Novel mechanisms of hypoxic metabolic reprogramming in metastatic cancers

Competitive Ad Astra PhD Studentship:

Novel mechanisms of hypoxic metabolic reprogramming in metastatic cancers

A three-year funded PhD studentship opportunity is available in the laboratory of Dr. Luana Schito at the Conway Institute of Biomolecular and Biomedical Research and UCD School of Medicine, University College Dublin, Ireland. The Schito lab focuses on the discovery of novel mechanisms of metabolic reprogramming under low oxygen (hypoxia) in cancer cells engaging in metastatic dissemination, a key process responsible for oncologic mortality in the clinic.

The selected candidate will carry out experimental work by utilizing in vitro models of advanced metastatic cancers, under the supervision and direction of Dr. Luana Schito.

For this position:

1. Previous experience in cellular culture, aseptic technique and basic molecular biology techniques is an asset
2. Conscientiousness, adaptability and the ability to follow experimental directions and guidance are essential assets
3. A previous publication record is desirable, but not a mandatory requirement

The project offers an opportunity for acquiring advanced training in cutting-edge experimental approaches addressing the overall scientific objectives, whilst opening possibilities of engagement with a network of national and international collaborations, including leading experts in hypoxic signaling and cancer metabolism.

The Ad Astra PhD Studentship includes a stipend of €18,000 per annum and a research budget covering costs associated with the project (maximum of three years and renewable annually upon satisfactory progress and academic requirements). The selected candidate will be enrolled onto a structured PhD program at UCD, which includes some taught elements and transferrable skills training, thus providing an excellent foundation for a research career in academia or industry.

The position is open to both EU and non-EU candidates, including a full tuition-fee waiver.

For details see: https://www.ucd.ie/graduatestudies/researchprogrammes/structuredphd/

Applicant Requirements

Applicants must have reached a minimum of an upper second-class (2.1) degree or equivalent in a relevant honors Bachelors or Masters degree. Excellent written, oral communication skills and a high level of competence in the English language (proven by a recent, standardized English test; please see: http://www.ucd.ie/registry/admissions/elr.html) are essential.

Application Details

A complete application package, to be sent as a single .pdf document, should contain:

1. A cover letter addressing the specif motivations driving the applicant onto the project, detailing relevant previous experience.
2. A detailed CV including a list of publications (if applicable).
3. The names and contact details of at least two academic referees (please do not include letters of recommendation in the application package).

Application Deadline: 21-05-2021, 5:00 pm (GMT)

Interviews will be conducted through Zoom after the application deadline. Please note that only selected candidates will be contacted.

Application package can be submitted via email to:

Luana Schito, MSc, PhD at: luana.schito@ucd.ie