20/04/2017
Marie Skłodowska-Curie Actions

Marie Skłodowska-Curie Individual Fellowship (IF) - Postdoc Position: metabolic fingerprinting of changes produced by exercise in people with mild cognitive impairment associated to aging.

This hosting has expired


  • OFFER DEADLINE
    31/07/2017 18:30 - Europe/Athens
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • LOCATION
    Spain, Madrid
  • ORGANISATION/COMPANY
    CEU Universities
  • DEPARTMENT
    Pharmacy Faculty

Universidad San Pablo CEU (CEU) is a young university founded in Madrid in 1993. CEU is committed to academic and professional excellence, aiming for the best quality in education, research and internationalization. CEU is a specialized University and structures its studies on three main fields of knowledge: “Social sciences and humanities”, “Health and life sciences” and “Architecture and Engineering”.

CEU facilities include 8 Research Centers, 43 Research Groups and 11 Core Research Facilities which sum an area of 3,400 m2 devoted to research. Over the past 3 years, University:

  • Has been granted 35 competitive research projects.

  • Achieves collaborations with Industry meaning 65% of R&D funding.

  • Obtained almost € 1M from European Commission 7th Framework Programme and is participating in three H2020 projects, including a MSCA-IF grant.

 

CEU is looking for a highly motivated candidate to apply for MSCA-IF-2017 calls, to join the selected applicant to participate in a currently on-going research project to study the effect of exercise in neurological disorders associated to aging.

Together with the selected candidate a proposal will be written and submitted. The involvement of the selected candidate in the proposal writing process will provide ample opportunity to tailor the proposal to her / his research interests. A successful application will result in an appointment under approved conditions.

The Center for Metabolomics and Bioanalysis (CEMBIO) is located at Pharmacy Faculty. www.metabolomica.uspceu.es.

CEMBIO team has more than 10 years’ research experience in metabolomics with mass spectrometry coupled to different separation techniques: Improving the analytical workflow, data mining strategies and collaborating with groups in different fields of application.

Coral Barbas, Head of CEMBIO, is Full Professor in Analytical Chemistry since 2007, and Marie Curie Researcher at King´s College London in 2005/2006, Prof. Barbas is visiting professor of Imperial College London, collaborating with Prof Jeremy Nicholson´s group, and at Medical University of Bialystok in Poland, collaborating with the doctorate program in “OMICS” technologies. Part of 12 national and 5 international R&D projects funded in public calls (12 as PI), and responsible of 12 cooperation contracts with different industries.

She has published more than 190 original papers in journals indexed in JCR, most of them in Q1. She has published 6 book chapters and she has participated as invited speaker in more than 60 international conferences. She has supervised 16 PhD thesis that obtained the highest mark.

CEMBIO team gathers 20 people from than 7 nationalities, including Professors, post-docs, PhDs, graduates, trainees and technical staff. Their areas of knowledge are: Analytical Chemistry; Mass Spectrometry; Biochemistry; Pharmacy; Statistics.

Main Equipment: LC-MS (QTOF); LC-MS(QqQ); LC-MS (Ion trap); GC-MS (Ion trap); GC-MS (Quadrupole); CE-MS (TOF); GC-QTOF-MS; Platforms for data treatment.

CEMBIO offers a unique opportunity to join an on-going research project to study the effect of exercise in neurological disorders associated to aging. Our specific interests are focused on the metabolic fingerprinting of changes produced by exercise, in people with mild cognitive impairment associated to aging.

There are cumulative experiences that physical conditioning has positive effects, not only on normal aging, but also on age-related neurodegenerative disease. Studies examining the beneficial effect of aerobic exercise on memory-impaired older adults are limited and primarily rely on retrospective measures of physical activity, unstructured (eg, home-based) programs, or general measures of cognitive function. This project offers access to samples coming from an intervention study.

Metabolomics provides deeper insights in the pathogenesis and discovery of biomarker patterns of diseases by obtaining a unique metabolite pattern, or “fingerprint” specific for each sample that provides information of compounds with a potential diagnostic or predictive power.

The prime aim of the project is to improve knowledge, disease understanding and to define new molecular pathophysiological mechanisms, related to the effect of exercise in brain activity.

Researcher will be working with new generation state-of-the-art equipment. Metabolomics data will be incorporated with the clinical characteristics of studied population for comprehensive univariate and multivariate statistical analysis, followed by extensive biochemical interpretation and final data interpretation.

The applicant will have the opportunity to work in an international and multidisciplinary group and publish results in peer-reviewed high indexes scientific journals.

At the deadline for the submission of proposals (14/09/2017), researchers (*):

  • Shall be in possession of a doctoral degree or have at least four years of full-time equivalent research experience.

  • Must not have resided or carried out their main activities in Spain for more than 12 months in the 3 years immediately prior to the abovementioned deadline.

An expression of interest shall be sent before 15th of July 2017. Your file should contain the following elements:

• A short CV: Only CVs with considerable scientific achievements will be considered. Candidates should have an excellent track record of research; they should demonstrate the ability to grow into scientific/technological leadership roles.

• A two-page research proposal.

• A short statement explaining why CEU would be the best host institution for your research.

• Two letters of reference.

Disclaimer:

The responsibility for the hosting offers published on this website, including the hosting description, lies entirely with the publishing institutions. The application is handled uniquely by the employer, who is also fully responsible for the recruitment and selection processes.