RESEARCHER PROFILEFirst Stage Researcher (R1)Recognised Researcher (R2)Established Researcher (R3)Leading Researcher (R4)
APPLICATION DEADLINE28/11/2022 00:00 - Europe/Athens
LOCATIONFrance › Saclay
TYPE OF CONTRACTTemporary
OFFER STARTING DATE01/02/2023
In the context of personalized medicine where treatment must be adapted to the patient, antibodies and more particularly ADCs (antibody-drug conjugates) are expanding rapidly, with 11 compounds on the market in 2021 and more than 300 in clinical trials. However, despite their undoubted interest, many challenges remain particularly for controlling the number of cytotoxic molecules bound to the antibody and for determining their precise binding sites.
FlowCAP project is an innovative project aiming at improving current antibody-cytotoxic compound coupling methodologies in order to access different ADCs via innovative robust processes. The use of flow chemistry will ultimately allow the development of safe production of large quantities of ADCs. They could also serve as a starting point for the development of new ADCs, functionalized by drugs of various kinds or by therapeutic radioisotopes, and thus push the ADC concept even further.
Candidates should have:
- Strong skills in organic chemistry
- A PhD in organic chemistry
- Excellent knowledge, both written and oral, of English
- A real skill to work in large collaboration and autonomously
- Strong interpersonal, organizational and communication skills are a must.
EURAXESS offer ID: 830877
Posting organisation offer ID: 107258
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