RESEARCH FIELDBiological sciencesEnvironmental science
RESEARCHER PROFILERecognised Researcher (R2)
APPLICATION DEADLINE25/11/2021 23:59 - Europe/Brussels
LOCATIONFrance › POITIERS
TYPE OF CONTRACTTemporary
HOURS PER WEEK35
OFFER STARTING DATE01/01/2022
The post-doc will be responsible for monitoring tick cell lines, performing infection and co-infection and characterising the cellular phenotypes. Methods include RT-qPCR, dual-RNAseq, FISH combined with electron microscopy.
The objective of the project is to identify the evolutionary mechanisms that drive extinction and reborn of mutualistic interactions using ticks (Ixodida, Acari) as ideal biological models to address this question. Ticks host nutritional symbionts that are essential for their growth and survival, but the origin of these symbionts varies considerably between host species and substitution of beneficial symbionts can occur (Gottlieb et al, 2015; Duron et al, 2018; Guizzo et al, 2017; Duron et al, 2017; Binetruy et al, 2020).
The project aims at deciphering the competition between Francisella and Coxiella symbionts using different approaches from genomics, transcriptomics, in vivo and in vitro imaging. The recruited post-doc will participate in this innovative program with a particular focus on in vitro experiments assessing the competitive abilities of the two beneficial symbionts.
The position is associated with the ANR-funded collaborative project MICROM “Microbial competition in mutualistic interactions with ticks”. The MICROM consortium, led by Olivier Duron, involves three teams (O. Duron MIVEGEC, Montpellier, F. Vavre LBBE, Lyon and D. Bouchon EBI, Poitiers) with considerable expertise in the field of endosymbiosis.
The post-doc will be part of the Ecology, Evolution & Symbiosis team of the EBI laboratory in Poitiers, which has a long experience in research on symbiosis. The post-doc will have access to the funding and infrastructures needed for this project, in a stimulating scientific environment. Regular exchanges and mobility are planned with the various project partners as well as with external collaborators such as the Tick Cell BioBank in Liverpool. At the CNRS, the post-doc will be under the responsibility of the project leader.
-We are looking for an autonomous and highly motivated candidate with a genuine interest in symbiosis research with expertise in the following areas:
• Cell culture
• Molecular biology
• Imaging approaches, cellular biology, histology. Experience in electron microscopy is a plus.
• Interested in acquiring expertise in experimentation with arthropods: care, injection, dissection
• Expertise in bioinformatics is a plus
Web site for additional job details
Required Research Experiences
RESEARCH FIELDBiological sciences
YEARS OF RESEARCH EXPERIENCE1 - 4
RESEARCH FIELDEnvironmental science
YEARS OF RESEARCH EXPERIENCE1 - 4
REQUIRED EDUCATION LEVELBiological sciences: PhD or equivalentEnvironmental science: PhD or equivalent
REQUIRED LANGUAGESFRENCH: Basic
EURAXESS offer ID: 699114
Posting organisation offer ID: 24900
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