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EURAXESS

Two post-doctoral positions in biology/biological physics

Institute of Physical Chemistry, Polish Academy of Sciences The Human Resources Strategy for Researchers
29 Nov 2022

Job Information

Organisation/Company
Institute of Physical Chemistry, Polish Academy of Sciences
Department
Dioscuri Centre for Physics and Chemistry of Bacteria
Research Field
Biological sciences
Biological sciences » Biological engineering
Biological sciences » Biology
Biological sciences » Other
Chemistry
Chemistry » Physical chemistry
Engineering
Engineering » Biomedical engineering
Engineering » Microengineering
Physics
Physics » Optics
Physics » Electronics
Physics » Condensed matter properties
Physics » Biophysics
Physics » Applied physics
Researcher Profile
Recognised Researcher (R2)
Country
Poland
Application Deadline
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
40
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Reference Number
Rekrutacja nr 53/2022
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

About the Dioscuri Centre

The Centre’s main objective is to better understand bacterial growth and evolution in the natural environment of pathogenic bacteria: the interior of an animal cell and animal secretions. The members of the Centre use experimental in vitro models of infections, computer simulations and mathematical theory to create data driven, quantitative models of bacterial growth and evolution in these environments. Research performed in the Centre will contribute towards the understanding of bacterial infections and the evolution of antimicrobial resistance (AMR) in animal and human hosts. The Centre collaborates with research institutions in Germany, the UK and the US. The Centre is co-funded by the Polish Ministry of Science and Higher Education and the German Federal Ministry of Education and Research, with additional support coming from NAWA.

The Centre is located in the Institute for Physical Chemistry (IPC, Polish: IChF), Polish Academy of Sciences, Warsaw, Poland.

 

Job purpose:

We seek two post-doctoral researchers: one with experience in optical imaging and/or microfluidics, and another one in microbiology, genetic engineering of bacteria and whole-genome sequencing to contribute to the project “Transition from genetic to phenotypic antibiotic resistance in de novo bacterial mutants”.

The project will involve (i) genetic engineering of E. coli strains to enable CRISPR/Cas9-based imaging of de novo mutations in live bacterial cells, (ii) designing and creating a microfluidic device suitable for live imaging of 1 billion bacterial cells, (iii) tracking antibiotic-resistant spontaneous mutants that evolve in the device, measuring their growth rate over several generations, and sequencing their DNA to reveal the nature of genetic alterations. Other team members will use mathematical modelling to interpret the data and predict the effect of the genotype-to phenotype transition on the dynamics of bacterial infections.

Main responsibilities:

1. Planning and execution of specific elements of the research program, acting under general guidance of the supervisor. This will involve deciding (with the supervisor) on the detailed direction of the research, formulating a strategy for day-to-day research work, implementing the strategy (without close supervision), interpreting obtained data, drawing conclusions, and reporting progress to the supervisor.

2. Communicating research results to team members and collaborators at IPC and other institutions through talks and discussions, as well as learning about others’ research through seminars and journal clubs.

3. Assisting with supervision of junior researchers (Master and PhD students), where appropriate.

4. Writing reports and scientific papers.

5. Attending and presenting at workshops and conferences.

6. Keeping up-to-date with relevant scientific developments through literature review.

 

Career perspectives

The position is initially for 1 year, after which it may be extended for another 2 years (maximum total duration 3 years) subject to satisfactory performance

Requirements

Research Field
Physics
Education Level
Master Degree or equivalent
Research Field
Chemistry
Education Level
Master Degree or equivalent
Research Field
Engineering
Education Level
Master Degree or equivalent
Skills/Qualifications

Essential

• PhD held or to be completed before the job start date in physics, chemistry, microbiology, or bioengineering.

• Hands-on experience in optical imaging and/or microfluidics, including image analysis (ImageJ, Python, or Matlab) OR expertise in microbiology and genetic engineering of E. coli

• Very good academic achievements as evidenced by peer-reviewed publications and talks/poster presentations at international conferences.

• Ability to draft (in English) scientific papers for academic journals.

• Ability to communicate (in English) complex information clearly, orally and in writing.

• Ability to think creatively, propose and develop new ideas.

• Capability of working without close supervision, exercising a high degree of initiative and demonstrating a pro-active approach to work.

• Ability to develop and maintain effective working relationships.

• Enthusiasm for learning basic microbiology techniques.

Desirable

• Experience in developing DIY microscopes or other optical imaging devices OR experience with CRISPR/Cas9

• Experience with automated epi-fluorescent microscopes and Micromanager (software for controlling microscopes)

• Microfluidics experience

• Experience with software for designing microfluidic chips such as AutoCAD OR experience with DNA sequencing (DNA isolation, library prep, variant calling).

• Experience in cross-disciplinary and / or collaborative research projects.

• Ability to communicate with researchers with different scientific backgrounds.

• Ability to adapt to new ideas and willingness to approach new challenges and adjust plans to suit new priorities.

• Ability to work hard and organise work so as to perform multiple tasks simultaneously.

• Ability to maintain a clean and well-organised laboratory environment and to set up and maintain a well-organised digital repository of experimental data and protocols.

• Potential for career advancement as an independent researcher.

Specific Requirements

Post-doc (<7 years since PhD as of 1 Jan 2023. Extensions possible due to maternity or sick leave)

Languages
ENGLISH
Level
Excellent
Research Field
Physics
Years of Research Experience
1 - 4
Research Field
Chemistry
Years of Research Experience
1 - 4
Research Field
Engineering
Years of Research Experience
1 - 4

Additional Information

Benefits

Gross salary 11000 PLN/month (net salary approx. 8700 PLN, approximately 1800 EUR), private healthcare

Eligibility criteria

see Skills/qualifications above

Selection process

A complete application should include the following items:

• motivation letter

• professional curriculum vitae

• list of publications

• personal data processing consent

• in addition, letters of reference may be provided, though this is not obligatory

All documents (including the reference letters) should be emailed to rekrutacja@ichf.edu.pl

Additional comments

Short-listed candidates will be invited for an in-person interview or a conference call (Zoom or Skype) in January 2023

 

By submitting the application you consent to the processing of your personal data in the recruitment process.

The controller of your personal data is the Institute of Physical Chemistry of the Polish Academy of Sciences with its registered office in Warsaw, NIP: 5250008755 (the "Institute"). The Institute will process your data for the purpose of carrying out scientific and research activities, providing services and contact with the Institute, on the basis of a contract (in connection with the performance of the contract or in order to take action on your request before the contract is concluded – Article 6, paragraph 1, letter b) of GDPR), the legitimate interest of the Institute (Article 6, paragraph 1, letter f) of the GDPR) and legal provisions (Article 6, paragraph 1, letter c) of the GDPR) - depending on the circumstances.

You have the right to: request access to your data, receive a copy of it; rectify (correct) it; delete it; limit its processing; transfer it; lodge a complaint to the supervisory body; withdraw your consent for processing at any time (withdrawal of consent does not affect the lawfulness of the processing carried out prior to its withdrawal) or to lodge an objection to data processing. More information is available on the Institute's website.

https://ichf.edu.pl/theme/ichf/pliki/RODO_klauzula_informacyjna.pdf

Work Location(s)

Number of offers available
2
Company/Institute
Institute of Physical Chemistry, Polish Academy of Sciences
Country
Poland
City
Warsaw
Postal Code
PL-01-224
Street
Warsaw, Kasprzaka 44/52
Geofield

Where to apply

E-mail
rekrutacja@ichf.edu.pl

Contact

City
Warsaw
Website
Street
Warsaw, Kasprzaka 44/52
Postal Code
PL-01-224
E-Mail
bwaclaw@ichf.edu.pl
Phone
+48 22 343 21 70