03/02/2021
European Research Council

Post-doc Researcher in Computational Glycobiology

This job offer has expired


  • ORGANISATION/COMPANY
    Universitat de Barcelona
  • RESEARCH FIELD
    Chemistry
  • RESEARCHER PROFILE
    Recognised Researcher (R2)
  • APPLICATION DEADLINE
    28/02/2021 00:00 - Europe/Athens
  • LOCATION
    Spain › Barcelona
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    37,5
  • OFFER STARTING DATE
    01/07/2021
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / ERC

OFFER DESCRIPTION

Professor Carme Rovira is looking for two post-docs to work in computational glycobiology. They will be applying state-of-art computational methods to model enzymatic reactions and glycan-protein interactions, developing new algorithms and applying them to the analysis of simulation data to aid drug discovery. The successful candidates will work on the prestigious ERC Synergy grant of Prof. Rovira, together with Prof. Gideon J. Davies (University of York) and Prof. Herman S. Overkleeft (University of Leiden). The perspective researcher will have the opportunity to work on a very exciting project CARBOCENTRE, which aims at developing novel activity-based probes and competitive inhibitors for carbohydrate-active enzymes of interest in biomedicine and biotechnology. She/he will address complex enzyme reaction mechanisms and apply sophisticated computational methods and algorithms (ab initio molecular dynamics, quantum mechanics/molecular mechanics methodologies and enhanced sampling techniques). The aim is to utilize computational data to understand catalysis in carbohydrate-active enzymes (CAZymes) and contribute to the design of activitybased probes for disease-relevant CAZymes, diagnosis markers and selective drugs. The successful candidates will join the dynamic research group of Prof. Rovira within the Institute of Theoretical and Computational Chemistry and the Department of Chemistry. They will work in a sophisticated HPC environment, will have access to systems and computational infrastructures, and will be involved in collaborations with experts in different areas. The project is a collaboration of the Department of Chemistry of the University of Barcelona (Spain), the York Structural Biology Laboratory of the University of York (UK) and the Leiden Institute of Chemistry of the University of Leiden (the Netherlands). The position is available from July 1st, 2021 for a duration of two years (one year, renewable to a second one). There is also the possibility of renewal to a third year upon funding. The position will be based at the Chemistry Department of the UB in Barcelona, Spain. Key Duties  Conduct high-quality research  Publish in high impact journals  Present research at national and international conferences and meetings 2  Collaborate with various research groups across Europe and elsewhere  Help supervise PhD and MSc students  Participate in grant writing and organizational activities  Participate in educational and outreach activities

 

 Acronym CARBOCENTRE

Project title Activity-Based Profiling of Glycoprocessing Enzymes for Human Health and a Sustainable Society

IP Carme Rovira

Department Department of Chemistry

 Gross salary per year: We offer a competitive salary in line with the most prestigious government fellowships and according to the cost of living in Barcelona.

 Required documents

1) Application letter including a summary of previous research.

2) Full Curriculum Vitae including contact details and publication list.

3) Academic transcripts from all Undergraduate, MSc and PhD degrees.

4) Two letters of recommendation (minimum) from scholars that have/had professional relation with the applicant, including the PhD supervisor. The referees (not the applicant) should email their letters directly to recruitment.roviralab@gmail.com  before the deadline. Please include the name of the applicant in the subject of the e-mail (e.g. Reference letter for postdoc applicant Sarah Smith). 3 Send your application to: email recruitment.roviralab@gmail.com   Name Carme Rovira email subject ERC postdoc application

More Information

Eligibility criteria

Adequacy of the candidate to the position being advertised  CV and skills/qualifications of the candidate

Selection process

A committee formed by three scientists of the CARBOCENTER team, including the Barcelona PI will make a shortlist. Prospective candidates are expected to be contacted for interview before 31/03/2021.

Additional comments

The start of postdoc project is envisaged for July 2021, but it will be possible to start later, between July 2021 and December 2021. Diversity and Equal Opportunity Employment UB is an equal opportunity employer committed to diversity and inclusion. We are pleased to consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or any other basis protected by applicable state or local law.

Web site for additional job details

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Chemistry: PhD or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Excellent

Skills/Qualifications

We are looking for a highly motivated scientist who has research background and expertise in Computational Chemistry. A biology background, a sound understanding of carbohydrate chemistry and organic chemistry reactions, experience in protein modelling, molecular dynamics simulations, glycochemistry and glycobiology would be a plus. Additional skills:  Experience in computational chemistry and enzyme-catalyzed reactions  Good publication record for the career stage  Fluency in spoken and written English  Good technical skills including at least two of the following: quantum 4 chemistry methods, molecular dynamics, statistics, scripting and programming.

Specific Requirements

At the time of recruitment by the host organisation, the candidates should have a PhD degree in Chemistry, Physics, Computational biology, Structural biology, Biochemistry or a related discipline. The date of the degree should be earlier than May 1 st , 2021.

 "All required documents should be sent to recruitment.roviralab@gmail.com

with the subject "ERC postdoc application".

Work location(s)
1 position(s) available at
Universitat de Barcelona
Spain
Barcelona
Barcelona
08028
Martí i Franquès 1

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EURAXESS offer ID: 601041

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