Job Information
- Organisation/Company
- Université Libre de Bruxelles
- Research Field
- Biological sciences » Biological engineeringBiological sciences » BiologyMedical sciences
- Researcher Profile
- Recognised Researcher (R2)Leading Researcher (R4)First Stage Researcher (R1)Established Researcher (R3)
- Country
- Belgium
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Offer Starting Date
- Is the job funded through the EU Research Framework Programme?
- Not funded by an EU programme
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
Summary of the project
While new therapeutic advances have greatly improved the prognosis of patients with high-risk or even metastatic melanoma, various resistance mechanisms have been identified, prompting researchers to find combinations to counter them. This project aims to develop a specific nanomedicine to be further combined with the first line adjuvant therapies for melanoma. The study aims to reach proof of targeting of the formulation with pharmacokinetic and toxicological profiles’ determination and provide preclinical efficacy data in vivo.
Résumé du projet
Bien que les nouvelles avancées thérapeutiques aient considérablement amélioré le pronostic des patients atteints de mélanome à haut risque ou même métastatique, divers mécanismes de résistance ont été identifiés, incitant les chercheurs à trouver des combinaisons pour les contrer. Ce projet vise à développer un nanomédicament spécifique qui serait associé aux thérapies adjuvantes de première ligne pour le mélanome. L'étude vise à prouver le ciblage de la formulation en déterminant ses profils pharmacocinétique et toxicologique et à fournir des données précliniques sur l'efficacité in vivo.
Funding category: Financement public/privé
PHD title: Doctorat en sciences biomédicales et pharmaceutiques
PHD Country: Belgique
Requirements
Background required: master in biology, biomedical sciences, pharmacy, biotechnology, bioengineering. People with PhD diploma ARE NOT eligible.
Skills (preferred; may be acquired during the training): cell culture, cell transfection, molecular biology, PCR, Western blot, Drug delivery
Domain of the research: experimental oncology, pharmaceutical sciences, molecular biology
Language: fluent French or English is required
Additional Information
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Université Libre de Bruxelles
- Country
- Belgium
- City
- Bruxelles
Where to apply
- Website