Job Information
- Organisation/Company
- Institute of Physical Chemistry, Polish Academy of Sciences
- Department
- Dioscuri Centre for Physics and Chemistry of Bacteria
- Research Field
- Biological sciencesBiological sciences » Biological engineeringBiological sciences » BiologyBiological sciences » OtherChemistryChemistry » Physical chemistryEngineeringEngineering » Biomedical engineeringEngineering » MicroengineeringPhysicsPhysics » OpticsPhysics » ElectronicsPhysics » Condensed matter propertiesPhysics » BiophysicsPhysics » Applied physics
- Researcher Profile
- Recognised Researcher (R2)
- Country
- Poland
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Hours Per Week
- 40
- Is the job funded through the EU Research Framework Programme?
- Not funded by an EU programme
- Reference Number
- Rekrutacja nr 53/2022
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
About the Dioscuri Centre
The Centre’s main objective is to better understand bacterial growth and evolution in the natural environment of pathogenic bacteria: the interior of an animal cell and animal secretions. The members of the Centre use experimental in vitro models of infections, computer simulations and mathematical theory to create data driven, quantitative models of bacterial growth and evolution in these environments. Research performed in the Centre will contribute towards the understanding of bacterial infections and the evolution of antimicrobial resistance (AMR) in animal and human hosts. The Centre collaborates with research institutions in Germany, the UK and the US. The Centre is co-funded by the Polish Ministry of Science and Higher Education and the German Federal Ministry of Education and Research, with additional support coming from NAWA.
The Centre is located in the Institute for Physical Chemistry (IPC, Polish: IChF), Polish Academy of Sciences, Warsaw, Poland.
Job purpose:
We seek two post-doctoral researchers: one with experience in optical imaging and/or microfluidics, and another one in microbiology, genetic engineering of bacteria and whole-genome sequencing to contribute to the project “Transition from genetic to phenotypic antibiotic resistance in de novo bacterial mutants”.
The project will involve (i) genetic engineering of E. coli strains to enable CRISPR/Cas9-based imaging of de novo mutations in live bacterial cells, (ii) designing and creating a microfluidic device suitable for live imaging of 1 billion bacterial cells, (iii) tracking antibiotic-resistant spontaneous mutants that evolve in the device, measuring their growth rate over several generations, and sequencing their DNA to reveal the nature of genetic alterations. Other team members will use mathematical modelling to interpret the data and predict the effect of the genotype-to phenotype transition on the dynamics of bacterial infections.
Main responsibilities:
1. Planning and execution of specific elements of the research program, acting under general guidance of the supervisor. This will involve deciding (with the supervisor) on the detailed direction of the research, formulating a strategy for day-to-day research work, implementing the strategy (without close supervision), interpreting obtained data, drawing conclusions, and reporting progress to the supervisor.
2. Communicating research results to team members and collaborators at IPC and other institutions through talks and discussions, as well as learning about others’ research through seminars and journal clubs.
3. Assisting with supervision of junior researchers (Master and PhD students), where appropriate.
4. Writing reports and scientific papers.
5. Attending and presenting at workshops and conferences.
6. Keeping up-to-date with relevant scientific developments through literature review.
Career perspectives
The position is initially for 1 year, after which it may be extended for another 2 years (maximum total duration 3 years) subject to satisfactory performance
Requirements
- Research Field
- Physics
- Education Level
- Master Degree or equivalent
- Research Field
- Chemistry
- Education Level
- Master Degree or equivalent
- Research Field
- Engineering
- Education Level
- Master Degree or equivalent
Essential
• PhD held or to be completed before the job start date in physics, chemistry, microbiology, or bioengineering.
• Hands-on experience in optical imaging and/or microfluidics, including image analysis (ImageJ, Python, or Matlab) OR expertise in microbiology and genetic engineering of E. coli
• Very good academic achievements as evidenced by peer-reviewed publications and talks/poster presentations at international conferences.
• Ability to draft (in English) scientific papers for academic journals.
• Ability to communicate (in English) complex information clearly, orally and in writing.
• Ability to think creatively, propose and develop new ideas.
• Capability of working without close supervision, exercising a high degree of initiative and demonstrating a pro-active approach to work.
• Ability to develop and maintain effective working relationships.
• Enthusiasm for learning basic microbiology techniques.
Desirable
• Experience in developing DIY microscopes or other optical imaging devices OR experience with CRISPR/Cas9
• Experience with automated epi-fluorescent microscopes and Micromanager (software for controlling microscopes)
• Microfluidics experience
• Experience with software for designing microfluidic chips such as AutoCAD OR experience with DNA sequencing (DNA isolation, library prep, variant calling).
• Experience in cross-disciplinary and / or collaborative research projects.
• Ability to communicate with researchers with different scientific backgrounds.
• Ability to adapt to new ideas and willingness to approach new challenges and adjust plans to suit new priorities.
• Ability to work hard and organise work so as to perform multiple tasks simultaneously.
• Ability to maintain a clean and well-organised laboratory environment and to set up and maintain a well-organised digital repository of experimental data and protocols.
• Potential for career advancement as an independent researcher.
Post-doc (<7 years since PhD as of 1 Jan 2023. Extensions possible due to maternity or sick leave)
- Languages
- ENGLISH
- Level
- Excellent
- Research Field
- Physics
- Years of Research Experience
- 1 - 4
- Research Field
- Chemistry
- Years of Research Experience
- 1 - 4
- Research Field
- Engineering
- Years of Research Experience
- 1 - 4
Additional Information
Gross salary 11000 PLN/month (net salary approx. 8700 PLN, approximately 1800 EUR), private healthcare
see Skills/qualifications above
A complete application should include the following items:
• motivation letter
• professional curriculum vitae
• list of publications
• personal data processing consent
• in addition, letters of reference may be provided, though this is not obligatory
All documents (including the reference letters) should be emailed to rekrutacja@ichf.edu.pl
Short-listed candidates will be invited for an in-person interview or a conference call (Zoom or Skype) in January 2023
By submitting the application you consent to the processing of your personal data in the recruitment process.
The controller of your personal data is the Institute of Physical Chemistry of the Polish Academy of Sciences with its registered office in Warsaw, NIP: 5250008755 (the "Institute"). The Institute will process your data for the purpose of carrying out scientific and research activities, providing services and contact with the Institute, on the basis of a contract (in connection with the performance of the contract or in order to take action on your request before the contract is concluded – Article 6, paragraph 1, letter b) of GDPR), the legitimate interest of the Institute (Article 6, paragraph 1, letter f) of the GDPR) and legal provisions (Article 6, paragraph 1, letter c) of the GDPR) - depending on the circumstances.
You have the right to: request access to your data, receive a copy of it; rectify (correct) it; delete it; limit its processing; transfer it; lodge a complaint to the supervisory body; withdraw your consent for processing at any time (withdrawal of consent does not affect the lawfulness of the processing carried out prior to its withdrawal) or to lodge an objection to data processing. More information is available on the Institute's website.
https://ichf.edu.pl/theme/ichf/pliki/RODO_klauzula_informacyjna.pdf
Work Location(s)
- Number of offers available
- 2
- Company/Institute
- Institute of Physical Chemistry, Polish Academy of Sciences
- Country
- Poland
- City
- Warsaw
- Postal Code
- PL-01-224
- Street
- Warsaw, Kasprzaka 44/52
- Geofield
Where to apply
- rekrutacja@ichf.edu.pl
Contact
- City
- Warsaw
- Website
- Street
- Warsaw, Kasprzaka 44/52
- Postal Code
- PL-01-224
- bwaclaw@ichf.edu.pl
- Phone
- +48 22 343 21 70