31/08/2022

Postdoctoral position in organic chemistry – FlowCAP project

This job offer has expired


  • ORGANISATION/COMPANY
    CEA Saclay
  • RESEARCH FIELD
    Chemistry
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
    Recognised Researcher (R2)
    Established Researcher (R3)
    Leading Researcher (R4)
  • APPLICATION DEADLINE
    28/11/2022 00:00 - Europe/Athens
  • LOCATION
    France › Saclay
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • OFFER STARTING DATE
    01/02/2023

OFFER DESCRIPTION

In the context of personalized medicine where treatment must be adapted to the patient, antibodies and more particularly ADCs (antibody-drug conjugates) are expanding rapidly, with 11 compounds on the market in 2021 and more than 300 in clinical trials. However, despite their undoubted interest, many challenges remain particularly for controlling the number of cytotoxic molecules bound to the antibody and for determining their precise binding sites.

FlowCAP project is an innovative project aiming at improving current antibody-cytotoxic compound coupling methodologies in order to access different ADCs via innovative robust processes. The use of flow chemistry will ultimately allow the development of safe production of large quantities of ADCs. They could also serve as a starting point for the development of new ADCs, functionalized by drugs of various kinds or by therapeutic radioisotopes, and thus push the ADC concept even further.

More Information

Offer Requirements

Specific Requirements

Candidates should have:

- Strong skills in organic chemistry

- A PhD in organic chemistry

- Excellent knowledge, both written and oral, of English

- A real skill to work in large collaboration and autonomously

- Strong interpersonal, organizational and communication skills are a must.

Work location(s)
1 position(s) available at
CEA Saclay
France
Saclay

EURAXESS offer ID: 830877
Posting organisation offer ID: 107258

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