ORGANISATION/COMPANYEcole Normale Supérieure de Lyon
RESEARCH FIELDBiological sciences › BiologyChemistry
RESEARCHER PROFILERecognised Researcher (R2)Established Researcher (R3)
APPLICATION DEADLINE01/01/2022 00:00 - Europe/Athens
LOCATIONFrance › Lyon
TYPE OF CONTRACTTemporary
OFFER STARTING DATE01/02/2022
The successful candidate will be enrolled in a project focused on the investigation of an innovative and non-invasive approach to induce deep-tissue photodynamic therapy (PDT) with photosensitizer conjugated to nanoscintillators, nanoparticles able to down-convert X-rays into low energy photons that in turn will excite adjacent photosensitizers. As X-rays penetrate deeply into tissues, this approach could activate PDT at depth and potentially within larger tumours than PDT induce by light.
The core task in this project is to develop new and original polymer scaffolds for the surface functionalization of various nanoscintillators (rare earth fluorides, oxides, etc.). The polymer shell will allow to enhance the nanoscintillator stability, bring plasma compatibility and low immunogenicity, but also allow conjugation of the NS with suitable photosensitizers and fluorophores.
- PhD in Chemistry with strong background in experimental organic synthesis and characterization methods associated. Skills in the synthesis and characterization of polymers are desirable.
- Excellent spoken and written English communication skills
- Self-motivated, detail- and goal-oriented with excellent problem solving skills in a multi-disciplinary team
EURAXESS offer ID: 710762
Posting organisation offer ID: 101313
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