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PhD position on ion mobility spectrometry of oligonucleotide and peptide-based therapeutics (MSCA Doctoral Network "MobiliTraIN")

22 Apr 2024

Job Information

Organisation/Company
University Geneva
Department
Pharmaceutical Sciences
Research Field
Chemistry » Analytical chemistry
Chemistry » Physical chemistry
Technology » Measurement technology
Pharmacological sciences » Other
Researcher Profile
First Stage Researcher (R1)
Country
Switzerland
Application Deadline
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
40
Is the job funded through the EU Research Framework Programme?
HE / MSCA
Marie Curie Grant Agreement Number
101119562
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

The University of Geneva offers a PhD position in the framework of the MSCA Doctoral Network MobiliTraIN (Ion Mobility Mass Spectrometry Training Network), hosted by the Gabelica group (Bioanalytical Mass Spectrometry, School of Pharmaceutical Sciences). The global project, conducted by 13 PhD candidates throughout Europe, aims to bring a new fundamental understanding of ion mobility-high resolution mass spectrometry (IM-HRMS), provide reference materials and guidelines for standardisation, develop state-of-the-art methods for the application of IM-HRMS in biopharmaceutical development, biological omics studies and non-target screening of contaminants, and lay the foundations for the adoption of IM-HRMS in industry by training 13 doctoral candidates.

PhD project description: The PhD project offered aims to develop ion mobility spectrometry of oligonucleotide and peptide-based therapeutics. The project will cover both fundamental aspects (role of ionization and ion activation conditions, effect of ion size) and applications relevant to the pharmaceutical industry.

Start date: upon mutual agreement, but no later than February 1st, 2025.

Secondments: This project is carried out in strong collaboration with the following groups, and visits to their laboratories are expected during the project. A willingness to travel and spend time abroad is therefore essential.

  • Host: Janssen, Belgium. Length: 3 months. Purpose: Get hands-on industry experience in oligonucleotide therapeutics characterization in a GXP environment and select molecular systems on which to focus more closely.
  • Host: Freie Universität Berlin, Germany. Length: 3 months. Purpose: Determine the structure(s) of folded oligonucleotides or peptidomimetics by combining cryo-IR spectroscopy and molecular modelling.

Requirements

Research Field
Chemistry » Analytical chemistry
Education Level
Master Degree or equivalent
Skills/Qualifications
  • Understand key concepts and relevant knowledge in molecular sciences and analytical sciences.
  • At least 6 months research experience gained during the masters studies or equivalent.
  • Ability to think critically about a scientific subject.
  • Ability to communicate fluently in English (oral, written) and synthesize thoughts.
  • Understand the value of collaborative work.
  • Curious to learn and open-minded.
Specific Requirements

Candidates must fulfil the MSCA Doctoral Networks Eligibility Criteria stated below.

Languages
ENGLISH
Level
Excellent
Internal Application form(s) needed
Application form MobilitraIN Gabelica.pdf
English
(194.77 KB - PDF)
Download

Additional Information

Benefits

Recruited researchers will be part of the MobililTraIN doctoral programme. MobiliTraIN offers:

  • A thorough scientific education in the frame of a doctoral training programme.
  • The possibility to participate in specific international training courses, workshops and conferences.
  • A strong involvement in a European research project with high international visibility.
  • The possibility to perform research visits to internationally renowned research labs in Europe.

The gross salary per year will be in the range of CHF 54'200. The exact net salary is dependent on local tax and social and health insurance regulations and will be confirmed upon appointment.

Eligibility criteria

Specific Eligibility Criteria of the Horizon Europe Marie Sklodowska-Curie programme apply, including the mobility rule and the PhD rule:

  • Mobility rule: Researchers must not have resided or carried out their main activity (e.g., work, study) in the country of the host organisation for more than 12 months in the 3 years immediately before the recruitment date (i.e., start of employment).
  • PhD rule: Applicants must be doctoral candidates, i.e., must not already be in possession of a doctoral degree at the date of recruitment.

Applicants of all nationalities are welcome to apply.

Selection process

We adopt the principles of the European Charter for Researchers and Code of Conduct for the Recruitment of Researchers, promoting open, merit-based and transparent recruitment and attractive working and employment conditions.

Applications submitted before the deadline will be screened based on the submitted files. The first decision (priority list, reserve list, or not retained) will be communicated to applicants by May 29, 2024. Candidates on the priority list will be interviewed by visioconference in presence of another member of the MobiliTraIN network. Final admission to the Doctoral School of Life Sciences of the University of Geneva (https://lifesciencesphd.unige.ch/) will require another formal interview with two professors from the program.

The reserve list of candidates may be kept until February 1st, 2025.

Ineligible or incomplete applications will not be considered.

Additional comments

To apply, please send 4 files by email to valerie.gabelica@unige.ch before May 23, 2024 (12:00 PM, Paris time):

  1. Application form provided above
  2. CV
  3. Personalized cover letter, outlining your motivation and adequacy of competences for the proposed research subject
  4. Name, affiliation and contact email of 2 references (people who are acquainted with your work or studies).
Website for additional job details

Work Location(s)

Number of offers available
1
Company/Institute
University of Geneva, Section of Pharmaceutical Sciences
Country
Switzerland
City
Geneva
Postal Code
1205
Street
9 Avenue de Champel
Geofield

Where to apply

E-mail
valerie.gabelica@unige.ch

Contact

City
Genève
Website
Street
Rue Michel-Servet 1
Postal Code
1211