ORGANISATION/COMPANYInternational Giessen Graduate Centre for the Life Sciences
RESEARCH FIELDMedical sciences › Medicine
RESEARCHER PROFILEFirst Stage Researcher (R1)
APPLICATION DEADLINE11/04/2021 23:00 - Europe/Athens
LOCATIONGermany › Giessen
TYPE OF CONTRACTTemporary
HOURS PER WEEK20
The longstanding interest of orthodontic laboratory uses molecular, cellular, genetic and genomic approaches to investigate cell signaling during orthodontic tooth movement. We mainly focus on the interaction among osteoblasts, osteoclasts, periodontal ligament fibroblasts and cementoblasts, and we are exploiting these microenvironments to mimic orthodontic tooth movement. With these systems we are able to explore cell/rat/human biology and the regulation of alveolar bone homeostasis to address the underlying mechanisms during remodeling.
The Mechanobiology & Signaling Transduction Laboratory is headed by Prof. Dr. Sabine Ruf and Dr. Sabine Groeger. Main research topics are force-cell transduction in orthodontic tooth movement, proteomics and genetics of cementum remodeling, and rat experiments. Our laboratory aims for excellence in research and makes all efforts to publish its work in top scientific and medical journals. Training of young scientists is also a key aspect of our laboratory, with a very successful history.
The applicants must have a master degree and a proof of a proficiency in English (B2 or equivalent) which are pre-requisites for a successful admission to the GGL (Giessen Graduate Centre for the Life Sciences) and the PhD program of the Faculty of Medicine (3 years). We seek highly motivated young applicants who can work cooperatively. Your previous research topic could be medicine, chemistry, veterinary medicine, biology and dentistry. These projects involve the use of genetically engineered rats, cell and molecular biology as well as culture of primary cells and cell lines. Commensurate with experience, first author publication(s) in top-tier bone and/or cell and molecular biology journals, expertise in signal transduction analysis will be considered beneficial but not a requirement. Western blot analysis and PCR data analysis, specifically bulk and single cell RNA-seq, will be considered beneficial but not a requirement.
PhD program is tuition-free, the applicant must have a scholarship to cover the personal living expenses.
EURAXESS offer ID: 609768
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