03/03/2022

Post-doctoral position in cell biophysics (project "Genome stability in mammalian oocytes and somatic cells”)

This job offer has expired


  • ORGANISATION/COMPANY
    Jagiellonian University, Faculty of Biochemistry, Biophysics and Biotechnology
  • RESEARCH FIELD
    Biological sciences
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    10/06/2022 23:00 - Europe/Brussels
  • LOCATION
    Poland › Kraków
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/07/2022

OFFER DESCRIPTION

A postdoctoral position is open for a highly motivated person with experience in cell biology and/or biophysics, to join our research group at Department of Cell Biophysics, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Kraków, Poland. The successful candidate will participate in a project which is focused on mechanisms of DNA damage induction and repair in mammalian oocytes and somatic cells. Cell biology and biophysical techniques will be used, including fluorescence confocal and super-resolution imaging, and various methods of detection of DNA damage and repair.

The overall goal of the proposal is to improve our understanding of the mechanisms behind a lower mutation rate of the female germline in comparison with somatic cells. The planned research involves direct measurements the numbers of endogenous single-strand DNA breaks (sSTRIDE technique, Nucl. Acids Res. 48(3), 2020, p. e14), measurements and imaging of localisation of critical SSB repair factors in oocytes and somatic cells, assessing the capacity of oocytes and zygotes to repair SSBs, and measurements of abundance of repair components and assessing their role in conferring resistance to DNA damage.

Jagiellonian University ranks among the best and the oldest (est. 1364) universities in Europe. Faculty of Biochemistry, Biophysics and Biotechnology offers state-of-the-art equipment and technological facilities, and ample collaboration opportunities with other research groups on the campus, in all disciplines of science. More information:

Jagiellonian University: https://en.uj.edu.pl/en_GB/start

Faculty of Biochemistry, Biophysics and Biotechnology: https://wbbib.uj.edu.pl/en_GB/start-en

Department of Cell Biophysics: https://helios.wbbib.uj.edu.pl/

 

Kraków is a vibrant city, one of the most visited tourist destinations in Europe, and a renowned centre of science and technology. For more information visit: https://www.lonelyplanet.com/poland/malopolska/krakow

More Information

Benefits

JU employees are covered by health insurance and pension scheme. Jagiellonian University offers an opportunity to benefit from additionally paid medical and sport services.

Selection process

Required Application Materials:

  1. Cover letter, including description of research interests
  2. Curriculum vitae
  3. Copies (pdf) of first author publications
  4. Names and contact information for at least two referees

The candidates who fulfil the criteria of the job announcement will be invited for an interview (Zoom, Skype).

APPOINTMENT

Appointment starting date: position open as of July 1st, 2022

Appointment term: three years

Salary: dependent on expertise and experience

Info about the lab: https://helios.wbbib.uj.edu.pl/en_GB/

Inquiries: jerzy.dobrucki@uj.edu.pl

Application deadline: 10th June 2022

Interested candidates should send the application documents by e-mail to: jerzy.dobrucki@uj.edu.pl

Additional comments

The project is funded by National Science Center, Poland, and Czech Science Foundation, Czech Republic.

Required Research Experiences

  • RESEARCH FIELD
    Biological sciences
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Biological sciences: PhD or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Good

Skills/Qualifications

Educational level: Applicants must have a Ph.D. or equivalent (biological sciences or physics)

Required languages: Good command of spoken and written English.

Specific Requirements

Hands-on experience with fluorescence confocal imaging, in vitro cell cultures, immunofluorescence, methods of detection of DNA damage and repair, western blots, plasmid multiplication. Experience with fluorescence super-resolution imaging is an advantage.

Work location(s)
1 position(s) available at
Cell Biophysics Department
Poland
małopolskie
Kraków
30-387
Gronostajowa 7

EURAXESS offer ID: 752760

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