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EURAXESS

Rif. 1421 - Extracellular vesicle and single cell metabolism mapping in Acute Myeloid Leukemia

Italian Ministry of Education, University and Research
7 Mar 2024

Job Information

Organisation/Company
ALMA MATER STUDIORUM - Università di Bologna
Department
DIMEC - DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Research Field
Medical sciences » Other
Researcher Profile
Recognised Researcher (R2)
Leading Researcher (R4)
First Stage Researcher (R1)
Established Researcher (R3)
Country
Italy
Application Deadline
Type of Contract
Temporary
Job Status
Other
Offer Starting Date
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

Alterations in cell metabolism and metabolic adaptation are crucial hallmarks for Acute Myeloid Leukemia (AML), an aggressive disease with a high relapse rate. Thus, new ways to detect metabolic modulation using blood would be valuable and highly informative for diagnosing and monitoring AML progression. Intriguingly, growing evidence has highlighted the key role of extracellular vesicles (EVs) as a liquid biopsy platform. However, the cargo of EVs and their role in the metabolic regulation of leukemic cells or immune cells are still elusive in AML. The main goal of this project is to study the metabolic profile of leukemic cells/immune cells and the phenotype and cargo of EVs in parallel from peripheral blood and bone marrow samples of AML patients at diagnosis and after therapy

Requirements

Research Field
Agricultural sciences » Other
Education Level
PhD or equivalent
Languages
ENGLISH
Level
Good
Research Field
Medical sciences
Years of Research Experience
1 - 4

Additional Information

Work Location(s)

Number of offers available
1
Company/Institute
ALMA MATER STUDIORUM - Università di Bologna
Country
Italy
City
Bologna

Where to apply

Website