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EURAXESS Researchers in motion

Job offer

  • JOB
  • Belgium

PhD position – Free steroid hormones in health and disease (FRESH-HD)

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The Human Resources Strategy for Researchers
2 Dec 2023

Job Information

Organisation/Company
KU Leuven
Research Field
Medical sciences » Medicine
Researcher Profile
First Stage Researcher (R1)
Country
Belgium
Application Deadline
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
38 hours/week
Is the job funded through the EU Research Framework Programme?
Not funded by a EU programme
Reference Number
BAP-2023-786
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

In routine clinical practice, diagnosis and treatment of endocrine diseases rely mostly on total steroid hormone levels. However, these hormones typically bind to specific proteins and albumin in circulation, with only a small fraction circulating freely. The 'free hormone hypothesis' proposes that this free fraction is responsible for the biological activity of hormones. Unfortunately, measuring free steroid hormone levels is technically challenging, limiting their implementation in clinical practice.

In our research group, we are dedicated to enhancing the clinical applicability of free steroid hormone concentrations in patients with specific conditions and endocrine diseases. We employ state-of-the-art methodology, particularly mass spectrometry, to investigate the clinical relevance of free steroid hormones.


The main objectives of your research will be:

  • Development, optimization and validation of methods to measure free steroid hormones
  • Investigating binding protein-hormone interactions
  • Studying the interplay between health parameters and free hormones

Requirements

Research Field
Medical sciences
Education Level
Master Degree or equivalent
Languages
ENGLISH
Level
Good

Additional Information

Benefits
Eligibility criteria
  • We are seeking an enthusiastic candidate with a Master's degree in Medicine, Pharmaceutical Sciences, Biomedical Sciences, Rehabilitation Sciences, Bioscience Engineering, Biochemical Engineering Technology or a related field.
  • You should possess a genuine interest in advancing hormone measurements and integrating research findings into clinical practice.
  • Strong communication and organizational skills are essential, along with a keen enthusiasm for collaborating with a diverse range of partners in a multidisciplinary setting.
  • Excellent communication skills in English, both verbal and written.
Selection process

For more information please contact Prof. dr. Leen Antonio, tel.: +32 16 37 27 21, mail: leen.antonio@kuleuven.be.
You can apply for this job no later than 18/12/2023 via the online application tool

Work Location(s)

Number of offers available
1
Company/Institute
KU Leuven
Country
Belgium
State/Province
Vlaams Brabant
City
Leuven
Postal Code
3000
Street
Leuven
Geofield

Contact

State/Province
Leuven
City
Vlaams Brabant
Street
Leuven
Postal Code
3000

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