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EURAXESS

CherISH_DC03 - Impact of internaural time delay on sound localisation

23 Nov 2023

Job Information

Organisation/Company
Eberhard Karls Universität Tübingen
Department
Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde
Research Field
Engineering » Biomedical engineering
Medical sciences » Medicine
Biological sciences » Biology
Neurosciences
Researcher Profile
First Stage Researcher (R1)
Country
Germany
Application Deadline
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
38,5
Offer Starting Date
Is the job funded through the EU Research Framework Programme?
H2020 / Marie Skłodowska-Curie Actions
Marie Curie Grant Agreement Number
101120054
Is the Job related to staff position within a Research Infrastructure?
No

Offer Description

The PhD student will be co-supervised by Professor Hubert Löwenheim (Medical Director of the ENT-Clinic in Tübingen) and Dr. Thore Schade-Mann (ENT-specialist).

For the localization of sounds, the auditory system uses, among other features, the time difference of the sound between the two ears (interaural time delay, ITD). For patients with disabling hearing loss, artificial hearing systems can partially restore audibility. While for lower grades of hearing loss conventional hearing aids (HAs) are used, cochlear implants (CI) are a therapeutic option for the treatment of profound hearing loss. During CI surgery, an electrode array is inserted into the cochlea which stimulates the auditory nerve electrically. In HA and CI, time differences between sound pickup by the microphones and the first signal processing in the auditory nerve vary considerably. Incompatibilities in the temporal dynamics of the binaural auditory signals in patients using a HA on one and a CI on the other ear result in an almost complete loss of directional hearing in these bimodally fitted patients.The project DC-03 of the European Training Network project aims to understand the impact of different hearing conditions on spatial hearing (SSD, HA-CI, CI-CI). As CIs bypass the external and middle ear, as well as the mechanotransduction in the inner ear, the signal reaches the central auditory pathway much quicker than in a normal hearing ear. Acoustic hearing aids (HA) introduce an additional delay, further increasing the ITD and affecting sound localization capabilities. The influence of biographical and clinical data as well as the underlying genetic background of hearing loss will be evaluated. So far, it has been shown only in a laboratory environment that the harmonization of the transit time for bimodally fitted patients results in improved sound localization capabilities. Real-world evidence for an improvement of spatial hearing is still missing.Subjects with different hearing conditions (SSD, HA-CI, CI-CI) will be examined with regard to their sound localization abilities. Individual ITD will be measured by comparing latency differences of the individual waves of the auditory brainstem potentials. The impact of the ITD will be recorded by questionaries and directional hearing tests. To check if the directional hearing deficits can by rescued by compensation for the abnormal ITD, an investigator-initiated clinical study will be conducted: The CI audio processor will be programmed to compensate for the established ITD. Sound localization tests and speech audiometry will be repeated shortly after the correction and after a week.

We are seeking an excellent highly motivated and intellectually curious PhD student to work on this project. A background in otolaryngology, audiology, neurophysiology and experience in experimental working, programming skills, knowledge of signal processing and data analyses and machine learning methods are prerequisites. It is expected that the candidate is eager to deal with complex challenges and is able to systematically develop solutions both independently and in a team. The doctoral candidate DC3 will interact with CI users and will utilize cutting-edge techniques: multivariate pattern analysis of electrophysiological data (multi-channel EEG). For a smooth interaction with patients very good knowledge of German language is essential in addition to good English proficiency. The PhD candidate will interact actively and closely with the two other local PhD candidates (DC1 and DC2) and within the whole doctoral network. The candidate will benefit from the exchange with other project partners and from secondments, by sharing individual experiences and knowledge.

Requirements

Research Field
Engineering » Biomedical engineering
Education Level
Master Degree or equivalent
Research Field
Psychological sciences » Cognitive science
Education Level
Master Degree or equivalent
Research Field
Neurosciences » Other
Education Level
Master Degree or equivalent
Skills/Qualifications

Excellent and strongly motivated candidates are sought exhibiting a general attitude suited to research, i.e. being intellectually curious, eager to explore and learn, capable of critical thinking, open to innovation, able to cleverly use their skills to address unknown problems, not scared about complexity. In particular, they should be open to the multidisciplinary approach needed to realize this project.

A solid scientific background will be required, if possible, in the neurophysiology of hearing. Adequate competences in neurophysiological experimenting, programming, signal analysis, statistics and machine learning. Familiarity with neuroscientific concepts and solid background in natural science is beneficial. Any further specific skills useful for researching in the field of rehabilitation medicine will be also highly valued.

The PhD candidate will work with patients with hearing impairments. It is important to be sensitive to their limitations and needs and to develop empathy towards them. To communicate with the patients, well very good German Language skills are needed.

The idea of the training network is to advance one's own project in cooperation with other scientists. It is therefore crucial that the PhD candidate can work efficiently both independently and in a team.

Since the MSCA positions are particularly intended to increase students’ mobility and facilitate international cooperation and mutual exchange of knowledge, a good teamwork attitude, with an open mind keen to interact positively with people from different cultures and backgrounds, will be also required.

Languages
ENGLISH
Level
Good
Languages
GERMAN
Level
Good

Additional Information

Benefits
  1. You will receive a 3-year full-time employment contract, enrolled in a PhD program. The salary is in accordance with the MSCA regulations for Doctoral Researchers and the exact (net) salary will be confirmed upon appointment and is dependent on local tax regulations and on the country correction factor applied by EU. The salary includes a living, mobility, and family allowance (if applicable). “Family” is understood to be people linked to the researcher by marriage (or by a relationship with a state equivalent to marriage recognized by the legislation of the country where this relationship was formalized) or dependent children who are supported by the researcher. The family relationship and/or dependence of children with the researcher must be accredited by official document. (for more information see here https://marie-sklodowska-curie-actions.ec.europa.eu/actions/doctoral-ne…)
  2. We offer modern, state-of the art laboratories, facilities, and equipment, as well as participation in training activities at the Tübingen University, the local Graduate Training Center of Neuroscience (Doctoral program), and within the international and intersectorial CherISH network (CherISH website – coming soon).
  3. You will travel for 2 planned secondments, annual meetings, workshops and national/international conferences.
  4. Work-life balance in a middle-sized university city offering options for outdoor, sport & cultural activities
Eligibility criteria

We welcome applications from Doctoral Researcher candidates fulfilling the following criteria:

  1. Not having already received a PhD or equivalent degree by any institution; researchers who have successfully defended their doctoral thesis but who have not yet formally been awarded the doctoral degree will not be considered eligible.
  2. They can be of any nationality but must not have resided or carried out their main activity (work, studies, etc.) in the country of the recruiting organization for more than 12 months in the 36 months immediately before their recruitment date. Time spent as part of a procedure for obtaining refugee status under the Geneva Convention (1951 Refugee Convention and the 1967 Protocol), compulsory national service, and/or short stays such as holidays are not considered.
  3. They must also be eligible to work in Germany according to regulations (e.g. visa requirements), and also to travel/work in other European countries for collaborations/secondments and trainings;
  4. They must meet the entry requirements for PhD enrolment in the University of Tübingen.

They must hold a 2nd Level Master Degree in life sciences (neuroscience, neurobiology, biomedical engineering or closely related fields).

  1. Being proficient in English and German (a minimum of B2 level or equivalent is desirable) and agreeing to use the English language both for work and for any other official matter, including the selection process.
  1. Must be available to enroll full-time in the PhD program at UT early Sept 2024.
  2. Are aware of and adhere to the principles set out in the Commission Recommendation on the European Charter for Researchers.
  3. Agreeing to undertake the PhD training program associated to this position, in case they are selected;
  4. Agreeing to move to Tübingen area (Germany) for the entire duration of the contract, in case they are selected.
  5. Agreeing to travel for the 2 secondments (6 weeks each) planned at project partners (other countries).
Selection process

Applications must be sent by email to aurore.brugeaud@med.uni-tuebingen.de
In the Subject of the email, please write “CherISH- PhD candidate Application – Project DC3”

Applications must be in English. Each applicant can apply to a maximum of three individual research projects within the Doctoral network CherISH.

The application consists of (PDF):
- CV (including publications if any);
- 1-page motivation letter;
- Recommendation letters (min 2 ; max 3)

Be aware that official transcripts of any degree achieved, preferably including average or final marks and explanation of the related assessment scale or criterion (mandatory for the main graduate degree, optional for the others) will be required for the enrolment in the University/PhD program; All documents must be in German or English. Any translations must be certified.

Additional comments

Recruitment Process

1. Evaluation of the applications based on eligibility criteria

2. Assessment on paper of qualifications and activities by the Selection committee

3. Online-interview for the selected candidates

The selection of the Doctoral Researcher candidates will be carried out in compliance with the general rules for HE-MSCA projects and will be based just on individual merit.

The selection process will be entirely carried out in English.
Be aware that you application could be transferred to another Partner of the Consortium

CherISH.
A Selection Committee consisting of 3 members and 1 observer was appointed by the CherISH Consortium for the evaluation of the application of the candidates for Subproject 3. Applications which do not meet the minimal prerequisites listed in the Specific Requirements section, or which are not submitted according to the procedure specified in the Offer Description section, or which are received after the submission deadline has expired, will be rejected.

The Selection Committee will send proper acknowledgement for each incoming submission. Whenever necessary, it will be also entitled to ask the candidates to provide any further document, information or clarification deemed useful to properly complete the assessment process.

Personal data will be stored for the purpose of carrying out the application procedure. Application costs cannot be reimbursed.

Questions and Answers:

For more information about the project (not the recruitment process), please write an email to christoph.braun@uni-tuebingen.de 

Are you interested? Please hand in your application to aurore.brugeaud@med.uni-tuebingen.de

Work Location(s)

Number of offers available
1
Company/Institute
HNO-Klinik
Country
Germany
City
Tübingen
Postal Code
72076
Street
Elfriede-Aulhorn-Straße 5
Geofield

Where to apply

E-mail
aurore.brugeaud@med.uni-tuebingen.de

Contact

City
Tübingen
Website
Street
Elfriede-Aulhorn-Straße 5
Postal Code
72076
E-Mail
aurore.brugeaud@med.uni-tuebingen.de