ORGANISATION/COMPANYUniversity of Mainz
RESEARCH FIELDBiological sciences › BiologyChemistry › Other
RESEARCHER PROFILERecognised Researcher (R2)
APPLICATION DEADLINE31/10/2021 14:00 - Europe/Athens
LOCATIONGermany › Mainz
TYPE OF CONTRACTTemporary
HOURS PER WEEK40
OFFER STARTING DATE01/02/2022
EU RESEARCH FRAMEWORK PROGRAMMEH2020 / ERC
Interactive DNA-Mechanosensing Materials to Instruct Cell Behavior
Key words: DNA hydrogels, cell culture, mechanobiology, signaling research
In the framework of an ERC Consolidator Grant, the Walther Lab at the University of Mainz is searching for an ambitious and highly skilled postdoctoral researcher in the area of artificial extracellular matrix materials to understand cell behavior in interaction with mechanosensing DNA hydrogel materials. The project is strongly interdisciplinary, and connects DNA nanotechnology and hydrogel materials with mechanobiology of mammalian cells. The main aim is to establish communication channels between synthetic DNA materials and cells using the exchange of mechanical and chemical information so that the material and the cells co-evolve in a fully interactive manner.
We provide you with an inspiring and collaborative team atmosphere in a multinational and multidisciplinary environment, and ample opportunities to develop towards an individual scientific profile. Cutting-edge analytical infrastructure and facilities are available due to generous support by the University of Mainz and the Gutenberg Research College. A brand-new DNA nanoscience lab and a brand-new cell lab with state-of-the-art infrastructure will accelerate discoveries and make your life as a researcher convenient.
Selected references on the topic:
- Merindol, R.; Delechiave, G.; Heinen, L.; Catalani, L. H.; Walther, A. “Modular Design of Programmable Mechanofluorescent DNA Hydrogels” Nature Commun. 10, 529 (2019).
- Creusen, G.; Schmidt, R. S.; Walther, A. One-Component DNA Mechanoprobes for Facile Mechanosensing in Photopolymerized Hydrogels and Elastomers ACS Macro Letters, 10, 671 (2021)
- Walther, A.; “From Responsive to Adaptive and Interactive Materials and Materials Systems: A Roadmap” Adv. Mater. 1905111 (2019) (Invited View Point).
- Ma, V.; Salaita K. “DNA Nanotechnology as an Emerging Tool to Study Mechanotransduction in Living Systems” Small, 1900961 (2019).
The Walther Lab on Active, Adaptive and Autonomous Bioinspired Materials Systems has pioneered complex soft matter systems in and out-of-equilibrium with a focus on bioinspired and life-inspired materials systems. More information on the group can be found here: www.walther-group.com
EXPECTED CANDIDATE PROFILE
As an ideal candidate you are creative, highly self-motivated, ambitious and communicative to excel in scientific challenges, and have a proven track record with innovative publications in cell culture, extracellular matrix materials, mechanobiology, and hydrogels. Previous research experience in DNA-based materials or molecular force-sensing is a plus.
The position is according to the German salary scale with full social benefits. It is available from end 2021/beginning 2022, and has a duration of 2 + 2 (extension possible) years. Bridge funding for an earlier start could be provided. Application Deadline is end of October 2021.
Please send your full application as a single PDF file containing
- letter of motivation including a summary of your past research experience, in particular a meaningful summary of your PhD and master thesis
- Detail in your letter why you believe you are the right person and what you expect from us and from your postdoctoral research stay
- curriculum vitae and list of publications
- Two contacts for reference letters
to firstname.lastname@example.org (Contact AW for more information)
Prof. Dr. Andreas Walther, University of Mainz, Germany
EURAXESS offer ID: 629331
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