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EURAXESS Researchers in motion

Job offer

Universitat de Barcelona
  • JOB
  • Spain

Molecular bases of chemical cooperativity in ternary complexes of therapeutic interest

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The Human Resources Strategy for Researchers
31 Oct 2023

Job Information

Organisation/Company
Universitat de Barcelona
Department
Organisation profile
Research Field
Pharmacological sciences
Researcher Profile
First Stage Researcher (R1)
Country
Spain
Application Deadline
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
37,5
Offer Starting Date
Is the job funded through the EU Research Framework Programme?
Not funded by a EU programme
Reference Number
PRE04/2023_IP J. JUAREZ
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

Computer Aided Design of Molecular Glues (CAD-MG)

We are seeking a very motivated PhD candidate to join the Computational Biology and Drug Discovery group under the joint supervision of Prof. Curutchet and Dr. Juárez-Jiménez. The successful candidate will be expected to carry out common Computer Aided Drug Design task within the framework of the discovery of novel therapeutic and biotechnological strategies. Of particular interest for this call is the development of small molecules able to stabilize protein-protein interactions in the context of targeted protein degradation and other systems of interest. The specific tasks to be developed include:

  • Set up and analysis of virtual screening campaigns of commercial libraries of bioactive compounds.
  • Set up and analysis of Molecular Dynamics simulations, including enhanced sampling techniques, to study binary and ternary complexes of potential therapeutic and biotechnological interest.
  • Development and application of machine learning models to accelerate the discovery of new bioactive molecules of potential therapeutic and biotechnological interest.
  • Tasks associated to the dissemination of research outcomes, including the preparation of scientific articles and conference presentations.  

Requirements

Research Field
Pharmacological sciences
Education Level
Master Degree or equivalent
Skills/Qualifications

Hold a BSc/MSc in Pharmacy or Chemistry and fulfil the requirements to be admitted into the Biotechnology PhD program at the Universitat de Barcelona.

https://www.ub.edu/escoladoctorat/en/access-and-admission/access-pathwa…

Indicar el que correspongui, si escau.

Specific Requirements
  • To be familiar with the Drug Discovery Process.
  • Knwoledge about the molecular bases of oncological and neurodegenerative diseases

Previous experience in the application of computational techniques to the design of bioactive molecules. 

Languages
CATALAN
Level
Excellent
Languages
SPANISH
Level
Excellent
Languages
ENGLISH
Level
Excellent
Research Field
ChemistryPharmacological sciences
Years of Research Experience
None
Internal Application form(s) needed
5_Sollicitud_declaracio_responsable_0.pdf
English
(254.6 KB - PDF)
Download

Additional Information

Benefits

17.651,76 first annuity

A full-time work contract (37.5 hrs/week). The researcher will have the possibility to participate in teaching activities for professional development (not obligatory, though)

Eligibility criteria

A specific committee will evaluate the applications using the following criteria:

  • Grade point average of the academic transcripts from the applicant's bachelor's or master's degree studies (or 1st and 2nd cycle): up to 5 points out of a total of 10.
  • Curricular merits: up to 1 point out of a total of 10 in accordance with the specific criteria listed in Annex 1.
  • Suitability for the tasks to be performed within the framework of the research project or research support position to which the successful candidate will be attached: up to 4 points out of a total of 10.
Selection process

The specific committee will agree upon an award proposal and draw up a prioritized shortlist of candidates who have achieved a minimum of five points or declare the call for applications null and void if none of the applicants reach the minimum score.

The award proposal will be published in the UB's electronic office and must include the total scores of the candidates that have received a total of at least five points.

 

Application Process:

According to the specific requirements and selection criteria, the candidates are expected to provide at least the following documents:

 

•   Application form

  • Full CV

•    BSc and MSc academic transcripts

 

Additional comments

The candidate proposed for hiring must accept the job offer within 5 working days from the date of notification of the selection.

Be aware that the starting date sets in this offer is an estimate date. The official starting date will depend on the time necessary for administration to prepare the labour contract and present the necessary documents for the selected candidate to be hired.

 

Priority will be given to people with disabilities (Law 89/2015 of June 2, reserve of quota 2% in favour of people with disabilities in companies of 50 or more people).

Website for additional job details

Work Location(s)

Number of offers available
1
Company/Institute
Pharmacy and pharmaceutical Technology, and Physical Chemistry
Country
Spain
State/Province
Barcelona
City
Barcelona
Postal Code
08028
Street
Av. Joan XXIII, 27-31
Geofield
Number of offers available
1
Company/Institute
Institute of Theoretical and Computational Chemistry – University of Barcelona
Country
Spain
State/Province
Barcelona
City
Barcelona
Postal Code
08028
Street
Av. Joan XXIII, 27-31

Contact

State/Province
Barcelona
City
Barcelona
Website
Street
Gran Via de les Corts Catalanes, 585
Postal Code
08007
E-Mail
carles.curutchet@ub.edu

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