Job Information
- Organisation/Company
- Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences
- Research Field
- Chemistry » Biochemistry
- Researcher Profile
- Recognised Researcher (R2)
- Country
- Poland
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Hours Per Week
- 40
- Offer Starting Date
- Is the job funded through the EU Research Framework Programme?
- Not funded by an EU programme
- Reference Number
- KSN 1/2024
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
- Employer: Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Krakow, Poland
- Research field: Chemistry > biochemistry
- Researcher profile: R2
- Deadline for applications: 08.04.2024, 3:00 pm GTM+1
- Place: Poland, Kraków
- Type of Contract: temporary
- Job Status: Full-time
- Working hours/week: 40
- Start of employment: 01.05.2024
- Key Words: proteins, enzymes, molecular biology, chromatographic protein purification, enzymatic kinetics, stopped-flow method
Jerzy Haber Institute of Catalysis and Surface Chemistry PAS invites applications for an Adjunct (post-doc) in the Theoretical and Experimental Biocatalysis group. The candidates who meet the conditions stated in the act “Ustawa o Polskiej Akademii Nauk” dated 30 April 2010 (Dz.U. 2018 poz. 1475 z póź. zm.), art 89. Ust. 3 for the position of Adjunct are encouraged to apply for the position.
The candidate will participate in research conducted in the Theoretical and Experimental Biocatalysis group on iron enzymes catalysing ring closing or cleavage reactions as part of the OPUS 23 research project. According to the short description of the project: "Very many natural products, a significant part of which are useful in medicine, contain in its structure one or more rings. As part of this project, we will undertake closely integrated research that will use protein crystallography, measurements of fast enzymatic kinetics, Mossbauer spectroscopy and computational methods (molecular dynamics simulations, QM/MM studies on reaction mechanisms, calculations of Mossbauer spectral properties, rational redesign of enzymes), in aim: to obtain crystal structures of enzymes and their complexes with substrates/mimetics or products, to elucidate the mechanisms of catalytic reactions, to unravel the structure and dynamic factors determining the activity, specificity and efficiency of enzymatic reactions, and to carry out rational redesign of enzymes.”
In particular, the Adjunct's responsibilities will include:
- protein production by overexpression in E. coli,;
- protein purification using affinity chromatography and molecular filtration;
- testing of enzymatic activity;
- enzymatic kinetics studies;
- studies of rapid enzymatic kinetics using stopped-flow and rapid freeze quench methods;
- preparing scientific publications.
Requirements
- Research Field
- Chemistry
- Education Level
- PhD or equivalent
- Research Field
- Biological sciences
- Education Level
- PhD or equivalent
- PhD degree in chemistry, biology or related fields;
- knowledge of molecular biology methods;
- knowledge of protein purification methods;
- knowledge of methods for determining enzymatic activity;
- knowledge of methods used to determine enzymatic kinetics;
- knowledge of the English language;
- ability to conduct independent scientific work;
- The candidate must meet the requirements specified in the NCN regulations governing the principles of employment for the postdoctoral position in the OPUS competition (23rd edition).
- An application.
- Completed and signed “Consent to the processing of personal data for the needs necessary to carry out the recruitment process” in accordance with the Act of 29 August 1997 on the protection of personal data (t.j. Dz. U. z 2016 r. poz. 922, z 2018 r. poz. 138, 723.) [FORM] and “Information obligations – recruitment of a perspective employee/collaborators” confirming acquainting with its content [FORM].
- A copy of scientific degree certificate.
- Full CV (including information on maternal leaves, voluntary work and periods of work in the industry).
- At least one opinion on the Candidate given by an independent researcher.
- List of scientific achievements (scientific papers, patent, patent applications, grants, etc.).
- The Candidate’s report on his/her scientific interests and research aims (an A4 page).
- Languages
- ENGLISH
- Level
- Good
- Research Field
- Chemistry » Biochemistry
- Years of Research Experience
- 4 - 10
Additional Information
Renumeration:
The gross salary 8200 PLN/month (roughly 1850 Euro/month) depending on the Candidate’s experience.
• Documented experience in conducting scientific research in the field of biochemistry, biological chemistry or related fields, confirmed by a list of publications in journals from the Journal Citation Reports list (0-10 points). Minimum number of points required: 3;
• Knowledge of protein purification techniques (0-5 points). Minimum number of points required: 2;
• Knowledge of enzymatic kinetics techniques (0-5 points). Minimum number of points required: 2.
Applications should be sent in electronic form to: sekretariat@ikifp.edu.pl with the subject title „Biocatalysis KSN 1/2024”
Deadline for applications: 08.04.2024 at 3:00 pmGTM+1. The competition will be settled by 22.04.2024. The candidates will be notified of the results.
The employment will be proceeded with accordance to the rules of Labour Code for 24 months.
The Institute has been adapted to the needs of the disabled. The Institute does not provide accommodation. The recruitment process is conducted according to OTM-R policy.
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Jerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences
- Country
- Poland
- City
- Krakow
- Postal Code
- 30-239
- Street
- Niezapominajek
- Geofield
Where to apply
- sekretariat@ikifp.edu.pl
Contact
- City
- Krakow
- Website
- Street
- Niezapominajek 8
- Postal Code
- 30-239
- jan.zawala@ikifp.edu.pl