Postdoctoral position in bioinformatics

The Computational Biology and Bioinformatics group of the Brussels University (ULB) is seeking candidates for a postdoctoral position.

Research context:

The understanding of the biophysical mechanisms that drive single nucleobase substitutions in different regions of the human genome is one of the key questions of the post-genomic era. These mutations, whether inherited or somatic, are potentially responsible for a huge range of rare and complex diseases. The rationalization of these mechanisms is highly intricate, since base substitutions depend on the nucleotide sequence context and can be triggered by a wide range of physical, chemical or biological factors.

Objective:

In the AtOme project, we will bridge the gap between the atomic-level characterization of mutagenesis processes and the resulting phenotypic traits. More specifically, we will investigate the role of DNA charge transport in mutational and pathogenic processes using a multiscale computational approach combining quantum chemistry, machine learning and genomics.

Contact: Please submit: (1) a cover letter detailing your background and interest in the position, (2) a full CV and (3) two references (with name, email, address, phone number), to M. Rooman (mrooman@ulb.ac.be).