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Doctoral INPhINIT Fellowships - Induced pluripotent stem cell reprogramming: Mechanisms and factors involved for its application in regenerative medicine and disease modelling.

The Human Resources Strategy for Researchers
10/11/2022

Hosting Information

Offer Deadline
EU Research Framework Programme
Not funded by an EU programme
Country
Spain
City
Málaga

Organisation/Institute

Organisation / Company
IBIMA
Department
IBIMA HE-01Cell reprogramming (iPSCs) and cell models of disease for biomedical applications.
Is the Hosting related to staff position within a Research Infrastructure?
No

Contact Information

Organisation / Company Type
Public Research Institution
Website
Email
opi@ibima.eu
State/Province
Málaga
Postal Code
29590
Street
Severo Ochoa, 35

Description

We are looking for candidates to apply to IBIMA’s research positions, funded by La Caixa “Incoming Doctoral INPhINIT Fellowships” call 2023 (https://fundacionlacaixa.org/en/inphinit-doctoral-fellowships-incoming). Clicking on this link you will find the call’s guidelines (including application rules and conditions).

The offer:

  • Hosting institution: Instituto de Investigación Biomédica de Málaga (IBIMA. Plataforma BIONAND), Málaga (Spain)
  • Leader: PhD. Elena Gonzalez-Muñoz
  • Study area: Cellular Biology
  • Title: Induced pluripotent stem cell reprogramming: Mechanisms and factors involved for its application in regenerative medicine and disease modelling.
  • Duration: 3 years
  • Grant amount: Up to 125.400 € + training

 

Activity and Training: The reprogramming of somatic cells to induced pluripotent cells (iPSCs) has enabled the direct modeling of human disease and basically promises to revolutionize regenerative medicine. In this project we want to make a deep understanding of the pluripotent state analyzing the oocyte-based reprogramming to study the transcriptional, proteomic and epigenetic changes to define distinctive pluripotent states and their functional consequences. The identification of pluripotent states with less epigenetic memory, better culture conditions and greater potential for differentiation will be used in this project for the generation of reliable 3D organoid-based cellular models of neurodegenerative diseases (Friedreich´s Ataxia and Multiple Sclerosis) to study molecular pathways involved and potential alternative treatment strategies.

In order to be eligible, candidates must:

  • Be in the first four years (full-time equivalent research experience) of their research careers and not yet have been awarded a doctoral degree.
  • Hold a higher education degree that makes them eligible to enrol in a doctoral programme.
  • Have resided in Spain for less than 12 months in the last 3 years.
  • Demonstrable level of English (B2 or higher).

Desired candidate profile:

  • Student in Life Sciences or Biomedicine
  • Desired experience (not essential):
    • Techniques/skills: Cell culture, molecular biology, confocal microscopy and flow cytometry, methodological and statistical analysis on Biomedical Research, among others.

Should you be interested in applying to this offer, do not hesitate to contact IBIMA’s International Projects Office (opi@ibima.eu). We will be happy to help.