08/11/2018

INPhINIT Doctoral Fellowship Programme hosting offer: TRANSLATIONAL RESEARCH IN REPRODUCTIVE AND METABOLIC MEDICINE: FOCUS ON POLYCYSTIC OVARIAN SYNDROME (PCOS)


  • OFFER DEADLINE
    06/02/2019 00:00 - Europe/Brussels
  • EU RESEARCH FRAMEWORK PROGRAMME
    Not funded by an EU programme
  • LOCATION
    Spain, Córdoba
  • ORGANISATION/COMPANY
    IMIBIC (Maimonides Biomedical Research Institute)
  • LABORATORY
    https://www.imibic.org/grupo/22

IMIBIC HOSTING OFFER:

La Caixa INPhINIT INCOMING Doctoral Fellowship Programme

CENTRE DESCRIPTION

IMIBIC, located in Cordoba, southern Spain, is a partnership between the University of Cordoba (UCO) and the Reina Sofia University Hospital. IMIBIC offers a multidisciplinary environment focused on results-oriented research and based on precision medicine and excellence in science. IMIBIC is accredited with the Excellence distinction from the National Institute of Health Carlos III and the “HR Excellence in Research” by the EC.

The Institute is structured in 44 research groups that cooperate in the implementation of five scientific programmes. IMIBIC offers an active environment in which to conduct high-level scientific research. Regular seminars and research events offer the opportunity to meet with national and international experts covering a diverse range of topics in biomedicine. Advanced training of our PhD students is provided primarily through the Doctoral Program in Biomedicine (UCO), hosted at the IMIBIC and integrated by leading scientists from the University and the Hospital. Results from research activities are exposed yearly in the IMIBIC Young Investigator Meetings, providing an ideal environment to strengthen the skills and knowledge of young scientists and to foster translational research by bringing together experimental basic and medical sciences.

IMIBIC is young and fast growing research center. It operates in a brand new building located within the UCO Health Sciences Campus and next to the University Hospital. It hosts over 600 researchers, and offers the latest technology, equipment and laboratories to support the technical needs of the research community.

Cordoba is a medium sized city located in the hearth of Andalusia, with excellent transport connections to the main cities of Spain and both to the Mediterranean and Atlantic coasts. Rich in history and culture, Cordoba is a friendly and welcoming city, with high standard of living, making it an ideal location for international students wishing to carry out their doctoral studies in Spain.

GROUP LEADER

Prof.Manuel Tena-Sempere (fi1tesem@uco.es)

RESEARCH PROJECT/RESEARCH GROUP

IMIBIC group GC10: https://www.imibic.org/grupo/22

POSITION DESCRIPTION

The group “Hormonal Regulation of Energy Balance, Puberty & Fertility” is a consolidated research group at the Maimonides Biomedical Research institute of Cordoba - IMIBIC (Cordoba, Southern Spain). IMIBIC is a modern Biomedical Research Institute that holds the Excellence distinction from the Spanish Institutes of Health (ISCIII).

The research group is composed by 19 members, with 3 senior scientists, 6 pre-doctoral fellows, 7 postdoctoral researchers and 3 technicians. The group’s expertise lies on Reproductive and Metabolic Neuroendocrinology, with particular interest on the neuroendocrine regulation of energy homeostasis, puberty and the reproductive axis, and the reciprocal interplay between these key body functions. Our ultimate aim is to understand the basis for alterations of puberty and fertility linked to severe metabolic disturbances, from obesity to anorexia, and to decipher the mechanisms of metabolic perturbations associated with gonadal dysfunction.

Our team has a strong drive for translational research, which has materialized in various projects addressing prevalent human diseases, including polycystic ovary syndrome (PCOS), pubertal alterations, obesity and related metabolic perturbations. We use suitable preclinical models, including genetically-modified lines, and a wide arsenal of analytical techniques, such as in vivo neuro-hormonal studies, gene/protein expression analyses and virogenetic and optogenetic manipulation of neuroendocrine pathways. Expression analyses include high throughput techniques for large-scale detection of nucleic acids and proteins in tissues and biofluids (including blood), allowing the conduction of biomarker discovery projects.

Such combination of scientific goals and analytical approaches would permit the appointed PhD student to obtain an integral and highly qualified formation in biomedical research, particularly in areas related with the pathophysiology of puberty, reproduction and metabolism.

Job position description:

A position is offered for a talented student to implement a doctoral research project involving pathophysiological and translational studies on polycystic ovary syndrome (PCOS). These will involve the use of rodent models of PCOS, where pathophysiological mechanisms and eventual novel therapeutic strategies will be addressed, and analyses in human samples from PCOS patients, where biomarker discovery programs are currently running in the host group. The overall aim of this program, to be joined by the PhD student, is to deepen our knowledge of the mechanisms of the disease and to identify molecular markers (and eventual therapeutic options) of PCOS, for a better stratification and management of affected women.

This project will be conducted in the lab areas of our group at IMIBIC, fully equipped for molecular/neuroendocrine research on metabolism, puberty and reproduction. Our team has also full access to the core facilities of IMIBIC, with modern animal services and technical platforms of the Central Support Unit (UCAIB), as well as the Central Service for Support of Research of UCO, including Advanced Imaging, Proteomics & Genomics.

IMIBIC offers an ideal environment for biomedical research of excellence, of great value for the PhD fellow. Academic training of the student will be founded on the Doctoral Program in Biomedicine of UCO, hosted by IMIBIC. In addition, our series of lab-meetings, seminars and research events (including yearly meetings of Young Investigators) will provide unique opportunities to interact with peers and leading scientists, from a range of areas in biomedicine.

In this stimulating context, the fellow joining our group will complete a full doctoral program, leading to the acquisition of the PhD within the duration of the grant. This formative dimension is reinforced by the ample opportunities of interaction and short-term visits provided by our network of national and international collaborators.

Eligibility Criteria

1) At the call deadline (6th Feb 2019), applicants must be in the first four years (full-time equivalent research experience) of their research careers and not yet have been awarded a doctoral degree.

2) At the time of recruitment, candidates must comply with one of the following options:

  • To have completed the studies that lead to an official university degree adapted to the European Higher Education Area awarding 300 ECTS credits, of which at least 60 ECTS credits must correspond to master level.
  • To have completed a degree in university not adapted to the European Higher Education Area that gives access to doctoral studies. The verification of an equivalent level of studies to the ones mentioned above will be made by the university when the admission procedure starts.

3) Candidates must not have resided or have carried out their main activity (work, studies, etc.) in Spain for more than 12 months in the 3 years immediately prior to the call deadline (6th Feb 2019). Short stays, such as holidays, done in a country other than their country of usual residence (where they carried out their main activity), will be considered as time spent in their country of usual residence.

4) Candidates must have a demonstrable level of English (B2 or higher).

5) Only candidates whose applications meet all the requirements of the call may be accepted.

 

You can find this offer via the Offer Finder, available at: https://hosts.lacaixafellowships.org/finder

Select “IMIBIC – Maimonides Biomedical Research Institute to Cordoba” from the dropdown list under “RESEARCH CENTER”

You can also search the position by its title "TRANSLATIONAL RESEARCH IN REPRODUCTIVE AND METABOLIC MEDICINE: FOCUS ON POLYCYSTIC OVARIAN SYNDROME (PCOS)" under "SEARCH BY PROJECT TITLE / JOB POSITION TITLE".

 

How to Apply:

If you want to apply for an INPhINIT fellowship, click on the link below to create your personal account and fill in the on-line application form: https://www.lacaixafellowships.org/index.aspx

 

Schedule:

6 February 2019: Application deadline.

20 February 2019: Deadline for submitting the language certificate.

23 April 2019: Notification of the shortlist results.

28 and 29 May 2019: Face-to-face interviews in Barcelona.

4 June 2019: Publication of the final list of selected candidates.

4 June 2019 to 5 July 2019: Matching between the research centres – fellows.

 

More Information:

Call for applications:

https://obrasociallacaixa.org/en/investigacion-y-becas/programa-de-becas-de-posgrado/inphinit/incoming

Programme Rules: https://obrasociallacaixa.org/documents/10280/590054/inphinit_incoming_2019_en.pdf/2fa7e823-a7c7-22d8-98a7-dd14a0d0171f

Email:

international@imibic.org