27/04/2022

Post Doc postion medicinal chemistry

This job offer has expired


  • ORGANISATION/COMPANY
    Institut Pasteur de Lille
  • RESEARCH FIELD
    ChemistryOrganic chemistry
  • RESEARCHER PROFILE
    Established Researcher (R3)
    Recognised Researcher (R2)
    Leading Researcher (R4)
  • APPLICATION DEADLINE
    27/05/2022 21:00 - Europe/Brussels
  • LOCATION
    France › lille
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    35
  • OFFER STARTING DATE
    01/06/2022

OFFER DESCRIPTION

Drugs and molecules for Living Systems– U1177 – Inserm-Institut Pasteur de Lille –Université de Lille – Lille, France

 

The research team Drugs and Molecules for Living Systems, (INSERM, Institut Pasteur de Lille and University of Lille), specialized in drug discovery, medicinal chemistry, screening and pharmacokinetics (www.deprezlab.fr) is offering a 18-month postdoc position.

 

The candidate will be recruited by The Institut Pasteur de Lille in our laboratory that gathers chemists and biologists to design new drugs in an inspiring and stimulating environment.

 

The aim is to design, synthesize and perform multiparametric optimization of inhibitors of the protease 3CL of the coronavirus SARS-CoV2.

 

Missions:

  • Design & synthesis of 3CLpro inhibitors
  • Multiparametric optimization & Interpretation of biological and ADME results (SAR)
  • Writing of ELN, of protocols, Reagents ordering
  • Preparation/ writing of publications, posters, oral communication
  • Participation to shared lab tasks
  • Mentoring and supervising students

 

Qualifications requirements:

  • Experience with multi step synthesis
  • Experience with multiparametric optimization
  • Good knowledge of medicinal chemistry
  • Experience in using modern analytic instrumentation, including running and interpretation of NMR-spectra (1D and 2D) and also Mass-spectrometry
  • Experience in specialized softwares and databases, ELNs, Biovia Draw or Chem Draw, Reaxys or SciFinder, Pubmed
  • Experience in molecular modeling particularly in docking simulations (MOE or Pymol) would be a plus
  • Excellent knowledge of Excel, Word, Powerpoint
  • Publication writing skills
  • Good command of both oral and written English

 

In order to achieve success in the research, the candidate should demonstrate rigor, creativity, initiative, and excellent team work.

 

Required degree and experience:

  • a PhD in organic chemistry or medicinal chemistry
  • a minimum of 1 year postdoc experience in medicinal chemistry

 

More Information

Web site for additional job details

Work location(s)
1 position(s) available at
institut pasteur de lille
France
lille

EURAXESS offer ID: 777881

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