Job Information
- Organisation/Company
- Instituto de Tecnologia Química e Biológica António Xavier ITQB NOVA
- Research Field
- Chemistry » BiochemistryPhysics » Biophysics
- Researcher Profile
- First Stage Researcher (R1)
- Country
- Portugal
- Application Deadline
- Type of Contract
- To be defined
- Job Status
- Full-time
- Hours Per Week
- 35
- Offer Starting Date
- Is the job funded through the EU Research Framework Programme?
- Not funded by an EU programme
- Reference Number
- 048/BI/2023
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
Instituto de Tecnologia Química e Biológica António Xavier
Application for a Master Fellowship
within the project PTDC/BIA-BFS/0391/2021
Applications are invited for a Master Fellowship in the scope of the project entitled “HUBs – The architecture of a pathogen-driven signaling Hub” with the Ref. PTDC/BIA-BFS/0391/2021, funded by FCT- Fundação para a Ciência e a Tecnologia I.P./MCTES.
Main Scientific Areas & Sub Research Fields: Chemistry – Biochemistry; Physics – Biophysics
Academic degree: We seek candidates with a Master’s degree in Chemistry/Biochemistry/Biophysics to participate in a multidisciplinary research program focused on signaling and host-pathogen interactions.
Other requisites:
• Research interests should lie at the interface between chemistry and biology;
• Eager to dissect molecular mechanisms at the host-pathogen interface;
• Highly motivated and passionate junior researcher;
• Prior experience with ITC, SAXS and NMR will be a plus;
• Good organizational and teamwork skills;
• Fluency in spoken and written English;
• Bachelor’s degree classification of 14 (or higher) and a master’s degree classification of 17 (or higher);
• Being enrolled in a PhD or a non-academic degree course, by the time of the signature of the contract , in accordance with number the Article 6th of Regulations for Research Fellowships from Fundação para a Ciência e a Tecnologia, I.P., law in force.
Working Plan: Pathogenic microbes that invade a human host have developed sophisticated strategies to rewire host-signaling pathways and down-regulate host immune responses. Bacterial pathogens use a plethora of secreted effectors and cell-associated proteins to achieve this goal during infection.
The HUBs project aims to illuminate how pathogen-encoded proteins hijack host cells from an integrative structural biophysics perspective. Within this framework, we offer an opportunity to dissect the complex structural dynamic facets of a prominent effector produced by life-threatening human pathogens. To this end, the selected candidate will be engaged in protein expression and purification and experimental and computational approaches, receiving training small-angle scattering, and NMR hybrid applications.
Applicable Law and Regulations: Status of Scientific Research Fellow, approved by Law number 40/2004, of August 18th, changed and republished by Ordinance 202/2012 of August 27th and changed by Ordinance 233/2012 of October 29th and by Law 12/2013 of January 29th and by Ordinance 89/2013 of July 9th and by the Ordinance 123/2019 of August 28th; Regulations for Research Fellowships from Fundação para a Ciência e a Tecnologia, I.P., in force (https://www.fct.pt/apoios/bolsas/docs/RegulamentoBolsasFCT2019.pdf).
Working Place: The work will be done in the Dynamic Structural Biology Lab (Supervisor: Tiago N Cordeiro).
Duration of the fellowship: The fellowship will have the duration of 6 months, eventually renewable, expected to start in June 2023, on a full-time basis, according to according to Fellowship Regulations of Fundação para a Ciência e Tecnologia, I.P.
Stipend amount: EUR 1199,64 €, according to the table of values of grants awarded directly by the FCT, I.P. in the Country (https://www.fct.pt/wp-content/uploads/2023/02/Tabela-de-Valores-SMM_202…) and payment will be made, monthly, through bank transfer.
Selection procedure: Applications will be evaluated according to the analysis of the documents presented - Curriculum (60%), motivation letter (10%), references (10%), and interview, if considered necessary by the jury, of the selected candidates (20%). The final results will be presented on a scale from 0 to 100.
Jury composition: Doctor Tiago N. Cordeiro (President); Doctor Pedro Domingos (member); Doctor Zach Hensel (member); Doctor Tiago Gomes (substitute member).
Application documents:
• Full Curriculum Vitae;
• A motivation letter detailing previous work experiences related to the project;
• Degree certificate*;
• Contacts information or letter of recommendation of two referees.
All documents should preferably be sent by email in a single pdf file.
*If the degree has been conferred by a non-Portuguese higher education institution, the selected candidate must obtain the certificate of degree recognition issued by the Portuguese Directorate General for Higher Education or by a Portuguese Public Higher Education Institution until the signature of the contract. Regarding this issue, please consult the Portuguese Directorate General for Higher Education website: https://www.dges.gov.pt/en.
Notification of candidates: All the candidates will be informed of the final result by e-mail.
Deadlines and procedures for complaints and appeals: If the result is not favorable, the candidates have a period of 10 working days, after the disclosure of the results, to comment, if desired, in a prior hearing of interested parties, in the terms provided for in the Code of Administrative Procedure.
Application period: From 9 to 22 of May 2023
Applications should be sent to:
Doctor Tiago N Cordeiro
tiago.cordeiro@itqb.unl.pt
Ref. 048/BI/2023
OEIRAS
Requirements
- Research Field
- Chemistry » Biochemistry
- Education Level
- Master Degree or equivalent
Additional Information
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- ITQB NOVA
- Country
- Portugal
- State/Province
- Oeiras
- City
- Oeiras
- Postal Code
- 2780-156
- Street
- Av da Republica, INIAV
Where to apply
- tiago.cordeiro@itqb.unl.pt
Contact
- State/Province
- Lisboa
- City
- Oeiras
- Website
- Street
- Av. da República, E.A.N
- Postal Code
- 2780-156
- itqb.projects@itqb.unl.pt