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23 Nov 2023

Job Information

Organisation/Company
FARM-ID - Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento
Research Field
Pharmacological sciences » Other
Researcher Profile
First Stage Researcher (R1)
Country
Portugal
Application Deadline
Type of Contract
Other
Job Status
Other
Offer Starting Date
Is the job funded through the EU Research Framework Programme?
Not funded by a EU programme
Reference Number
2022.08559.PTDC
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

Under the Regulation of Research Grants of the Foundation for Science and Technology, IP, Regulation No. 950/2019, published in Diário da República, 2nd Series, No. 241, of 16 December, of the Regulation of Research Grants of the University of Lisbon, Dispatch No. 6238/2020, published in Diário da República, 2nd Series, no. 113, of 12 June, republished by Dispatch No. 8061/2022, published in Diário da República, 2nd Series, no. 126, of July 1st, and of the Statute of the Research Fellowship (EBI), Decree-Law no. 123/2019, published in Diário da República, 1st Series, no. 164, of 28 August, it is made known that a call for the award of 1 (one) Research Grantfor Masters enrolled in a non-degree seeking course within the scope of the project 2022.08559.PTDC, titled Merging photochemical and asymmetric synthesis to access new chiral aminocyclopentitols, funded by Foundation for Science and Technology, I.P. (FCT), is open under the following conditions:

Scientific Area: Pharmaceutical Sciences, Chemistry, or related areas

Research Grant Duration: The research will have a duration of 6 months, eventually renewable until the end of the project, starting in January 2024, on an exclusivity regime, in accordance with the terms of the Regulation of Research Grants of the Foundation for Science and Technology, IP.

Work plan: The objective of the work is performed the synthesis of aminocyclopentitol core via photochemical conversion of pyridinium salts under flow conditions to originate diverse bicyclic vinyl aziridines, and their subsequent use in key asymmetric palladium catalyzed C-C bond formation. Optimization of the reaction conditions for Pd-catalyzed asymmetric alkylation of bicyclic vinyl aziridines with Meldrum acid and their application to a number of carbon-based nucleophiles. Appropriate functional group modification of the thus-obtained enantiomerically enriched adducts from the Pd-AAA to reach the desired ACPs. Additionally, is also envisage other reactions of bicyclic vinyl aziridines using Pd-catalysis.

Workplace and Scientific Guidance: The work will be carried out in Building A, Bioorganic Chemistry Laboratory at the premises of the Faculty of Pharmacy of Universidade de Lisboa, under the scientific guidance of under the supervision of Filipa Alexandra Delgado Siopa, Junior Researcher, at the Faculty of Pharmacy of Universidade de Lisboa.                                          

Formalization of applications: Applications must be sent in non-editable format (PDF), to the address concursos@farm-id.pt, containing the identification of the above mentioned notice. Applications in paper format will not be accepted.

Application deadline: The deadline for applications is from 24th November to 11st December 2023 (10 working days).

Requirements

Research Field
Pharmacological sciences » Other
Education Level
Master Degree or equivalent
Skills/Qualifications
  • Demonstrated experience in Synthetic Organic Chemistry, isolation and characterization of organic compounds.
  • Experience in palladium chemistry, C-H activation.
Specific Requirements

Admission Requirements (*):

  • Integrated Master's degree in Pharmaceutical Sciences, or Master's degree in Chemistry or related field;
  • Be enrolled in a non-degree seeking course at the Faculty of Pharmacy, University of Lisbon.

(*) During the application stage, if the candidates do not have in their possession the documents proving their Master´s degree certificate and/or enrolment in the non-degree seeking course, those documents may be replaced by a declaration of honour. The proof of obtaining the degree and/ or enrolment through the presentation of the certificated must be carried out until the hiring, under penalty of annulment of the candidate's assessment due to error on the assumptions of fact, and consequent exclusion from this competition.

Languages
ENGLISH
Level
Excellent
Languages
PORTUGUESE
Level
Excellent

Additional Information

Benefits

Monthly maintenance stipend: The monthly maintenance stipend (grant) corresponds to € 1.199,64, according to the table of values directly attributed by FCT, I.P. in Portugal (https://www.fct.pt/wp-content/uploads/2023/02/Tabela-de-Valores-SMM_2023.pdf). Payment will be made via bank transfer.

In addition to the monthly maintenance stipend the grant holder will also be awarded with the value correspondent to the payment of the first step of Seguro Social Voluntário (voluntary payment of Social Security), in case he/she chooses to be included in this regime.

Eligibility criteria
  1. Form containing the candidate's identification (available on the institutional website);
  2. Curriculum Vitae containing the information necessary for the evaluation of the application;
  3. Proof of obtaining Integrated Master's degree in Pharmaceutical Sciences, or Master's degree in Chemistry, or related field; or declaration under substitutive honour;
  4. Proof of enrolment in the non-degree seeking course or declaration under substitutive honour (available on the institutional website);
  5. Declaration on honour stating that there is no professional activity that violates the exclusivity regime (available on the institutional website);
  6. Letter of motivation;
  7. Other supporting documents considered relevant.

All the documents necessary for the correct application are available on the institutional website trough the link: https://www.ff.ulisboa.pt/faculdade/recursos-humanos/recrutamento/anuncio-para-atribuicao-de-1-uma-bolsa-de-investigacao-mestre-para-estudante-inscrito-em-curso-nao-conferente-de-grau-aviso-n-o-bicncg-23-farm-id-2023

The documents that instruct the application must be submitted in Portuguese or English language.

No document that should have been submitted in the application phase can be submitted after the deadline set in the opening notice. Failure to comply with the deadline set for the submission of the application, as well as the lack or late submission of documents referred to in this point will determine the exclusion from the competition.

Selection process

Candidate's Merit: Aims to assess compliance with the formal requirements requested in the opening notice, but also to consider the suitability of the scientific area of training and/or specialization, training and professional experience, with a maximum weighting of 100%.

Adequacy of the Scientific Training Area (AACF): Candidates will be ranked on the basis of holding a Master's degree in Pharmaceutical Sciences or related field with a maximum weighting of 30%.

Training and Experience (FE): Candidates will be ranked on the basis of laboratory experience in synthetic organic chemistry, including palladium chemistry, C-H activation, isolation and characterisation of organic compounds, with a maximum weighting of 40%.

Specific competencies for the proposed work plan (CEPTP): Applicants will be screened on the basis of knowledge in synthetic organic chemistry and structural analysis, and a good command of the English language, spoken and written, with a maximum weighting of 30%.

If case it proves necessary, an individual interview will be held with the 5 (five) best candidates, in which case the interview will not be scored or will it have weight in the Final classification, and will only serve to clarify the information.

Final Classification: The score obtained in the final classification results from the sum of the points obtained in the Candidate's Merit, an individual form being out for each candidate.

 

The Jury responsible for the selection will be constituted by:

President - Filipa Alexandra Delgado Siopa, Junior Researcher, FFUL

1st Member of the Jury - Carlos Alberto Mateus Afonso, Full Professor, FFUL

2nd Member of the Jury - Jaime Alfredo da Silva Coelho, Auxiliary Researcher, FCUL.

1st Alternate Member of the Jury Pedro Miguel Pimenta Góis, Assistant Professor with habilitation, FFUL.

2nd Alternate Member of the Jury - Andreia Almeida Rosatella, Junior Researcher, University Lusófona.

Additional comments

Form of notification of results: All candidates will be notified of the final results of the evaluation by email, and will have 10 working days after the aforementioned notification to say something, in accordance with the terms of the Code of Administrative Procedure.

After this notification, and in case there are no claims, the results will become final. In case of claims, and after the allegation is analysed and accepted or rejected, the results will become final after 10 business days.

After the final decision is made, a complaint/appeal can be filed to the Director of the FARM-ID – Faculty of Pharmacy Research and Development Association, Maria Beatriz da Silva Lima, PhD, Full Professor, within 10 working days from the date of notification.

Applicable legislation and regulations: Regulation of Research Grants of the Foundation for Science and Technology, I.P. (FCT, IP), Regulation no. 950/2019, published in the Diário da República, 2nd Series, no. 241, of December 16, 2019, of the Regulation of Research Grants of the University of Lisbon, Order no. 6238/2020, of 12 June, republished by Order no. 8061/2022, published in the Diário da República, 2nd Series, no. 113, of 12 June 2020, and of the Research Fellowship Statute (EBI), Decree-Law no. 123/2019, of 28 August, published in Diário da República, 1st Series, no. 164, of 28 August 2019.

Website for additional job details

Work Location(s)

Number of offers available
1
Company/Institute
FARM-ID - Associação da Faculdade de Farmácia para a Investigação e Desenvolvimento
Country
Portugal
Geofield

Contact

City
Lisboa
Website
Street
Av. Prof. Gama Pinto
Postal Code
1649-003
E-Mail
rh@farm-id.pt
Phone
217946400

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