Postdoctoral Researcher Advanced Fluorescence Microscopy

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).

Please, check out our Recruitment Policy

The role

The position is expected to be filled by a PhD-level candidate with experience in bioimage analysis and advanced fluorescence microscopy. The candidate will focus on the application of live cell fluoresce microscopy to study single cell and multicellular dynamics and the analysis of spatio-temporal features regulating morphodynamics and pattern formation.

The candidate should be enthusiastic to work in a collaborative and interdisciplinary research environment. This work will be performed within the European Synergy Grant ‘Breakdance’ that involves 4 European research partners in Spain and France.

About the lab

The Ruprecht lab studies fundamental mechanisms regulating cellular morphodynamics, tissue plasticity and multicellular self-organization during development and disease conditions. The team employs a cross-disciplinary approach that combines quantitative fluorescence microscopy, biophysical methods, synthetic biology approaches and in vivo model systems. Our work has recently identified that nuclear mechanosensing controls cellular mechano-plasticity (Venturini et al. Science 2020) and has elucidated mechanisms of developmental robustness via cellular error correction in the early embryo (Hoijman et al. Nature 2020). Our ultimate goal is to develop a mechanistic understanding how tissue form and function is robustly built and maintained by dynamic processes at the single cell level and of alterations of cell states in disease and ageing.

The research group is part of the Quantitative Cell Biology Program and Systems and Synthetic Biology Program at the CRG.

Whom would we like to hire?

Professional experience

Must Have

• You have expertise in bioimage analysis and advanced fluorescence microscopy methods
• You have developed computational tools for image processing and analysis

Education and training

• You hold a PhD degree in physics, mathematics, informatics or a related field with relevant qualifications

Languages

• You are fluent in English, and you have excellent communication and writing skills

Competences

• You are a highly motivated person with analytical problem-solving skills
• You bring an excellent scientific track record
• You are enthusiastic to work in a collaborative and interdisciplinary research team

Technical skills

• You have worked with 2D, 3D and 4D live cell fluorescence microscopy data
• You have experience in handling multi-modal imaging data (widefield, confocal, light sheet microscopy)
• You have gained practical skills in AI-based image analysis methods
• You bring experience in different programming languages (Matlab, Phyton, Fiji, and similar)
• You are proficient in statistical data analysis
• You are knowledgeable in cell and developmental biology

The Offer – Working Conditions

• • Contract duration: Technical and scientific activities contract - estimated project duration one year with the possibility to extend
  • Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.
  • Target start date: as from January 2024

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

1. A motivation letter addressed to Dr Verena Ruprecht.
2. A complete CV including contact details.
3. Contact details of two referees.

All applications must be addressed to Dr. Verena Ruprecht and be submitted online on the CRG Career site - http://www.crg.eu/en/content/careers/job-opportunities

Selection Process

• Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based.

• Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.

• Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.

Deadline: Please submit your application by February 12^th, 2024.