Science 4 Refugees

Postdoc - regulation of the mitochondrial calcium uniporter complex (f/m/x)

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    Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt
    Medical sciences
    Recognised Researcher (R2)
    Established Researcher (R3)
    14/06/2021 23:59 - Europe/Brussels
    Germany › Neuherberg (bei München)
    To be defined


Area of research:

Scientific / postdoctoral posts

Starting date:

Fri, 26 Mar 2021

Contract time limit:

Mon, 14 Jun 2021

Job description:

Helmholtz Zentrum München is a research center with the mission to discover personalized medical solutions for the prevention and therapy of environmentally triggered diseases and promote a healthier society in a rapidly changing world.At our institute you will find a scientifically stimulating international environment. Together with renowned scientists and supported by an excellent infrastructure you will have the opportunity to make an important contribution for a healthier society. We are looking for a highly motivated postdoctoral fellow to join our international research team at the Institute for Diabetes and Obesity (IDO) of the newly established (HDC) in Munich. The Helmholtz Center Munich is a member of one of the leading research associations in Europe – the Helmholtz Association of German Research Centers. Our laboratory (Research Unit in Functional Genomics of Mitochondria, headed by Dr. Fabiana Perocchi) is interested in characterizing mitochondrial signal transduction cascades that occur in response to physiological and pathophysiological stimuli (e.g. exercise and diet). We develop experimental and computational strategies to predict, test, and reverse the effects of genetic and chemical perturbations on mitochondrial metabolism. To this goal, we combine genomics, proteomics, and metabolomics approaches with traditional genetic, biochemical, and physiological techniques applied to mouse models, human cell lines and patient samples. The aim of the postdoc research project is to characterize the role of newly identified calcium-regulated proteins in mitochondrial signaling and metabolism.Postdoc - regulation of the mitochondrial calcium uniporter complex (f/m/x) 100561 close to full time Neuherberg near Munich Postdocs Your responsibilities - Study of the regulation of the mitochondrial calcium uniporter complex- Define the role of new interactors on MCU and bioenergetics- Characterize the MCU complex stoichiometry in mouse tissues- Train PhD students in calcium imaging- Writing of manuscriptsYour qualifications- Strong experimental skills in calcium imaging (mandatory)- Strong experimental skills in live imaging and immunofluorescence (mandatory)- Strong experimental skills in generating genetically modified cell lines through viral vectors (lentivirus, retrovirus, adenovirus; CRISPR-Cas9)- Strong experimental skills in mouse phenotyping, animal handling, and surgical procedure (mandatory)What we offer you continuous education and training work-life balance flexible working hours & time off in lieu 30 days annual leave on-site health management service mobile work on-site nursery elder care company pension scheme discounted public transport ticket Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (TV EntgO Bund). The position is (initially) limited to 1, but under certain circumstances an extension can be arranged.To promote diversity, we welcome applications from talented people regardless of cultural background, nationality, ethnicity, gender and sexual identity, physical abilities, religion and age until . Qualified applicants with physical disabilities will be given preference.Interested? If you have further questions, simply contact Fabiana Perocchi, +49 89 3187-43056, who will be happy to be of assistance. Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Institute for Diabetes and Obesity Ingolstädter Landstraße 1 85764 Neuherberg near Munich Award for excellent gender equality policy for women and men. Helmholtz Zentrum München is particularly committed to promoting professional equality between women and men. It therefore aims to increase the proportion of the underrepresented sex in the respective field. The Helmholtz Zentrum München is part of the Helmholtz Association, Germany's largest scientific organization. Altogether 42.000 people currently work in its 19 scientific-technical and biological-medical research centers. The Association's annual budget amounts to around 5 billion Euros.

This research center is part of the Helmholtz Association of German Research Centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany's largest scientific organisation.

Work location(s)
1 position(s) available at
Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt
Neuherberg (bei München)

EURAXESS offer ID: 620828
Posting organisation offer ID: ae4fc13aaa7304f3902ba7b8a4f0e1d6bc892645


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