Innovative nanosystems for the theranostics of atherosclerosis
This job offer has expired
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ORGANISATION/COMPANYUniversità degli Studi di Genova
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RESEARCH FIELDMedical sciences
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RESEARCHER PROFILEFirst Stage Researcher (R1)Recognised Researcher (R2)Established Researcher (R3)Leading Researcher (R4)
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APPLICATION DEADLINE23/05/2022 23:59 - Europe/Brussels
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LOCATIONItaly
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TYPE OF CONTRACTTo be defined
OFFER DESCRIPTION
The main objective is the biological validation of two formulations based on nanosystems: one is designed and fabricated for the diagnosis of the atherosclerotic plaque with the risk to present clinical evidences; the other, for therapeutic purposes, is intended for the treatment/limitation of the evolution of the plaque.For the first part the activity will be based on photoacoustic nanoparticles, whereas the second part, polymeric nanoparticles loaded with monoclonal antibodies and externally
engineered with antibodies specific for markers of the early-state plaque will be used. These two nanosystems will be validated with in vivo imaging for the diagnostic purposes in ApoE-/- mice. Furthermore, in vitro studies on different cell lines (endothelial, smooth muscle cells, and macrophages) will be used for testing their
therapeutic potential
More Information
Eligibility criteria
The qualification to apply every selection is specified in the notice for each research program. To apply for research grants: https://concorsi.unige.it/home
Applications and CVs sent by e-mail are not accepted
Eligible destination country/ies for fellows:
- Italy
Eligibility of fellows: country/ies of residence:
- EUROPE
Eligibility of fellows: nationality/ies:
- EUROPE
Selection process
evaluation of presented titles and interview on the subjects specified by the notice
Web site for additional job details
EURAXESS offer ID: 779466
Posting organisation offer ID: 209775
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