ORGANISATION/COMPANYUniversity College Cork
RESEARCH FIELDBiological sciencesChemistry › BiochemistryMedical sciences
RESEARCHER PROFILEFirst Stage Researcher (R1)Recognised Researcher (R2)
APPLICATION DEADLINE12/05/2022 12:00 - Europe/London
LOCATIONIreland › Cork
TYPE OF CONTRACTTemporary
HOURS PER WEEK39
2 Years, Fixed-Term, Whole-time Post
The Research Institute
APC Microbiome Ireland was formed in 2003 with funding from Science Foundation Ireland and in conjunction with key industry partners. It represents a seamless collaboration between UCC, Teagasc, Moorepark and CIT. It is widely recognised that our microbiome (community of bacteria/viruses and fungi that live in and on our bodies) plays an important role in human health and has become one of the most dynamic, complex and exciting areas of research in both food and pharmaceutical arenas. Over the last decade the APC has established itself as one of the leading global centres in gut microbiota research. The APC has made several landmark discoveries and has published over 3,500 research articles in peer-reviewed journals, generating many journal covers and associated editorials. The APC comprises over 300 individuals, from the scientific PI’s (the APC Faculty) funded by the partner Institutions, the management team, and a dedicated group of research scientists, research assistants and postgraduate’s students.
The dairy fermentation industry is reliant on the application of robust starter cultures of Streptococcus thermophilus and Lactococcus lactis. The most prominent opponent to successful fermentations is the presence of bacterial viruses called bacteriophages, or phages. The proposed project PHARM, is an ambitious project that aims to elucidate the specific nature of the saccharidic receptors recognised by Streptocococcus thermopilus phages through a combined genetic and biochemical approach. Furthermore, it is planned to derive the 3-dimensional structure of phage-encoded carbohydrate binding proteins to define their specific role and relative importance in the initial binding steps of a phage to its streptococcal host. The generated knowledge will allow tools to be developed for the rapid classification of dairy streptococcal strains and to link these to phage sensitivity predictions. Ultimately, this will allow the starter culture industry to provide rational strain selections, rotations or blends to the dairy industry, limiting phage proliferation in the fermentation environment. In turn, this will reduce the phage problem to manageable and predictable levels, reduce the amount of food waste and down-graded products thereby increasing food quality and security.
The Post-Doctoral Researcher would be expected to support the research activities of the Pharm project including execution of individual project goals and guidance of PhD student to ensure the timely execution of the project goals, while also contributing the communication of the research findings emanating from the research.
Qualifications and Experience Required
Candidates for the postdoctoral position should have a PhD in Molecular Microbiology, Genetics, Biochemistry, Bioinformatics or related fields. The expertise and relevant experience of candidates should be supported by evidence of peer-reviewed publications in reputable scientific journals.
UCC is an accredited research organisation and as such can form hosting agreements with third country nationals (and non-EEA nationals) for the purpose of conducting research in University.
Post Duration: 2 years
Salary: €39,522 - €46,906 p.a. (IUA Salary Scale)
Project: The sweet tooth of a bacterial virus: Unravelling Phage-Host Attachment and Recognition Modalities (PHARM) in the dairy bacterium Streptococcus thermophilus
For an information package including further details of the post see https://ore.ucc.ie/. Job ID: 055591.
Informal enquiries can be made in confidence to Professor Jennifer Mahony, School of Microbiology Tel: + 353 (0) 21 4902730; Email: firstname.lastname@example.org.
Applications must be submitted online via the University College Cork vacancy portal (https://ore.ucc.ie/). Queries relating to the online application process should be referred to email@example.com, quoting the job-title and project name.
Candidates should apply, in confidence, before 12 noon (Irish Local Time) on Thursday, 12 May 2022. No late applications will be accepted.
UCC is committed to creating and fully embracing an inclusive environment where diversity is celebrated. As a University we strive to create a workplace that reflects the diversity of our student population where people from a wide variety of backgrounds learn from one another, share ideas, and work collaboratively. UCC is committed to being an employer that recognises the value of diversity amongst its staff. We encourage applicants to consult our policies at https://www.ucc.ie/en/edi/policies/ and initiatives at https://www.ucc.ie/en/edi/implementation/ and we welcome applications from everyone, including those who are underrepresented in the protected characteristics set out in our Equal Opportunities & Diversity Policy.
Please note that an appointment to posts advertised will be dependent on University approval, together with the terms of the employment control framework for the higher education sector.
UNIVERSITY COLLEGE CORK IS AN EQUAL OPPORTUNITIES EMPLOYER
EURAXESS offer ID: 772922
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