Job Information
- Organisation/Company
- Utrecht University
- Research Field
- Medical sciences » Veterinary medicineBiological sciences » Biological engineering
- Researcher Profile
- First Stage Researcher (R1)
- Country
- Netherlands
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Hours Per Week
- 40
- Offer Starting Date
- Is the job funded through the EU Research Framework Programme?
- HE / MSCA
- Marie Curie Grant Agreement Number
- 101073263
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
Are you looking for a high impact PhD position in close collaboration with industry?
The European Doctoral Network ‘SSBB’ now offers a fully funded industrial PhD student position in the area of novel antimicrobial approaches to combat multidrug resistant bacteria, starting between 1 June and 1 September 2023. We offer a 4-year full-time position to generate and test a new generation of antibiotics, so-called non-digestible oligosaccharides (NDOs) or antimicrobial peptides (AMPs). This project is part of the Doctoral Network Stop Spread Bad Bugs (SSBB) funded by Horizon Europe-MSCA. The successful candidate will be hosted at Utrecht University, the Netherlands, and at Anitom, Belgium.
SSBB is focused on the discovery of novel antimicrobial approaches to reduce multidrug resistant bacteria. The consortium consists of 14 leading European R&D laboratories from universities, industries, and technology institutes in the domain of drug development, infectiology, immunology and pharmacology, which are located in Austria, Belgium, Germany, Ireland, Italy, The Netherlands, Norway, Spain and Switzerland. SSBB will provide the Doctoral Candidates (DCs) with a comprehensive set of theoretical and practical skills relevant for innovation and long-term employability in a rapidly growing sector. This highly innovative training will cover several inter-disciplinary areas. Each PhD student will be enrolled in a doctoral program and will have two official employers, one from academia and one from industry. Highly qualified personnel from both employers will jointly coach the PhD student.
The aim of this specific doctoral program (DC12) is to investigate whether certain NDOs or AMPs exhibit anti-infective effects on pathogenic respiratory and gastro-intestinal bacteria and hence support the “healthy” diversity of gut microbiota in poultry. To test the anti-infective effects of antimicrobial compounds, conventionally hatched broilers will be infected with Avian PathogenicE. Coli in a controlled experimental floor pen trial. Antimicrobial compounds will be administrated (orally or via the respiratory system e.g. aerosol/ intra-tracheal) and the effects will be evaluated by examining the health of the broilers, zootechnical performance, the microbiome and immune system.
WHO WE ARE
Utrecht University (UU) will be the main host, more specifically the doctoral candidate will be employed at the division of pharmacology at the Utrecht Institute for Pharmaceutical Sciences. The DC will be supervised by Prof. Dr. Gert Folkerts, a full-time professor at UU, focusing on in vivo pharmacology and translational research. Dr. Saskia Braber, assistent professor with expertise in inflammation, pharmacology, immunology, and chronic diseases will be the daily supervisor at UU.
The co-host is Anitom, a research organisation specialized in research and innovations in livestock. Anitom has a broiler facility in Sint-Truiden (Belgium), where trials for this doctoral program will be performed. Dr. Anniek Bus, veterinarian and experienced in animal trials will act as daily supervisor at Anitom.
JOB DESCRIPTION
The objective of the DC12 project is to determine the potency of selected antimicrobial compounds to dampen gastro-intestinal infections in-vivo. The DC12 will test the anti-infective effects of the new antimicrobial compounds by an infection model used in conventionally hatched broilers in a controlled experimental floor pen trial. New antimicrobial compounds will be administered and the effects on health, zootechnical parameters, the microbiome, and the immune system will be evaluated.
Requirements
- Research Field
- Medical sciences » Veterinary medicine
- Education Level
- Master Degree or equivalent
- Research Field
- Biological sciences » Biological engineering
- Education Level
- Master Degree or equivalent
Applicants should have/expect to receive, the MSc degree or equivalent in Veterinary Sciences, Bioscience Engineering, Biomedical Sciences, Animal Sciences and related disciplines and should not have more than four years of research experience. Applicants must possess a Master of Science Degree issued by an officially recognized academic institution.
Besides good subject knowledge, emphasis will be on creative thinking, motivation, ability to cooperate, initiative to work independently and personal suitability for research training. Experience or interest in livestock (poultry industry) is a plus.
If you are interested in this PhD position, please apply by using email indicated below. You must upload the following documents (PDF format only):
- Cover letter, explaining your motivation for applying and how you meet the job requirements (1 A4 page maximum);
- A detailed Curriculum Vitae, including also a list of publications, awards and contact information of two referees;
- Copies of diplomas, including list of courses taken and grades obtained;
- Proof of English language skills (if you are not a native speaker);
- Any other information you deem relevant (e.g. PDF of a recent paper).
- Languages
- ENGLISH
- Level
- Good
Additional Information
4-year full-time employment contract will be issued. The first 3 years are in accordance with the Marie Skłodowska-Curie Action (MSCA) regulations for Doctoral Candidates; The guaranteed PhD funding is for 36 months and the contracts will be ±18 months at each hosting institute. The last, 4th year, is in accordance with the PhD program at Utrecht University.
The successful candidates will receive an attractive salary in accordance with the MSCA regulations for doctoral candidates. This includes a living allowance EUR 39,700- 52,000 annually, (this is a variable amount, based on an automatically calculated adjustment assuming the expected cost of living in the country of recruitment) and an additional mobility allowance (EUR 7200 per person per year). If applicable, a family allowance (Maximum of EUR 660 per person per month) will be paid. Please note that all compulsory national contributions (social security, pension, insurances, taxes etc.) to be borne by the employer and employee shall be deducted from the abovementioned amounts in line with MCSA Rules. These deductions vary between countries and institutes.
Candidates must not hold a doctoral degree. For the PhD positions the EU ‘Mobility rules’ apply. This means that candidate students cannot have resided for more than 12 months during the period of 3 years immediately before the start of the PhD, in the prospective first host country (Example: a candidate who has stayed in The Netherlands for more than 12 months in the last 3 years cannot be hired for the position where the first placement is at the university in The Netherlands).
Applicants must have an ability to understand and express themselves in both written and spoken English to a level that is sufficiently high for them to derive the full benefit from the network training.
Applicants must include their CV with detailed academic and professional records (e.g. work experience and publications). Pre-selection will be based on CV, experience, skills. Short-listed candidates will be encouraged to apply to the formal selection process (formal verification of eligibility criteria, titles and interview).
If you have questions about the positions, please contact dr. Anniek Bus (anniek.bus@anitom.be), or dr. Saskia Braber (s.braber@uu.nl).
Applications will be considered as off now until the position is filled.
If you are excited by the thought of this position and you wish to apply, please send your application (indicating the reference DC12) by email to:
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Utrecht University
- Country
- Netherlands
- City
- Utrecht
- Postal Code
- 3584 CS
- Street
- Heidelberglaan 8
- Geofield
- Number of offers available
- 1
- Company/Institute
- ANITOM
- Country
- Belgium
- City
- Sint-Truiden
- Postal Code
- 3800
- Street
- Straeten 2
- Geofield
Where to apply
- SSBB.HorizonEU@erasmusmc.nl