16/06/2021

Doctoral Researcher (f/m/d)

This job offer has expired


  • ORGANISATION/COMPANY
    Helmholtz Centre for Infection Research
  • RESEARCH FIELD
    Biological sciencesBiology
    Chemistry
    Medical sciences
    Pharmacological sciences
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    25/07/2021 23:00 - Europe/London
  • LOCATION
    Germany › Braunschweig
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Part-time
  • HOURS PER WEEK
    19,5
  • OFFER STARTING DATE
    01/10/2021
  • REFERENCE NUMBER
    77/2021

OFFER DESCRIPTION

The PK/PD unit within the Department of Chemical Biology (CBIO) of Dr. Katharina Rox at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany is offering a position as

Doctoral Researcher (f/m/d)

Project title: PBPK modelling of novel anti-infectives

 

Project description:

The PK/PD unit within the Department of Chemical Biology (CBIO) aims to characterize novel anti-infectives and to bridge the gap between bench and bedside. The project aims to perform in silico analysis of re-purposed and novel compounds to establish pharmacokinetic (PK) and pharmacodynamic (PD) relationships from preclinical in vitro and in vivo data. The in silico analysis aims to translate dose-response relationships from animals to humans. Moreover, the in silico analysis will contribute to find the optimal dose for subsequent clinical trials. Finally, the methods developed in the project will advance PK/PD characterizations in the field.

 

Qualifications:

  • Master’s Degree / State examination in Pharmacy, Medicine, Pharmacology, Systems Biology, Computational Biology, Pharmaceutical Sciences, Chemical/Biomedical engineering or a related field within the life sciences
  • Excellent English communication skills (written and spoken)
  • Ability to work independently and as part of an international team
  • Excellent experimental and organizational skills
  • Strong analytical skills
  • Strong background in and solid understanding of pharmacology, preferably with a focus on anti-infectives
  • Experience in using HPLC-MS and analysis of MS data is a plus
  • Hands-on experience in using PBPK-modelling software

 

Disabled persons are given preference in the case of equal professional qualification. The HZI aims for professional equality between women and men. The position is suitable for part-time work.

 

Starting date: 1st October 2021 or later - Initial contract for 3 years

 

Salary: alike TVöD E13 (65%)

 

Probation period: 6 months

 

Published on: 16th June 2021

Closing date: 25th July 2021

 

Application: Applicants are required to complete the online application form here:

https://hzi.opencampus.net/ (Please select Job No. 77/2021).

 

For more details regarding the position, please contact Dr. Katharina Rox via email: Katharina.rox@helmholtz-hzi.de, or by phone: +49 531 6181-4409.

 

Further information about the institute and the research group can be found on the websites: https://www.dzif.de/en/working-group/pharmacokinetics-and-pharmacodynamics and https://www.helmholtz-hzi.de/en/nc/research/research-topics/anti-infectives/chemical-biology/team/

 

More Information

Work location(s)
1 position(s) available at
Helmholtz-Zemtrum für Infektionsforschung
Germany
Braunschweig
38124
Inhoffenstr. 7

EURAXESS offer ID: 652810

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