Application Deadline: 13 December 2019
Translational SYStemics (TranSYS) - Personalized Medicine at the Interface of Translational Research and Systems Medicine at KU Leuven has 9 PhD research positions available:
- ESR 1 (KU Leuven Belgium): "Development of individual-specific molecular networks" at the KU Leuven/Leuven University (Belgium)
- ESR 2 (KU Leuven Belgium): "Hunting for patient subtypes through image-based phenotypes as biomarkers for major gene effects in medical disorders" at the KU Leuven/Leuven University (Belgium)
- ESR3: "GDPR regulation in translational medicineMain" at the Erasmus Universitair Medisch Centrum Rotterdam (Netherlands)
- ESR 5: "Personalized molecular signatures for modulatingprogression of metabolic liver disease (NAFLD) to hepatocellular carcinoma" at the Univerza V Ljublani (Slovenia)
- ESR 6: "Dissecting cellular heterogeneity of Parkinson’s disease (PD) related iPS cells during aging by integrated single cell transcriptomics and imaging analysis to identify disease modifiers" at the Université Du Luxembourg (Luxembourg),
- ESR 7: "Personalized approaches to modulate tumor behavior using vitamin D3" at the Fundacion Centro Nacional de Investigaciones Oncologogicas Carlos III (Spain),
- ESR 9: "Patient-centric data integration framework for highly dimensional data" at the Barcelona Supercomputing Center (Spain),
- ESR 11: "Identification of biological subtypes related to treatment resistant depression" at the Biomax Informatics ag, (Germany)
- ESR 12: "Multi-omics analysis to delineate drug-response pathways" at the Universitair Medisch Centrum Groningen (Netherlands)
TranSYS, coordinated by K. Van Steen (KU Leuven), will recruit 15 ESRs (Early Stage Researchers) to highly skilled jobs in the new area of Systems Health developing tools and approaches to exploit large and complex datasets, to advance Precision (Personalised) Medicine in several disease areas.
The training programme and experience of different international research environments cuts across traditional data and life sciences silos. The emphasis on translational research will support new collaborations between academics and the pharma and health analytics sectors.
Our ESR projects will advance the state of the art on biomarker discovery, improve understanding of disease-specific molecular mechanism and target identification for optimal diagnostics, disease risk and treatment management, refine data generation and their management (including warehousing, disease specific and standardised approaches for data processing, visualisation and model development) leading to improved clinical study design, clinical sampling and more targeted therapeutics.
This ETN (European Training Network) will internationalise participants, and leverage EC (European Commission) and industry sponsorship, to structure and expand the unique training programme and advance emerging research areas, combining wet-lab, clinical and Big Data resources with computational and modelling know-how.
To achieve a paradigm shift in research training this ETN brings together international leaders in Preclinical Science & Molecular Medicine, Systems Analytics, and Targeted Therapeutics, from academia and industry. These experts are ideally positioned to develop the proposed training programme and deliver a highly-trained workforce of next generation scientists, with the right mind-set, knowledge and skills, at the interface of Translational and Systems Medicine. The TranSYS training programme is designed to addresses a critical skills gaps that is currently a bottle- neck to advancing Precision Medicine.