Job Information
- Organisation/Company
- Fundación Universidad Católica de Valencia San Vicente Martír
- Department
- Department of Physiology and Anatomy
- Research Field
- All
- Researcher Profile
- First Stage Researcher (R1)
- Country
- Spain
- Application Deadline
- Type of Contract
- Temporary
- Job Status
- Full-time
- Offer Starting Date
- Is the job funded through the EU Research Framework Programme?
- HE / MSCA
- Reference Number
- 1
- Marie Curie Grant Agreement Number
- 101073316
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
10 doctoral candidate (DC) positions are available in the framework of the Marie Skłodowska Curie - Doctoral Networks (MSCA-DN) project “Targeting RNA as an approach for treating retinal disease” (RETORNA).
RETORNA aims to treat retinal diseases (RD) by using RNA therapy. Among the research objectives, we will study different types of RNA that are expressed in retinal cells. By observing bioinformatic models, cell and tissue cultures, animal models, and human patients, we will be able to create RNA profiles for different RD. This screening will identify several targets that will be used as therapeutic approaches. Then, selected RNAs will be used to treat different RD, such as macular degeneration and retinitis pigmentosa.
The proposed doctoral network (DN) will provide an innovative, international, multi/interdisciplinary platform to train young scientists in the field of vision science. RETORNA proposes breakthrough research, distributed in 10 individual projects, performed by 10 Doctoral candidates (DCs) in the following countries: Spain, Netherlands, Turkey, Germany, Italy and Ireland.
The following 10 INDIVIDUAL PROJECTS are available:
DC1: Micro RNA expression, identification, and functional characterization under oxidative stress challenge in diabetic retinopathy
Host supervisor: Dr. Jorge Barcia González (Universidad Católica de Valencia, Spain)
DC2: Targeting of diabetic retinopathy by micro RNA in a human retinal organoid model
Host supervisor: Dr. Zohreh Hosseinzadeh (Leipzig University, Germany)
DC3: Expression of RNA based TrkB-aptamers for the treatment of age-related macular degeneration
Host supervisor: Dr. Sven Schnichels (Tübingen University, Germany)
DC4: Study of micro RNA expression profile in Central Areolar Choroidal Dystrophy. Translational study using a new CRISPR-generated animal model
Host supervisor: Dr. Nicolás Cuenca (Universidad de Alicante, Spain)
DC5: Designing of novel aptamer-based AT1R targeted therapeutics against retinal degeneration
Host supervisor: Dr. Serdar Durdagi (Bahcesehir University, Turkey)
DC6: Prevention of premature photoreceptor cell death in CRB1 retinitis pigmentosa models by RNA modulation
Host supervisor: Dr. Jan Wijnholds (Leiden University Medical Center, The Netherlands)
DC7: Examining Health Economic Impacts of RNA in treating retinal diseases
Host supervisor: Dr. Aileen Murphy (University of Cork, Ireland)
DC8: CRISPR therapy in a retinal hereditary dystrophy. Translational study using an animal model and retinal organotypic cultures
Host supervisor: Dr. Natalia Martínez-Gil (Universidad de Alicante, Spain)
DC9: Evaluation by RNA-seq-based approaches of the global role of microRNAs and of other noncoding RNAs in the human and mouse retina in both physiological and pathological conditions
Host supervisor: Dr. Sandro Banfi (Telethon Institute of Genetics and Medicine, Naples, Italy)
DC10: Retinal miRNAs as molecular targets for the treatment of retinitis pigmentosa
Host supervisor: Dr. Javier Sancho-Pelluz (Universidad Católica de Valencia, Spain)
Requirements
- Research Field
- All
- Education Level
- Master Degree or equivalent
Candidates reseachers must:
- have MSc level training in life sciences (Biology, Medicine, Pharmacy, Biotech - DC 1,2,3,4,6,8,9,10), Technology (Bioengineering) (DC5), Health Economics (DC7) or any other field that matches the particular project for which they apply
- possess scientific skills for the project that they apply for and research experience (read the Specific Requirements for each project)
- possess a good working level of English: candidates must demonstrate during the interview a good ability to understand and express themselves in both written and spoken English, sufficiently high to fully benefit from the experience (read the Specific Requirements for each project)
- be highly motivated
- be creative and possess a high level of independency
Specific Requirements listed below based on each project:
DC1:
- Master degree or equivalent in the fields related to the project
- Basic biology lab tecniques, scientific background
- Desirable technical competences: experience in handling lab animals, cells cultures
- Good English level - no certification required
DC2:
- Master degree in Biology or relevant fields related to the project
- Desirable technical competences: cell culture, regular molecular biology methods, preferable having experience of electrophysiology
- Good English level - no certification required
DC3:
- Master degree in the field of Biological Sciences or Biochemistry, Neuroscience, Nanoscience or similar related to the project
Technical competences: cell culture, molecular biology are needed. Experience in cloning techniques and knowledge of DNA chemistry are desired.
- Good English level - no certification required
DC4:
- Master degree in the field of Biomedicine, Health Sciences, Neurosciences or similar related to the project
- Good English level - no certification required
DC5:
- Master degree with thesis
- GRE result of at least 151 in the quantitative score type or GMAT result of at least 465 in total
- Python knowledge
- English Proficiency Result Certificate (YDS:65, TOEFL:79, YÖKDIL:65) is required.(For English Language Education Program; YDS: 80, YÖKDIL: 80, TOEFL: 96)
DC6:
Msc in Life Sciences is required (from a highly qualified University and approved by LUMC Graduate School).
Technical competences: laboratory research training (at least 6 to 9 months) during Msc, with a written Msc Thesis.
Good English level - no certification required
DC7:
- Candidate must have obtained a standard of at least Second Class Honours, Grade I, in an approved primary degree, or other such other evidence under the University's policy for Recognition of Prior Learning for Admission to Research Degrees.
- Desirable technical competences: experience in conducting systematic literature reviews, experience in conducting economic evaluations
- All postgraduate applicants whose first language is not English must provide evidence of English language proficiency.
- For further information and eligibility please see:https://www.ucc.ie/en/study/comparison/english/postgraduate/
DC8:
- Master degree in the field of Biomedicine, Health Sciences, Neurosciences or similar related to the project
- Good English level - no certification required
DC9:
- Master degree or equivalent in the fields related to the project
- Desirable technical competences: OMICS, animal models, molecular biology
- Good English level - no certification required
DC10:
- Master degree or equivalent in the fields related to the project
- Basic biology lab tecniques, scientific background
- Desirable technical competences: experience in handling lab animals, cells cultures
- Good English level - no certification required
- Languages
- ENGLISH
- Level
- Good
- Research Field
- Medical sciences » MedicineBiological sciences » Biological engineeringTechnology » BiotechnologyEconomics » Health economicsNeurosciences
Additional Information
RETORNA fellows will be employed according to the rules for Doctoral Candidates in MSCA DNs and the general regulations of each hosting institution.
The monthly financial package will include the following gross researcher allowances:
1) Living allowance of € 3,400.00 (country correction coefficient applies)
2) Mobility allowance of € 600.00
3) Family allowance of € 660.00 if applicable.
The final net monthly amount depends on the country destination and the family situation.
The guaranteed PhD funding is for 36 months starting from autumn 2023.
Other benefits:
All 10 doctorates will benefit from a large variety of activities foreseen for them. DCs at RETORNA will be provided with a unique multi-disciplinary and multi-sectoral training. First and foremost, DCs will be trained as scientists, each of them in their host institution, at their research secondments, and through local and network wide events. Next, thanks to the partnership between academic and non-academic entities, DCs will receive multi-sectoral inputs from both worlds. This will happen via lectures and workshops in our varied training program.
- candidates can be of any nationality
- must comply with the following mobility rule: researchers are required to undertake trans-national mobility (i.e., move from one country to another) and participate in all the activities foreseen by the project when taking up the appointment (trainings, summer courses, annual meetings, lectures, participation in conferences, public activities).
- possess a Master degree or an equivalent that allows the access to the doctoral program in the University they would like to candidate for (read the requirements for each University)
- be, at the date of recruitment, a doctoral candidate (i.e. not already in possession of a doctoral degree). Researchers who have successfully defended their doctoral thesis but who have not yet formally been awarded the doctoral degree will not be considered eligible.
- not have resided or carried out their main activity (work, studies, etc.) in the country of the recruiting beneficiary for more than 12 months in the 3 years immediately before the recruitment date. Short stays, such as holidays, are not taken into account.
The RETORNA selection procedure is open, transparent, merit-based and in line with the Code of Conduct for the Recruitment of Researchers and the European Charter for Researchers.
The criteria for recruitment of DCs will respect the principles of non-discrimination contained in The Charter of Fundamental Rights of the European Union.
It is the policy of the RETORNA project to promote and give equal opportunities regardless of gender and stimulate gender balance.
Documents required
Interested candidates should submit thefollowing documents via email to andreea.craciun@ucv.es for one (1) to maximum three (3) projects, indicating in the e-mail also the order of projects preference:
- a detailed CV, including – if applicable – relevant publications
- a motivation letter, indicating why you wish to conduct this research project
- two (2) letters of reference
- transcripts of bachelor and master degrees
- English certificate (mandatory if requested in the project applying for)
We encourage candidates to send any other certificates, representative publications, academic references or links demostrating the experience and interest in the project.
All documents must be named as "type of document_NameSurname" (i.e. Motivation letter_Andreea Craciun")
Selection process
The selection process will foreseen the following steps:
1. Eligibility: the RETORNA recruitment committee will check that each application is complete and that applicants fulfil the eligibility criteria described in the previous section.
2. Evaluation: each eligible application will be assessed independently by the principal investigators of our network, according to the project interests indicated by the candidate. The principal investigators will select up to four candidates per position for the following steps:
a. Online interviews: online interviews will be scheduled, in person interview will be organized where possible. Short-listed candidates will be invited for an online interview with the supervisor responsible for the research project of interest. At least one member of the recruitment committee will attend the online interviews.
b. Selection results: our recruitment committee will notify short-listed candidates of the results.
c. Hiring process and enrollment: the selected candidates will be put in touch with the corresponding principal investigator and the HR Department of the hosting institution to initiate the hiring procedure.
Applicants who have not been successful but who have received a positive evaluation will be put on a waiting list to cover possible withdrawals and future positions.
Project official description: https://cordis.europa.eu/project/id/101073316
Recruitment calendar:
- Call opening: 31st of January 2023
- Deadline for applications: 19th of March 2023
- Eligibility and Evaluation: 20th of March - 31st of March 2023
- Online Interviews: April 2023
- Notification to candidates: first week of May 2023
- Hiring process: May - July 2023
- Start date of the fellowship: September 2023
Work Location(s)
- Number of offers available
- 2
- Company/Institute
- Fundación Universidad Católica de Valencia San Vicente Martír
- Country
- Spain
- State/Province
- Spain
- City
- Valencia
- Number of offers available
- 1
- Company/Institute
- UNIVERSITAET LEIPZIG (ULEI)
- Country
- Germany
- City
- Leipzig
- Number of offers available
- 1
- Company/Institute
- EBERHARD KARLS UNIVERSITAET TUEBINGEN (EKUT)
- Country
- Germany
- City
- Tuebingen
- Number of offers available
- 2
- Company/Institute
- UNIVERSIDAD DE ALICANTE (UA)
- Country
- Spain
- City
- Alicante
- Number of offers available
- 1
- Company/Institute
- BAHCESEHIR UNIVERSITESI (BAU)
- Country
- Turkey
- City
- Istanbul
- Number of offers available
- 1
- Company/Institute
- ACADEMISCH ZIEKENHUIS LEIDEN (LUMC)
- Country
- Netherlands
- City
- Leiden
- Number of offers available
- 1
- Company/Institute
- UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (UCC)
- Country
- Ireland
- City
- Cork
- Number of offers available
- 1
- Company/Institute
- FONDAZIONE TELETHON ETS (FTELE.IGM)
- Country
- Italy
- City
- Pozzuoli
Where to apply
- andreea.craciun@ucv.es
Contact
- State/Province
- Spain
- City
- Valencia
- Street
- Calle Quevedo 2
- Postal Code
- 46001
- andreea.craciun@ucv.esfj.sancho@ucv.es