Marie Skłodowska-Curie European Fellowships - Expression of Interest

Expression of Interest - William Harvey Research Institute

The William Harvey Research Institute at Queen Mary University of London is one of the largest European multidisciplinary pharmacological institutes. It conducts basic, translational and clinical research in cardiovascular medicine, endocrinology and inflammation sciences.

We are inviting expressions of interest from exceptional candidates who wish to apply for a postdoctoral European Fellowship in one of the following topics:

Centre for Endocrinology

• Role of cancer stem cell in CNS tumours

• Genetic changes in pituitary adenomas

• Regulation of adrenal function and metabolism

• Exploring skin development, regeneration and diseases

• Cell stress and molecular chaperones in neuronal and endocrine diseases

• Redox sensing and control in adrenal and gonadal steroidogenesis

Centre for Biochemical Pharmacology

• Understanding the role of inflammation during pregnancy

• Bioengineering 3D in vitro models to study chronic inflammation

• Investigating why chronic inflammatory diseases fail to resolve

• Developing an arthritic joint on a chip

• Development of layer-by-layer microcapsules for delivery of therapeutics

• Development of disease responsive promoters for application in gene therapy

• Using machine learning to correlate mass spectrometric and genomic data to establish disease mechanisms in chronic inflammatory disorders

• Understanding the cellular and immunological mechanisms elicited by pro-resolving mediators in infections

• Determining the mechanisms that regulate enzyme activity and lipid mediator biosynthesis

Centre for Clinical Pharmacology

• AI for precision medicine biomarker discovery in immune-mediated inflammatory diseases

Centre for Microvascular Research

• Myocardial regeneration and repair

• The control of endothelial junctions by intracellular trafficking

• Immunomodulatory roles of organotypic and disease-associated endothelial cells

• Lymph node stromal reprogramming: A Focus on Metabolism, Cytokines, and Inflammation

• Elucidating the role of exosomal miRNAs in the progression of heart failure

• The role of syndecans in inflammation and angiogenesis

• The pathophysiology of atypical chemokine receptors

• Mechanisms in neutrophil extravasation

Centre for Translational Medicine & Therapeutics

• Roles of C-type natriuretic peptide in cardiovascular health and disease

• The role of Bruton Tyrosine kinase (BTK) in ischaemia-reperfusion injury and shock

• Immunotransmitters to define acute and chronic inflammation

• Impact of metabolic ageing in neurodegeration

Centre for Advanced CV Imaging

• Artificial intelligence applications in Cardiac Magnetic Resonance and Cardiac CT

• Radiomics in cardiac imaging – towards personalised medicine

• Economic evaluations in cardiac imaging

Centre for CV Medicine & Devices

• Translational stem cell therapy for cardiovascular disease

• The non-canonical pathway for NO: mechanisms and therapeutics

• Sex differences in cardiovascular disease

• The microbiome and cardiovascular disease

• AI approach to coronary plaque characterisation from intracoronary imaging

• Non-invasive imaging technology for physiologic assessment of coronary artery disease

• Renal handling of nitrate and nitrite

• Effect of diabetes on nitrite-derived NO production

• Proteomics based druggable target discovery in cardiovascular diseases

• Role of intracellular chloride channels in vascular pathobiology

• Platelet dysfunction in pulmonary hypertension

• Endothelial cell metabolism in vascular homeostasis

• Role of endothelial mitochondria in the haemodynamic shear stress response

• Mitochondrial metabolism and function in angiogenesis

The scheme is open to any nationality and covers salary plus travel and family allowances for two years. Candidates need to have a PhD and must not have resided in the United Kingdom for more than 12 months in the past three years. For detailed information, take a look at the 2019 Guide for Applicants.

The MSCA IF 2020 call opens in April and closes on 9th September 2020, with successful projects starting in summer 2021.

** DEADLINE EXTENDED ** The deadline for receipt of Expressions of Interest is midnight on 31st May 2020, British Summer Time. For the application form and instructions, click here.