Job Information
- Organisation/Company
- KU Leuven
- Research Field
- Neurosciences
- Researcher Profile
- First Stage Researcher (R1)
- Country
- Belgium
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Hours Per Week
- 38 hours/week
- Is the job funded through the EU Research Framework Programme?
- HE / MSCA
- Reference Number
- BAP-2024-159
- Marie Curie Grant Agreement Number
- 101119916
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
Traumatic brain injury can lead to devastating consequences for the patient and his family and is the number one cause of death and disability in young people. Medical management consists of the prevention, early detection and treatment of secondary insults that cause additional damage to the brain. Cerebrovascular autoregulation is an ingenious protective physiological mechanism that ensures sufficient cerebral blood flow in spite of varying blood pressure and other threats to homeostasis, that is however often impaired after traumatic brain injury. This impairment has been recognized as an extremely important threat to good outcome, and steering blood pressure based on its monitoring could mean a potential breakthrough in management. However, validated methods to monitor cerebrovascular autoregulation do not exist to date. In our lab, we have developed a piglet cranial window model through which the study of arteriolar diameter and flow changes in response to changes in blood pressure, PaCO2 and other external stimuli can be investigated. The piglets are instrumented with monitoring tools that are also being used in patients in the intensive care unit. The lab is also investing in the development of a severe traumatic brain injury piglet model, in order to enable the study of dynamic impairments of autoregulation capacity. The goal of the current project is to deepen our understanding of autoregulation mechanisms in physiological and pathophysiological conditions and to eventually build a validated patient autoregulation monitor.
Requirements
- Research Field
- Biological sciences
- Education Level
- Master Degree or equivalent
- Research Field
- Medical sciences
- Education Level
- Master Degree or equivalent
- Research Field
- Neurosciences
- Education Level
- Master Degree or equivalent
- Languages
- ENGLISH
- Level
- Excellent
- Research Field
- Biological sciences
- Years of Research Experience
- None
Additional Information
The candidate is offered:
- A full time PhD position in an international research team at KU Leuven. The KU Leuven is one of Europe's leading research universities and tops Reuters ranking of Europe's most innovative universities. L’NRG offers a dynamic and intellectually challenging environment, in close collaboration with experts from a wide variety of domains.
- A thorough scientific education and training in all relevant competences to advance the field of neuromonitoring, enabling the possibility to become a world-class researcher in this field.
- The possibility to actively participate in the network’s organizational structure and in international conferences and collaborations.
- A predetermined living allowance, and when appropriate a mobility allowance, family allowance, long-term leave allowance or special needs allowance according to EU standards corrected for the country of employment and integrally transferred to the researchers.
- The possibility to participate in international conferences and collaborations.
- The doctoral project start time is between June and October 2024.
The candidate should have a strong academic record and a Masters diploma in the fields of biomedical, medical, biological or neurosciences
Handson expertise in animal handling and experimentation is highly useful. Knowledge of data analysis and statistics is essential. Previous research experience is a plus, but not essential.
The candidate should be able to work independently, take initiative, adopt critical judgment and demonstrate ability to work in team. The project will include several network wide educational events in the SOPRANI consortium and a secondment, for which travel, communication and social skills are required.
Proficiency in written and spoken English is crucial.
The candidate can be of any nationality, but must not have resided or carried out his/her main activity Belgium for more than 12 months in the 3 years immediately prior to his/her recruitment.
The selected candidate is expected to write a doctoral thesis on her/his research after 4 years.
For more information please contact Prof. dr. Bart Depreitere, tel.: +3216348688, mail: bart.depreitere@kuleuven.be.Application is done by sending your CV and motivation letter to bart.depreitere@uzleuven.be.
You can apply for this job no later than 15/04/2024 via the online application tool
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- KU Leuven
- Country
- Belgium
- State/Province
- Vlaams Brabant
- City
- Leuven
- Postal Code
- 3000
- Street
- Leuven
- Geofield
Where to apply
- Website
Contact
- State/Province
- Leuven
- City
- Vlaams Brabant
- Street
- Leuven
- Postal Code
- 3000