Job Information
- Organisation/Company
- CNRS
- Department
- Institut Interdisciplinaire de Neurosciences
- Research Field
- NeurosciencesBiological sciences
- Researcher Profile
- First Stage Researcher (R1)
- Country
- France
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Hours Per Week
- 35
- Offer Starting Date
- Is the job funded through the EU Research Framework Programme?
- H2020 / ERC
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
The project will focus on engineering and structure determination of neuronal protein-receptor complexes that are important for neurotransmission.
The project is already in an advanced stage, which means that the candidate will be able to build quickly on a significant body of existing results
The work will involve protein production from mammalian cells, protein purification and protein chemistry, biophysical interaction analysis (SPR, BLI), engineering of protein-protein interactions, and structure determination using X-ray crystallography and cryo-EM.
Created on January 1, 2011, the Institut interdisciplinaire de neurosciences (IINS) is a joint research unit attached to the CNRS and the University of Bordeaux. With 170 staff in 14 teams, IINS combines multidisciplinary skills to study the molecular and cellular mechanisms involved in brain activity. The Institute develops innovative methods in imaging, chemistry, physiology and computer science. A component of Bordeaux Neurocampus, IINS is one of the major players in the neuroscience community in Aquitaine.
This is a full-time position. The project will be carried out under the supervision and mentorship of Dr. Jonathan Elegheert.
Requirements
- Research Field
- Neurosciences
- Education Level
- PhD or equivalent
- Research Field
- Biological sciences
- Education Level
- PhD or equivalent
- Languages
- FRENCH
- Level
- Basic
- Research Field
- Neurosciences
- Years of Research Experience
- None
- Research Field
- Biological sciences
- Years of Research Experience
- None
Additional Information
The candidate must hold a PhD degree and have less than seven years of post-doctoral experience at the start of the contract. The candidate should have a solid background in molecular biology, biochemistry and/or structural biology. Experience with (i) mammalian expression systems (HEK293 cell lines), (ii) biophysical analysis methods (surface plasmon resonance, isothermal titration calorimetry, microscale thermophoresis, bio-layer interferometry, etc.), and (iii) X-ray crystallography or cryo-EM, is preferred. The candidate should be highly motivated, a team player, and have a can-do problem-solving attitude.
- Website for additional job details
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Institut Interdisciplinaire de Neurosciences
- Country
- France
- City
- BORDEAUX
- Geofield
Where to apply
- Website
Contact
- City
- BORDEAUX
- Website