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EURAXESS

Post-doctoral Position in Organic Chemistry: Synthesis of lipid metabolite-inspired amphiphiles for the study of pharmaceutical relevant membrane proteins

ABG  - Association Bernard Gregory
12 Mar 2024

Job Information

Organisation/Company
Avignon Université
Research Field
Chemistry
Researcher Profile
First Stage Researcher (R1)
Country
France
Application Deadline
Type of Contract
Temporary
Job Status
Full-time
Offer Starting Date
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

The Post-doctoral fellow will be in charge of the chemical ligation between lipid-inspired hydrophobic domains prepared in the team of Montpelllier and glycosyl donors as well as their purification and complete structural characterization (1D and 2D NMR, MS-UPLC…). He/she will study the colloidal properties of the final amphiphiles by means of surface tension and spectrofluorometry measurements as well as dynamic light scattering. He/She will be working side by side with a PhD fellow. The biochemical validation will be carried out on several types of proteins of fundamental and pharmaceutical interest in Paris-Saclay and in Lyon.

Requirements

Specific Requirements

To apply to this position, you should have

Extensive and proven experience in organic synthesis.
Extensive and proven experience in characterization/purification of amphiphilic organic compounds.
High-level competency in investigating self-aggregation properties of amphiphiles.
Experience in biophysics and biochemistry of membrane proteins is helpful, but not essential.
Creativity in experimental design and effective team-working skills.
Excellent communication skills in French and English

 

Additional Information

Work Location(s)

Number of offers available
1
Company/Institute
Avignon Université
Country
France
City
Avignon
Geofield

Contact

Website