04/02/2021
The Human Resources Strategy for Researchers

Biofilms - From Structure-Function Studies to Antimicrobial Discovery (HEMMINGSA_U21SF)

This job offer has expired


  • ORGANISATION/COMPANY
    University of East Anglia
  • RESEARCH FIELD
    Biological sciencesOther
    ChemistryBiochemistry
    PhysicsBiophysics
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    31/05/2021 23:00 - Europe/London
  • LOCATION
    United Kingdom › Norwich
  • TYPE OF CONTRACT
    Other
  • JOB STATUS
    Other
  • OFFER STARTING DATE
    01/10/2021

OFFER DESCRIPTION

Treatment of bacterial infections is often made more difficult by their capacity to resist antibiotics and this resistance is widely recognized as a major threat to public health. In many cases the most persistent and dangerous infections are associated with the capacity of the infecting bacteria to form a complex 3D colony known as a biofilm.  

An exciting PhD research studentship is available in the groups of Professors Andrew Hemmings and Changjiang Dong (Structural and Molecular Biology) and Dr. Gary Rowley (Microbiology) to study the structure-function relationships of protein complexes involved in synthesis, editing and translocation of biofilm exopolysaccharide in pathogenic bacteria. This information will provide a foundation for the discovery of inhibitory compounds with potential for development as antimicrobials. To achieve this the successful candidate will receive training in modern methods of molecular and structural biology, including X-ray crystallography and cryoelectron microscopy, and molecular microbiology. The research will make extensive use of our excellent local facilities including the UEA Centre for Structural and Molecular Biochemistry and external facilities such as the synchrotron at the Diamond Light Source. 

Suitably qualified individuals will have a strong interest in antimicrobial resistance and will hold, or expect to hold, a first class honours undergraduate or good Masters degree (or equivalent) from any of a range of disciplines including, but not restricted to chemistry, biochemistry, biological chemistry or microbiology. 

For more information on the supervisor for this project, please go here https://people.uea.ac.uk/a_hemmings

The studentship length is 3 years. 

Applications are processed as soon as they are received and the project may be filled before the closing date, so early application is encouraged.

Funding Notes: 

This PhD project is offered on a self-funding basis.  It is open to applicants with funding or those applying to funding sources.  Details of tuition fees can be found at https://www.uea.ac.uk/about/university-information/finance-and-procurement/finance-information-for-students/tuition-fees 

A bench fee is also payable on top of the tuition fee to cover specialist equipment or laboratory costs required for the research.  Applicants should contact the primary supervisor for further information about the fee associated with the project. 

More Information

Offer Requirements

Specific Requirements

Acceptable first degree including (but not restricted to) chemistry, biochemistry, biological chemistry or microbiology. Suitably qualified individuals will have a strong interest in antimicrobial resistance will hold, or expect to hold, a first class honours undergraduate or good Masters degree (or equivalent).

Work location(s)
1 position(s) available at
University of East Anglia
United Kingdom
Norwich
NR4 7TJ
University of East Anglia, Norwich Research Park, Norwich

EURAXESS offer ID: 601689

Disclaimer:

The responsibility for the jobs published on this website, including the job description, lies entirely with the publishing institutions. The application is handled uniquely by the employer, who is also fully responsible for the recruitment and selection processes.

 

Please contact support@euraxess.org if you wish to download all jobs in XML.