Postdoctoral position in Immunology (TVL13/100%) “Metaflammation-induced reprogramming of liver regeneration”

The Institute of Molecular Medicine and Experimental Immunology (IMMEI) at the Medical Faculty Campus of Bonn University Clinic invites applications for a

Postdoctoral position in Immunology (TVL13/100%)

on “metaflammation-induced reprogramming of liver regeneration”. This project focuses on liver-resident macrophages (Kupffer Cells, KCs) - key players in liver regeneration. Depletion of KCs has shown to suppress liver regeneration and increase mortality. We aim to identify the cellular and molecular mechanisms induced by metaflammation, leading to the transcriptional reprogramming of hepatic macrophages and their precursors. We investigate how these changes alter KC reconstitution, resulting in functional dysregulation during liver regeneration after acute liver injury or surgical resection. For more information, see https://www.sfb1454-metaflammation.de/post/project-p10

IMMEI, located at the Medical Faculty Campus of Bonn University Clinic, provides an exceptional environment for cutting-edge research. Our state-of-the-art facilities offer a platform for collaboration and innovation. Led by Prof. Dr. Zeinab Abdullah, our project provides an opportunity to make significant contributions to the scientific community under her expert guidance.

The successful candidate is anticipated to demonstrate intellectual engagement and interactive dedication to the position by staying up-to-date about relevant literature and research publications. Additionally, they will be tasked with delivering presentations during lab meetings, as well as drafting the detailed methods, results, figure legends, and figures for grant proposals, progress reports, and manuscripts.

Required Qualifications:

• Ph.D. in Biology, Immunology, Molecular Biology, or related fields.
• Strong background in Immunology.
• Proficiency in small animal surgical techniques.
• Ability to work both independently and in a team environment.
• Excellent English communication skills.
• Published research in peer-reviewed journals within the life science field.

Desired Qualifications:

• Strong background in macrophage biology or liver immunology.
• Proficiency in flow cytometry, imaging, or proteomics.
• Strong background in Bioinformatics.
• Experience in proposal writing and project coordination.

What We Offer:

• Salary according to the German salary scale TV-L E13 100%.
• Contract for 2 years with the possibility of extension up to 3 years.
• Supplementary benefits in the public sector, including a pension plan according to VBL.
• Opportunity to contribute to cutting-edge research with real-world implications.
• Access to state-of-the-art facilities and resources.
• Opportunity to collaborate with a dynamic and interdisciplinary team.
• Extensive training opportunities

How to Apply:

Interested candidates should submit a cover letter, CV, reference letters, and contact information for two references by 18.03.2024. Please consolidate all required documents into a single .pdf file labelled “Metaflammation Postdoc application – [Your Name]”. Submit it via email to Dr. Sara Klose sara.klose@uni-bonn.de with the subject line “Metaflammation Postdoc application – [Your Name]”. The starting date is negotiable, with a focus on getting started as soon as possible.

Diversity and Equal Opportunity:

The University of Bonn is committed to diversity and equal opportunity irrespective of gender, ethnicity, age, nationality, religion, disability, etc. As such, applications will be assessed in accordance with the Landesgleichstellungsgesetz (State Equality Act).