09/03/2018
Marie Skłodowska-Curie Actions

Post-doctoral position at University of Granada: Apply for an Athenea3i-2018 Research Fellowship at the Department of Atomic, Molecular and Nuclear Physics

This hosting has expired


  • OFFER DEADLINE
    01/09/2018 11:30 - Europe/Brussels
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions COFUND
  • LOCATION
    Spain, Granada
  • ORGANISATION/COMPANY
    International Research Projects Office
  • DEPARTMENT
    Promotion and Advisory Unit
  • LABORATORY
    NA

Professor Blanca Biel, from the Department of Atomic, Molecular and Nuclear Physics at the University of Granada, welcomes postdoctoral candidates interested in applying for an Athenea3i Research Fellowship in 2018 at this University. The information about the Fellowship conditions, how to apply, Eligibility Criteria, Selection Process, Evaluation Process, etc. is available in https://athenea3i.ugr.es/. Please note that applicants must comply with the Eligibility Criteria (https://athenea3i.ugr.es/?page_id=23).  

Brief description of the institution:

The University of Granada (UGR), founded in 1531, is one of the largest and most important universities in Spain. It serves more than 60000 students per year, including many foreign students, as UGR is the leader host institution in the Erasmus program. UGR, featuring 3650 professors and more than 2000 auxiliary personnel, offers a total of 75 degrees through its 112 departments and 28 centers.

UGR is also a leading institution in research, located in the top 5/10 of Spanish universities by a variety of ranking criteria, such as national R&D projects, fellowships awarded, publications, or international funding. UGR is one of the few Spanish Universities listed in the Shanghai Top 500 ranking (http://www.arwu.org/), and it is also well recognized for its web presence (http://www.4icu.org/top200/).

Internationally, we bet decidedly by our participation in the calls of H2020, both at partner and coordination. For the duration of the Seventh Framework Programme, the UGR has obtained a total of 66 projects, with total funding of 17.97 million euros, and for H2020, until 2015, more than 25 projects with total funding of more than 6 million euros. Our more than 3,000 researchers are grouped into 365 research groups covering all scientific fields and disciplines.

Brief description of the Centre/Research Group

The Department of Atomic, Molecular and Nuclear Physics (FAMN) at the University of Granada is a competitive lab whose members actively undertake research in high-impact areas such as quantum information, nuclear physics, nuclear medicine, and condensed matter at the atomic scale. The candidate will benefit from a multidisciplinary environment with frequent visits from researchers of other national and international institutions. Computational resources such as access to supercomputer facilities will be provided by the Universidad de Granada and the Spanish Supercomputing Network. Besides typical research and teaching activities, the FAMN is also very active in outreach and gender-awareness activities.

The project supervisor has active collaborations with both theoretical (Universidad Autónoma de Madrid, Spain; Nanosurf Lab-Institute of Physics of the CAS, Czech Republic) and experimental (Freie Universität Berlin, Germany; Zagreb Institute of Physics, Croatia) groups, of which the candidate will be able to benefit during his/her postdoctoral stay.

Project description

Peptide nucleic acid (PNA) is a synthetic molecule with multiple applications in both molecular diagnosis and treatment. It is much more selective than DNA or RNA in the detection of mutations, and can even detect mismatches of a single base. This ability, as well as the possibility of being able to be synthesized in the laboratory, makes it especially useful for its application in biosensors for the early detection of numerous diseases. However, the actual mechanism behind its selectivity or its intolerance of pairing errors when interacting with nucleic acids is not yet fully understood.

In this project we intend to advance the knowledge of this type of interactions based on recent experimental results. We will carry out a systematic analysis of the free energies of several APN-RNA, RNA-RNA and APN-APN compounds to elucidate on the factors that influence their couplings. As a first step we will use empirical methods based on force fields, to later refine the calculations using QM/MM methods.

Depending on the candidate’s interest and skills, the study of the electronic transport properties of the aforementioned systems by means of Non Equilibrium Green’s Functions methods, either developed by the candidate or using those already implemented in the available codes, will be also addressed.

Experience with one or more Molecular Mechanics (MM) or QM (Quantum Mechanics)/MM tools is required (AMBER, etc.)

This project is framed within a nationally funded project with a research group at the Universidad Autónoma de Madrid, who has recently developed the efficient QM/MM tool Fireball/Amber.

Research Area

  • Life Sciences (LIFE)
  • Physics and Mathematics (PHY-MAT)

For a correct evaluation of your candidature, please send the documents below to Professor Blanca Biel (biel@ugr.es@ugr.es):

  • CV
  • Letter of recommendation (optional)

Disclaimer:

The responsibility for the hosting offers published on this website, including the hosting description, lies entirely with the publishing institutions. The application is handled uniquely by the employer, who is also fully responsible for the recruitment and selection processes.