23/06/2022

PhD IN BIOMOLECULAR SCIENCE


  • ORGANISATION/COMPANY
    University of Campania "Luigi Vanvitelli"
  • RESEARCH FIELD
    ChemistryStructural chemistry
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    15/07/2022 14:00 - Europe/Athens
  • LOCATION
    Italy › Caserta
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/12/2022

OFFER DESCRIPTION

The PhD program in Biomolecular Sciencesis a research doctorate of the University of Campania Luigi Vanvitelli in Caserta-Naples, Italy. The program is multidisciplinary and based on a well-balanced combination of research activity with access to the most modern technological platforms, theoretical courses, internal seminars and participation to national and international conferences. The official language of the Doctorate program is English. Research and training activities will take place in the Department of Environmental, Biological and Pharmaceutical Sciences and Technologies of the University of Campania Luigi Vanvitelli, via Vivaldi, Caserta and in the CNR Institutes of Genetics and Biophysics A. Buzzati-Traverso, Institute of Biochemistry and Cell Biology, and Biostructures and Bioimaging of Napoli. All these institutions provide an international and very stimulating research environment for the students. The students will spend part of their doctorate (at least 3 months) in research groups abroad.

 

Your project: Neurodegenerative diseases are debilitating and untreatable conditions that are fatally destined to increase the socio-sanitary burden because of ageing of population. Alzheimer’s disease (AD) represents the principal cause of dementia in developed countries. Experimental studies suggested the possibility of a link between cellular prion protein (PrPC) and AD. PrPCis a high affinity receptor for Aβ oligomers (Aβ(O)) and it mediates Aβ-induced neurotoxicity and thus plays an important role in AD pathogenesis. Recently, a series of trehalose-conjugated peptides (TCPs) that are neuroprotective and able to inhibit Aβ40/42 fibrillogenesis, blocking the early stage of Aβself-assembly have been designed and synthetized. In this scenario, the main goal of the proposed Ph.D project will be to target the abnormal Aβ(O)/HuPrPCinteraction mechanisms by exploring the ability of short TCPs to prevent Aβ(O) formation. The research activity will largely employ NMR techniques, either in solution or in semi-solid state, that will be complemented by High Resolution Mass Spectrometry (HR-MS), circular dichroism (CD), Thioflavin-T (ThT) fluorescence, Electronic Spin Resonance (ESR) approaches (CNR-IC).

 

Supervisor: Prof. Luigi Russo. Email: Luigi.russo2@unicampania.it. Publications: Scopus Author ID: 23036548500; https://orcid.org/0000-0002-1577-176X. Candidates should contact the supervisor to arrange a preliminary interview by Skype as soon as possible.

 

Your qualification: Master degree in biology (and related fields) or equivalent obtained in countries other than Italy. Preference will be given to candidates with experience in Chemistry.

 

Our offer: 3-year PhD student position with scholarship from December 2022

 

Evaluation Criteria

- Curriculum assessment concerns:

a) Master degree thesis (pertinence with Ph.D. topics, final grades);

b) certified knowledge of Foreign languages;

c) research and study abroad;

d) scholarships;

e) post graduate qualifications;

f) publications, conference abstracts, reference letters.

g) a written research project on the topics of the PhD program following the instructions reported in the call https://www.unicampania.it/RipartizioniFS/RAG/Dottorati_di_Ricerca/38/Bando_38_ciclo_-_con_schede_rev.pdf

 

 

- The oral testwill concern a discussion on the qualifications and the research project submitted and will be conducted electronically via Skype (or another similar tool).

 

How to apply

Contact the supervisor for a preliminary interview as soon as possible and then apply online by following the instructions reported in the call https://www.unicampania.it/RipartizioniFS/RAG/Dottorati_di_Ricerca/38/Bando_38_ciclo_-_con_schede_rev.pdf

More Information

Benefits

The winner of the position will receive a scholarship of 16,243.00euro which will be prepaid every month. The amount of the scholarship will be increased by 50% for research visits outside of Italy.

Eligibility criteria

- Academic degree: master degree or equivalent corresponding to the second level of studies.

- Mobility rule: Applicants can be from any Country, but should have received their degree from a University located outside of Italy.

Selection process

We offer a 3-year PhD position, available upon admission to the PhD program in Biomolecular Sciences of the University of Campania “Luigi Vanvitelli”. Candidates will be selected on the basis of an interview and will be next invited to apply to the recruitment call. In case of positive outcome of the recruitment, the position will be available starting in December 2022.

Additional comments

What we are looking for

The ideal candidate has a Master degree in Chemistry or Biology (and related fields) and a background in chemistry and structural biology. Expertise in Structural and Molecular Biology (i.e. protein expression and purification, cellular biology) and Bioinformatics are also welcome. Willingness to work with interdisciplinary approaches and communication and organizational skills are also appreciated. Finally, fluent spoken and written English language knowledge is required.

 

How to apply

Please send your pre-application as a single pdf in English. The application should include a cover letter (summarizing your experience, your future vision and your interest in the project), a CV of no more than 4 pages (and including the list of publications) and relevant certificates (degree certificates, etc.) to Prof. Luigi Russo (luigi.russo2@unicampania.it).

The deadline for pre-application is 04.07.2022

Short listed candidates will be invited for an online Skype interview.

For queries, email to luigi.russo2@unicampania.it

 

Web site for additional job details

https://www.unicampania.it

Required Research Experiences

  • RESEARCH FIELD
    ChemistryStructural chemistry
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Chemistry: Master Degree or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Excellent

Skills/Qualifications

The ideal candidate has a Master degree in Chemistry or Biology (and related fields) and a background in chemistry and molecular biology. Expertise in Structural Chemistry, Structural biology and bioinformatics are also welcome. Willingness to work with interdisciplinary approaches and communication and organizational skills are also appreciated. Finally, fluent spoken and written English language knowledge is required.

Specific Requirements

Chemical Biology, Structural Biology, Neurodegenerative diseases, Nuclear Magnetic Resonance

Map Information

Job Work Location Personal Assistance locations
Work location(s)
1 position(s) available at
University of Campania "Luigi Vanvitelli"
Italy
Caserta
81100
Via Vivaldi 43

EURAXESS offer ID: 803571

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