11/06/2018
Marie Skłodowska-Curie Actions

Nanoparticles for brain tumours and neurodegenerative diseases


  • OFFER DEADLINE
    30/06/2018 15:30 - Europe/Brussels
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • LOCATION
    Spain, Bellaterra
  • ORGANISATION/COMPANY
    Institut Català de Nanociència i Nanotecnologia

Brief description of the institution:

ICN2 is a renowned research centre. Its research lines focus on the newly discovered physical and chemical properties that arise from the behaviour of matter at the nanoscale.

The Institute promotes collaboration among scientists from diverse backgrounds (physics, chemistry, biology, and engineering) to develop basic and applied research, while seeking out new ways to interact with local and global industry.

It also offers researchers training in nanotechnology, develops numerous activities to promote and enable the uptake of nanotechnology by industry, and promotes networking among scientists, engineers, technicians, business people, society, and policy makers.

ICN2 was accredited in 2014 as a Severo Ochoa Centre of Excellence and is a founding member of the Barcelona Institute of Science and Technology (BIST). The aim of the Severo Ochoa Program, sponsored by the Spanish Ministry of Economy, Industry and Competitiveness, are to identify and support those Spanish research centres that demonstrate scientific leadership and impact at global level.

Brief description of the Centre/Research Group:

Molecular materials are uniquely placed to spur a revolution in the next decades, thanks to their ability to accommodate a wide span of functionalities, and the possibility to fine-tune them to suit a variety of technological purposes. However, while these materials already show optimal behaviour either in solution, as single crystals or as microcrystalline powders, their integration into functional devices still poses a scientific challenge, since once incorporated into solid matrices or hybrid devices, they often lose (at least partially) their inherent properties and/or their response efficiency.

Our objective at the Nanostructured Functional Materials research group (NANOSFUN) is to develop new strategies for obtaining molecular (bio)nanostructures with adapted properties and smart responses to external stimuli, which can be incorporated into solid matrices, surfaces or as stable colloidal suspensions, while retaining their initial properties and performance. For this, a wide range of molecular and biological building blocks are used, using Nature a strong source of inspiration. We work with the idea that ultimate control on every length scale and interface is required to reach the intrinsic limits and functions of these (supra)molecular materials, with their future introduction in our everyday life in sight.

Project description:

The objective of this project is to develop frontier research at the cross border between Neuroscience and Nanotechnology. More precisely, we aim to understand the role of catecholamine-based (and their intermediates) nanostructures created within the Central Nervous System (CNS) and the role they play in Neurodegenerative diseases via metal induced aggregation, ROS effect of radical polymerization.

More in detail, the work would be devoted to the treatment of some of the previously studied alterations with nanocarriers, mostly based on metal-organic and/or mesoporous silica nanoparticles. Work will include the design and fabrication of theranostics nanoplatforms for the controlled released of drugs together with tissue imaging.

Applications:

All applications must be sent to Dani Ruiz (dani.ruiz@icn2.cat) and include the following:

  • A full CV including contact details.
  • Motivation letter.
  • 2 recommendation letters.

 

Deadline for applications: 30th June 2018