POSTDOC IN ORGAN-ON-CHIPS

OFFER DESCRIPTION

We are looking for a post-doc to join our team for 1.5 years for our work in projects with organs on chips and extracellular vesicles. The project is aimed to develop PDMS-free chips with integrated sensors focusing on lung on chip and gut on chip. The models are used to test extracellular vesicles (EV) as drug delivery vehicles and research microbiota - host communication mechanisms. Therefore, a large portion of this work will be done using BSL2 and BSL3 equipment at Latvian Biomedical Research and Study Centre and 650+ m² ISO9001-accredited cleanroom facilities allowing microfluidic device fabrication at facilities of Institute of Solid State Physics.

Cellbox Labs (https://www.cellboxlabs.com/) is one of the top biotech startups from Latvia that develops unique organ on chip technology that enables to create more accurate in-vitro models.

Job responsibilities

• Functional device experiment design and execution.
• Lung in chip and gut on chip functionalization with stable cell lines, primary cell lines and organoids differentiated from patient derived iPSC.
• Viable, anaerobic patient derived microbiota cultivation within gut on chip and analysis.
• Therapeutic extracellular testing within lung on chip.
• Thorough experiment documentation and report preparation.
• Writing scientific publications and present results in international conferences.
• Support, supervision and mentoring of PhD students.
• Work closely together with engineering team.

Job requirements

Essential

• PhD in a field related to use of organ on chip technology or similar technology obtained not more than 7 years ago.
• Demonstrated expertise in innovative organ on chip applications.
• Strong research background in at least one of the following: microfluidics, different in vitro platforms, cell biology, molecular biology.
• Experience in work with stable cell lines, primary cell lines, iPSC and organoids.
• An ability to work in a fast-paced, cross-functional group environment.
• Ability to manage multiple assignments effectively in a quickly evolving environment.
• Must be eligible to work and travel in EU without restrictions.

Desirable

• Experience with iPSC reprogramming and differentiation
• Previous experience with microbiota within gut on chip is a plus.
• Previous experience with EVs is a plus.
• Previous experience in cancer research is a plus.

Benefits

• Approximately 40 000 € annual gross salary.
• Innovative and positive working environment.
• 4 week/year paid vacation.
• Health insurance.
• Professional and personal development opportunities .
• Lecturer position opportunities at university.

Selection process

Please send your application to gatis.mozolevskis@cellboxlabs.com and include:

• A motivation/application letter
• A detailed CV including scientific achievements (publications, conference presentations, awards etc.)
• A photocopy of the candidate’s PhD degree.

We are an equal opportunity employer and value diversity and inclusion at our institute. We encourage applications from all sections of society.

Applications will be treated on first come, first served basis.