- JOB
- Spain
Job Information
- Organisation/Company
- Universitat de Barcelona
- Department
- Organisation profile
- Research Field
- Pharmacological sciences
- Researcher Profile
- First Stage Researcher (R1)
- Country
- Spain
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Hours Per Week
- 37,5
- Offer Starting Date
- Is the job funded through the EU Research Framework Programme?
- Not funded by a EU programme
- Reference Number
- PRE04/2023_IP J. JUAREZ
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
Computer Aided Design of Molecular Glues (CAD-MG)
We are seeking a very motivated PhD candidate to join the Computational Biology and Drug Discovery group under the joint supervision of Prof. Curutchet and Dr. Juárez-Jiménez. The successful candidate will be expected to carry out common Computer Aided Drug Design task within the framework of the discovery of novel therapeutic and biotechnological strategies. Of particular interest for this call is the development of small molecules able to stabilize protein-protein interactions in the context of targeted protein degradation and other systems of interest. The specific tasks to be developed include:
- Set up and analysis of virtual screening campaigns of commercial libraries of bioactive compounds.
- Set up and analysis of Molecular Dynamics simulations, including enhanced sampling techniques, to study binary and ternary complexes of potential therapeutic and biotechnological interest.
- Development and application of machine learning models to accelerate the discovery of new bioactive molecules of potential therapeutic and biotechnological interest.
- Tasks associated to the dissemination of research outcomes, including the preparation of scientific articles and conference presentations.
Where to apply
- Website
Requirements
- Research Field
- Pharmacological sciences
- Education Level
- Master Degree or equivalent
Hold a BSc/MSc in Pharmacy or Chemistry and fulfil the requirements to be admitted into the Biotechnology PhD program at the Universitat de Barcelona.
https://www.ub.edu/escoladoctorat/en/access-and-admission/access-pathwa…
Indicar el que correspongui, si escau.
- To be familiar with the Drug Discovery Process.
- Knwoledge about the molecular bases of oncological and neurodegenerative diseases
Previous experience in the application of computational techniques to the design of bioactive molecules.
- Languages
- CATALAN
- Level
- Excellent
- Languages
- SPANISH
- Level
- Excellent
- Languages
- ENGLISH
- Level
- Excellent
- Research Field
- ChemistryPharmacological sciences
- Years of Research Experience
- None
Additional Information
17.651,76 first annuity
A full-time work contract (37.5 hrs/week). The researcher will have the possibility to participate in teaching activities for professional development (not obligatory, though)
A specific committee will evaluate the applications using the following criteria:
- Grade point average of the academic transcripts from the applicant's bachelor's or master's degree studies (or 1st and 2nd cycle): up to 5 points out of a total of 10.
- Curricular merits: up to 1 point out of a total of 10 in accordance with the specific criteria listed in Annex 1.
- Suitability for the tasks to be performed within the framework of the research project or research support position to which the successful candidate will be attached: up to 4 points out of a total of 10.
The specific committee will agree upon an award proposal and draw up a prioritized shortlist of candidates who have achieved a minimum of five points or declare the call for applications null and void if none of the applicants reach the minimum score.
The award proposal will be published in the UB's electronic office and must include the total scores of the candidates that have received a total of at least five points.
Application Process:
According to the specific requirements and selection criteria, the candidates are expected to provide at least the following documents:
• Application form
- Full CV
• BSc and MSc academic transcripts
The candidate proposed for hiring must accept the job offer within 5 working days from the date of notification of the selection.
Be aware that the starting date sets in this offer is an estimate date. The official starting date will depend on the time necessary for administration to prepare the labour contract and present the necessary documents for the selected candidate to be hired.
Priority will be given to people with disabilities (Law 89/2015 of June 2, reserve of quota 2% in favour of people with disabilities in companies of 50 or more people).
- Website for additional job details
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Pharmacy and pharmaceutical Technology, and Physical Chemistry
- Country
- Spain
- State/Province
- Barcelona
- City
- Barcelona
- Postal Code
- 08028
- Street
- Av. Joan XXIII, 27-31
- Geofield
- Number of offers available
- 1
- Company/Institute
- Institute of Theoretical and Computational Chemistry – University of Barcelona
- Country
- Spain
- State/Province
- Barcelona
- City
- Barcelona
- Postal Code
- 08028
- Street
- Av. Joan XXIII, 27-31
Contact
- State/Province
- Barcelona
- City
- Barcelona
- Website
- Street
- Gran Via de les Corts Catalanes, 585
- Postal Code
- 08007
- carles.curutchet@ub.edu