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EURAXESS
NEWS11 Jun 2021NewsFundingFrance

PhD grants "Addiction transfer between alcohol and food in bariatric surgery and liver transplantation: prevalence and risk factors" (SSBCV)

university_de_tours

Description

DEADLINE: 15th June 2021

 

  • Keywords

 

addictive disorders , psychiatric disorders , food addiction , liver transplantation , addiction transfer addiction switch, ADHD

 

  • Profile and skills required

 

Do a regular monitoring of the scientific literature in line with the

objectives of the scientific project, including a critical appraisal of

these articles; regularly update the methodological aspects related to

the project.

 

- Write a literature review summarizing these different articles and

update this literature review with the new published/accepted papers.

 

- Identify the current gaps in knowledge as well as the opportunities

for scientific advances and new directions for research, identify and

address the keys issues and the controversies related to the scientific

topic.

 

- Analyze and discuss the project results in line with the primary

and the secondary objectives, and choose which results should be

integrated in a publication in a scientific Journal.

 

- Present the key results of the study during oral communications and

invited talks, by using the adequate ways to disseminate the results.

 

- Publish the key results as a first author in at least one JCR-referenced scientific Journal.

 

- Accept external criticism and different points of view; being able

to question personal points of view/scientific ideas and renew the way

of thinking using external advices/points of view.

 

Level of French required: Proficient/Current: You can use the language with ease and fluency in arguing complex issues.

 

Level of English required: Upper Intermediate: You can use the language effectively and express yourself accurately.

 

  • Project description

 

Alcohol use disorders and food addiction/compulsive eating behavior

are two prevalent disorders that share some vulnerability risk factors

(i.e., higher prevalence for psychiatric disorders, especially

attention-deficit/hyperactivity disorder, post-traumatic stress

disorder, and other affective disorders; higher impulsivity; low

interoceptive awareness). When one addictive disorder has to remit due

to a forced-withdrawal (e.g. when there is limited availability of the

substance or the behavior) and when there is the concomitant maintenance

of its risk factors, some authors hypothesized the possibility of an

addiction transfer/addiction switch, i.e., the risk for a second

addictive disorder after the remission of the first one.

 

Addiction transfer from alcohol to food or from food to alcohol have

been hypothesized to occur in vulnerable individuals, but we lack an

understanding of its prevalence and of its risk factors. The study of

addiction transfer between alcohol and food is easier in populations who

report both a high prevalence for one of these two addictive disorders,

and who have a limited availability to either alcohol or food due to a

forced abstinence. Bariatric surgery patients, who report a high

preoperative prevalence for food addiction/binge eating disorder, and

liver transplantation patients, who report a high preoperative

prevalence for alcohol use disorders, are two populations well-suited

for the study of addiction transfer between food and alcohol.

 

This study aimed to assess the prevalence of addiction transfer

between alcohol and food as well as its risk factors in these two

at-risk populations: (1) addiction transfer from food to alcohol in

patients undergoing obesity surgery and specification of its risk

factors; (2) addiction transfer from alcohol to food in patients

transplanted for an alcohol-related cirrhosis.

 

  • References

 

American Psychiatric Association. (2013). Diagnostic and statistical

manual of mental disorders (5th ed.). Washington, DC: American

Psychiatric Publishing. American Psychiatric Publishing, Inc.

 

Blaszczynski, A., & Nower, L. (2002). A pathways model of problem and pathological gambling. Addiction, 97(5), 487–499.

 

Bogusz, K., Kopera, M., Jakubczyk, A., Trucco, E. M., Kucharska, K.,

Walenda, A., & Wojnar, M. (n.d.). Prevalence of alcohol use disorder

among individuals who binge eat: A systematic review and meta-analysis.

Addiction, n/a(n/a). https://doi.org/10.1111/add.15155

 

Brunault, P., Salamé, E., Jaafari, N., Courtois, R., Réveillère, C.,

Silvain, C., Benyamina, A., Blecha, L., Belin, D., & Ballon, N.

(2015). Why do liver transplant patients so often become obese? The

addiction transfer hypothesis. Medical Hypotheses, 85(1), 68–75. https://doi.org/10.1016/j.mehy.2015.03.026

 

Burra, P., Senzolo, M., Adam, R., Delvart, V., Karam, V., Germani,

G., & Neuberger, J. (2010). Liver Transplantation for Alcoholic

Liver Disease in Europe: A Study from the ELTR (European Liver

Transplant Registry). American Journal of Transplantation, 10(1),

138–148. https://doi.org/10.1111/j.1600-6143.2009.02869.x

 

Ivezaj, V., Wiedemann, A. A., & Grilo, C. M. (2017). Food

addiction and bariatric surgery: A systematic review of the literature.

Obesity Reviews, 18(12), 1386–1397. https://doi.org/10.1111/obr.12600

 

Ivezaj, Valentina, Saules, K. K., & Wiedemann, A. A. (2012). “I

didn’t see this coming.”: Why are postbariatric patients in substance

abuse treatment? Patients’ perceptions of etiology and future

recommendations. Obesity Surgery, 22(8), 1308–1314. https://doi.org/10.1007/s11695-012-0668-2

 

King, W. C., Chen, J.-Y., Mitchell, J. E., Kalarchian, M. A.,

Steffen, K. J., Engel, S. G., Courcoulas, A. P., Pories, W. J., &

Yanovski, S. Z. (2012). Prevalence of alcohol use disorders before and

after bariatric surgery. JAMA, 307(23), 2516–2525. https://doi.org/10.1001/jama.2012.6147

 

Noel, X., Brevers, D., & Bechara, A. (2013). A neurocognitive

approach to understanding the neurobiology of addiction. Current Opinion

in Neurobiology, 23(4), 632–638. https://doi.org/10.1016/j.conb.2013.01.018

 

Steffen, K. J., Engel, S. G., Wonderlich, J. A., Pollert, G. A.,

& Sondag, C. (2015). Alcohol and Other Addictive Disorders Following

Bariatric Surgery: Prevalence, Risk Factors and Possible Etiologies.

European Eating Disorders Review: The Journal of the Eating Disorders

Association, 23(6), 442–450. https://doi.org/10.1002/erv.2399

 

To apply, click here