02/09/2022
The Human Resources Strategy for Researchers

Postdoc (M/F) in RNA biophysics and structural biology

This job offer has expired


  • ORGANISATION/COMPANY
    CNRS
  • RESEARCH FIELD
    Biological sciencesBiological engineering
    ChemistryBiochemistry
    PhysicsBiophysics
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    14/10/2022 23:59 - Europe/Brussels
  • LOCATION
    France › STRASBOURG
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    35
  • OFFER STARTING DATE
    01/11/2022

OFFER DESCRIPTION

- large-scale RNA production and purification
- RNA chemical probing
- biophysics (fluorescence, spectroscopy, mass spectrometry, calorimetry, biosensors)
- structural biology (X-ray crystallography, cryo-EM, NMR)
- molecular modeling

The candidate will be in charge of studying the structure of a long non-coding RNA involved in solid cancers, as well as characterizing its interaction with potential partners (proteins, RNPs) in order to identify its mechanism of action and ways to interfere with its biological role.

The laboratory "Architecture and Reactivity of RNA", CNRS UPR 9002, is a multidisciplinary laboratory where the research themes developed are related to the biology of the RNA world.
The candidate will be hosted in the team "Structure and Dynamics of Biomolecular Machines" which includes 6 CNRS and INSERM researchers and 3 CNRS engineers as well as students and interns. The team has a strong expertise in biophysics and structural biology of RNA (NMR, crystallography and cryoEM) and relies on a biophysics platform available in the laboratory as well as on an easy access to the large infrastructures needed in structural biology.

Translated with www.DeepL.com/Translator (free version)

More Information

Eligibility criteria

- good knowledge of RNA biology
- working knowledge of the Linux operating system
- expertise in RNA solution mapping
- expertise in biophysics
- expertise in structural biology (NMR or X-ray crystallography or cryoEM)

Web site for additional job details

Required Research Experiences

  • RESEARCH FIELD
    ChemistryBiochemistry
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    PhysicsBiophysics
  • YEARS OF RESEARCH EXPERIENCE
    None
  • RESEARCH FIELD
    Biological sciencesBiological engineering
  • YEARS OF RESEARCH EXPERIENCE
    None

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Chemistry: PhD or equivalent
    Physics: PhD or equivalent
    Biological sciences: PhD or equivalent
  • REQUIRED LANGUAGES
    FRENCH: Basic
Work location(s)
1 position(s) available at
Architecture et Réactivité de l'ARN
France
STRASBOURG

EURAXESS offer ID: 832519
Posting organisation offer ID: 31576

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