biopharmaceutical development, biological omics studies and non-target screening of contaminants, and lay the foundations for the adoption of IM-HRMS in industry by training 13 doctoral candidates.

 

This PhD project (Establishing Measurement Standards for Small Molecule Bioanalytical Methods Based on Ion Mobility-Mass Spectrometry) offered aims to 1) Establish new dedicated measurement standards based on materials of biotechnological origin for broad application in small molecule analysis using commercial and non-commercial IM-HRMS technology; 2) Develop robust procedures for preparation of materials based on new reference samples derived from a recognised industrially relevant yeast (Pichia pastoris); 3) Optimise production of each material to ensure broadest analytical coverage in terms of m/z, CCS, and ensuring applicability within relevant analytical conditions, i.e. polarity, mode of chromatography; 4) Establish the new materials within analytical workflows encompassing a range of small molecule applications across all major commercial IM-HRMS instruments within MobiliTraIN.

 

Secondments: This project is carried out in strong collaboration with the following groups, and visits to their laboratories are expected during the project. A willingness to travel and spend time abroad is therefore essential.

  • Host: BAM, Germany; Length: 3 months; Purpose: Training on standardisation and certification of reference materials.
  • Host: Agilent, USA; Length: 1 month; Purpose: Testing of new extracts and reporting data with Agilent reference instrumentation in R&D environment. 3)
  • Host: FUB, Germany; Length: 3 months; Purpose: Implementation and testing of materials on in-house modified IM-MS instrumentation. Training in computational prediction methods for small molecules.

 

Want to apply?

  • You can apply for this vacancy by email until  30th of April 2024 (deadline extended) by midnight Vienna time. Be sure to include the following attachments:
    • a motivation letter
    • your academic CV
  • We will review all applications as soon as possible after the application deadline. As soon as a decision is made, we will notify you. If you are still eligible after the pre-selection, you will be informed about the next step(s) in the selection procedure.

Requirements

Research Field
Chemistry » Analytical chemistry
Education Level
Master Degree or equivalent
Skills/Qualifications
  • Academic Master recognized by the EU in one of the following disciplines:chemistry, biochemistry, biotechnology or related fields, or you will have obtained it by the time you start work.
  • You can demonstrate excellent academic results from your studies.
  • Knowledge in analytical chemistry, especially in separation sciences and mass spectrometry, and statistics are essential. Hands-on experience in mass spectrometry is an asset.
  • Interest in microbial cell cultivation and willingness to work in a biotechnology laboratory.
  • An organized approach with strong attention to detail.
  • Flexibility and team spirit in an international research environment.
  • Excellent oral and written English communication skills.
  • Willingness to travel internationally for scientific secondments.
Specific Requirements

Candidates must fulfil the MSCA Doctoral Networks Eligibility Criteria stated below.

Specific Eligibility Criteria of the Horizon Europe Marie Sklodowska-Curie (MSCA) programme apply, including the mobility rule and PhD rule. Applicants of any nationality are welcome to apply.

Mobility rule: Researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of the host organisation for more than 12 months in the 3 years immediately before the recruitment date (i.e., the start of employment).

PhD Rule: Applicants must be doctoral candidates, i.e. not already in possession of a doctoral degree at the date of the recruitment.

Languages
ENGLISH
Level
Excellent
Research Field
Chemistry » Analytical chemistry
Years of Research Experience
1 - 4

Additional Information

Benefits

Recruited researchers will be part of the MobililTraIN doctoral programme. MobiliTraIN offers:

  • A thorough scientific education in the frame of a doctoral training programme.
  • The possibility to participate in specific international training courses, workshops and conferences.
  • A strong involvement in a European research project with high international visibility.
  • The possibility to perform research visits to internationally renowned research labs in Europe.
  • A prestigious three-year MSCA Fellowship.

The gross salary per year is €42 945.60. The exact net salary is dependent on local tax and social and health insurance regulations and will be confirmed upon appointment. Moreover, funding is available for technical and personal skills training and participation in international research events.

Find out more about working at BOKU Vienna here

Eligibility criteria
  • Mobility rule: Researchers must not have resided or carried out their main activity (e.g., work, study) in the country of the host organisation for more than 12 months in the 3 years immediately before the recruitment date (i.e., start of employment).
  • PhD rule: Applicants must be doctoral candidates, i.e., must not already be in possession of a doctoral degree at the date of recruitment.

Applicants of all nationalities are welcome to apply.

Selection process
  • We adopt the principles of the European Charter for Researchers and Code of Conduct for the Recruitment of Researchers, promoting open, merit-based and transparent recruitment and attractive working and employment conditions.
  • Following the application by e-mail (first stage), applicants reaching the second stage will be invited for interviews (online).
  • A reserve list of candidates may be kept for up to 6 months.
  • Ineligible or incomplete applications will not be considered.
Website for additional job details

Work Location(s)

Number of offers available
1
Company/Institute
University of Natural Resources and Life Sciences Vienna
Country
Austria
State/Province
Vienna
City
Vienna
Postal Code
1190
Street
Muthgasse 18
Geofield

Where to apply

E-mail
tim.causon@boku.ac.at

Contact

State/Province
Vienna
City
Vienna
Website
Street
Muthgasse 18
Postal Code
1190
E-Mail
tim.causon@boku.ac.at