29/04/2022

Innovative nanosystems for the theranostics of atherosclerosis

This job offer has expired


  • ORGANISATION/COMPANY
    Università degli Studi di Genova
  • RESEARCH FIELD
    Medical sciences
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
    Recognised Researcher (R2)
    Established Researcher (R3)
    Leading Researcher (R4)
  • APPLICATION DEADLINE
    23/05/2022 23:59 - Europe/Brussels
  • LOCATION
    Italy
  • TYPE OF CONTRACT
    To be defined

OFFER DESCRIPTION

The main objective is the biological validation of two formulations based on nanosystems: one is designed and fabricated for the diagnosis of the atherosclerotic plaque with the risk to present clinical evidences; the other, for therapeutic purposes, is intended for the treatment/limitation of the evolution of the plaque.For the first part the activity will be based on photoacoustic nanoparticles, whereas the second part, polymeric nanoparticles loaded with monoclonal antibodies and externally
engineered with antibodies specific for markers of the early-state plaque will be used. These two nanosystems will be validated with in vivo imaging for the diagnostic purposes in ApoE-/- mice. Furthermore, in vitro studies on different cell lines (endothelial, smooth muscle cells, and macrophages) will be used for testing their
therapeutic potential

More Information

Eligibility criteria

The qualification to apply every selection is specified in the notice for each research program. To apply for research grants: https://concorsi.unige.it/home
Applications and CVs sent by e-mail are not accepted


Eligible destination country/ies for fellows:

  • Italy

Eligibility of fellows: country/ies of residence:

  • EUROPE

Eligibility of fellows: nationality/ies:

  • EUROPE

Selection process

evaluation of presented titles and interview on the subjects specified by the notice

Web site for additional job details

Work location(s)
1 position(s) available at
Università degli Studi di Genova
Italy

EURAXESS offer ID: 779466
Posting organisation offer ID: 209775

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