PhD topic in Plant Molecular Biology Research Group

Research group homepage:

https://riha.ceitec.cz/

Topic title: RNA condensates in plant stress adaptation

Supervisor: Mgr. Karel Říha, Ph.D.

Annotation:

The topic of this proposal is to investigate the role of cytoplasmic RNA condensates (P-bodies
and stress granules) in plant adaptation to abiotic stress, including heat stress and salt stress. Pbodies and stress granules (SG) are known to play a crucial role in RNA storage, translation, and
decay, and their structure and behavior dynamically respond to both developmental and
environmental stimuli. However, we still have a limited understanding of how these
biomolecular condensates contribute to the regulation of plant growth and stress responses. In
this project, the candidate will utilize genetics, genomics, and cell biology approaches to explore
the regulation of SG and P-bodies by stress response kinases in model plants like Arabidopsis
thaliana, as well as in rice and barley.

Keywords: cytoplasmic RNA condensates, plant adaptation, abiotic stress

Recommended literature:
DOI: 10.1104/pp.17.01468
DOI: https://doi.org/10.1038/nrm.2017.7

Requirements on candidates:

Solid theoretical background in genetics, molecular biology and cell biology. Practical experience
in plant biology, bioinformatics or microscopy is a bonus, but not essential. Motivation and drive
are must.

APPLY: https://ls-phd.ceitec.cz/how-to-aplly/